CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 25 atoms

11 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
11
With full pages
2
Scaffold SMILES

O=C(NCCc1cscn1)OCC1c2ccccc2-c2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCCc1cscn1)OCC1c2ccccc2-c2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

Fmoc-D-4-Thiazolylalanine chemical structure, C21H18N2O4S, CAS 205528-33-2
Fmoc-D-4-Thiazolylalanine
CAS 205528-33-2C21H18N2O4S
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(thiazol-4-yl)propanoic acid chemical structure, C21H18N2O4S, CAS 205528-32-1
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(thiazol-4-yl)propanoic acid
CAS 205528-32-1C21H18N2O4S
2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(1,3-thiazol-4-yl)propanoic acid chemical structure, C21H18N2O4S, CAS 1696377-69-1
2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(1,3-thiazol-4-yl)propanoic acid
CAS 1696377-69-1C21H18N2O4S
Methyl (2R)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-3-(1,3-thiazol-4-yl)propanoate chemical structure, C22H20N2O4S, CAS 1820574-14-8
Methyl (2R)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-3-(1,3-thiazol-4-yl)propanoate
CAS 1820574-14-8C22H20N2O4S
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-3-(thiazol-4-yl)propanoic acid chemical structure, C22H20N2O4S, CAS 1446478-22-3
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-3-(thiazol-4-yl)propanoic acid
CAS 1446478-22-3C22H20N2O4S
2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(2-methyl-1,3-thiazol-4-yl)propanoic acid chemical structure, C22H20N2O4S, CAS 1379830-81-5
2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(2-methyl-1,3-thiazol-4-yl)propanoic acid
CAS 1379830-81-5C22H20N2O4S
3-(2,5-Dimethyl-1,3-thiazol-4-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid chemical structure, C23H22N2O4S, CAS 2145423-71-6
3-(2,5-Dimethyl-1,3-thiazol-4-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
CAS 2145423-71-6C23H22N2O4S
3-(2-Chloro-1,3-thiazol-4-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid chemical structure, C21H17ClN2O4S, CAS 2171600-56-7
3-(2-Chloro-1,3-thiazol-4-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
CAS 2171600-56-7C21H17ClN2O4S
3-(5-Chloro-1,3-thiazol-4-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid chemical structure, C21H17ClN2O4S, CAS 2156647-80-0
3-(5-Chloro-1,3-thiazol-4-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
CAS 2156647-80-0C21H17ClN2O4S
(2S)-3-(2-Chloro-1,3-thiazol-4-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid chemical structure, C21H17ClN2O4S, CAS 2770452-85-0
(2S)-3-(2-Chloro-1,3-thiazol-4-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
CAS 2770452-85-0C21H17ClN2O4S
Fmoc-3-(2-methylthiazol-4-yl)-L-alanine chemical structure, C22H20N2O4S, CAS 1185853-99-9
Fmoc-3-(2-methylthiazol-4-yl)-L-alanine
CAS 1185853-99-9C22H20N2O4S