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Murcko scaffold

2-Phenoxy-N-(4-pyridin-4-yl-thiazol-2-yl)-acetamide scaffold

18 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 22
Chemicals: 18
With full pages: 8

Scaffold SMILES

O=C(COc1ccccc1)Nc1nc(-c2ccncc2)cs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 2-Phenoxy-N-(4-pyridin-4-yl-thiazol-2-yl)-acetamide page

Murcko scaffold O=C(COc1ccccc1)Nc1nc(-c2ccncc2)cs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 18 of 18 chemicals

2-(2,4-Dichlorophenoxy)-N-(4-(pyridin-4-yl)thiazol-2-yl)acetamide chemical structure, C16H11Cl2N3O2S, CAS 476631-63-7

2-(2,4-Dichlorophenoxy)-N-(4-(pyridin-4-yl)thiazol-2-yl)acetamide

CAS 476631-63-7C₁₆H₁₁Cl₂N₃O₂S

2-(4-Chlorophenoxy)-N-(4-(pyridin-4-yl)thiazol-2-yl)acetamide chemical structure, C16H12ClN3O2S, CAS 476631-60-4

2-(4-Chlorophenoxy)-N-(4-(pyridin-4-yl)thiazol-2-yl)acetamide

CAS 476631-60-4C₁₆H₁₂ClN₃O₂S

2-Phenoxy-N-(4-pyridin-4-yl-thiazol-2-yl)-acetamide chemical structure, C16H13N3O2S, CAS 476631-61-5

2-Phenoxy-N-(4-pyridin-4-yl-thiazol-2-yl)-acetamide

CAS 476631-61-5C₁₆H₁₃N₃O₂S

2-(4-Chloro-2-methylphenoxy)-N-(4-(pyridin-4-yl)thiazol-2-yl)acetamide chemical structure, C17H14ClN3O2S, CAS 946361-30-4

2-(4-Chloro-2-methylphenoxy)-N-(4-(pyridin-4-yl)thiazol-2-yl)acetamide

CAS 946361-30-4C₁₇H₁₄ClN₃O₂S

2-(2-Methylphenoxy)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide chemical structure, C17H15N3O2S, CAS 879160-89-1

2-(2-Methylphenoxy)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide

CAS 879160-89-1C₁₇H₁₅N₃O₂S

2-(3,4-Dimethylphenoxy)-N-(4-(pyridin-4-yl)thiazol-2-yl)acetamide chemical structure, C18H17N3O2S, CAS 946361-26-8

2-(3,4-Dimethylphenoxy)-N-(4-(pyridin-4-yl)thiazol-2-yl)acetamide

CAS 946361-26-8C₁₈H₁₇N₃O₂S

2-(2-Chlorophenoxy)-N-(4-(pyridin-4-yl)thiazol-2-yl)acetamide chemical structure, C16H12ClN3O2S, CAS 878923-25-2

2-(2-Chlorophenoxy)-N-(4-(pyridin-4-yl)thiazol-2-yl)acetamide

CAS 878923-25-2C₁₆H₁₂ClN₃O₂S

2-(3-Fluorophenoxy)-N-(4-(pyridin-4-yl)thiazol-2-yl)acetamide chemical structure, C16H12FN3O2S, CAS 692878-18-5

2-(3-Fluorophenoxy)-N-(4-(pyridin-4-yl)thiazol-2-yl)acetamide

CAS 692878-18-5C₁₆H₁₂FN₃O₂S

2-(2,5-Dimethylphenoxy)-N-(4-(pyridin-4-yl)thiazol-2-yl)acetamide chemical structure, C18H17N3O2S, CAS 946261-23-0

2-(2,5-Dimethylphenoxy)-N-(4-(pyridin-4-yl)thiazol-2-yl)acetamide

CAS 946261-23-0C₁₈H₁₇N₃O₂S

2-(4-Bromophenoxy)-N-(4-(pyridin-4-yl)thiazol-2-yl)acetamide chemical structure, C16H12BrN3O2S, CAS 946341-18-0

2-(4-Bromophenoxy)-N-(4-(pyridin-4-yl)thiazol-2-yl)acetamide

CAS 946341-18-0C₁₆H₁₂BrN₃O₂S

2-(4-tert-Butylphenoxy)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide chemical structure, C20H21N3O2S, CAS 946341-15-7

2-(4-tert-Butylphenoxy)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide

CAS 946341-15-7C₂₀H₂₁N₃O₂S

2-Phenoxy-N-(4-(pyridin-4-yl)thiazol-2-yl)propanamide chemical structure, C17H15N3O2S, CAS 878923-20-7

2-Phenoxy-N-(4-(pyridin-4-yl)thiazol-2-yl)propanamide

CAS 878923-20-7C₁₇H₁₅N₃O₂S

N-(4-(Pyridin-4-yl)thiazol-2-yl)-2-(m-tolyloxy)acetamide chemical structure, C17H15N3O2S, CAS 692875-60-8

N-(4-(Pyridin-4-yl)thiazol-2-yl)-2-(m-tolyloxy)acetamide

CAS 692875-60-8C₁₇H₁₅N₃O₂S

2-(3-Methylphenoxy)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide chemical structure, C18H17N3O2S, CAS 879162-58-0

2-(3-Methylphenoxy)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide

CAS 879162-58-0C₁₈H₁₇N₃O₂S

2-(3-Methoxyphenoxy)-N-(4-(pyridin-4-yl)thiazol-2-yl)acetamide chemical structure, C17H15N3O3S, CAS 946341-12-4

2-(3-Methoxyphenoxy)-N-(4-(pyridin-4-yl)thiazol-2-yl)acetamide

CAS 946341-12-4C₁₇H₁₅N₃O₃S

2-(4-Fluorophenoxy)-N-(4-(pyridin-4-yl)thiazol-2-yl)acetamide chemical structure, C16H12FN3O2S, CAS 692875-37-9

2-(4-Fluorophenoxy)-N-(4-(pyridin-4-yl)thiazol-2-yl)acetamide

CAS 692875-37-9C₁₆H₁₂FN₃O₂S

2-(4-Ethylphenoxy)-N-(4-(pyridin-4-yl)thiazol-2-yl)acetamide chemical structure, C18H17N3O2S, CAS 946226-10-4

2-(4-Ethylphenoxy)-N-(4-(pyridin-4-yl)thiazol-2-yl)acetamide

CAS 946226-10-4C₁₈H₁₇N₃O₂S

N-[4-(Pyridin-4-yl)-1,3-thiazol-2-yl]-2-(2,4,5-trichlorophenoxy)acetamide chemical structure, C16H10Cl3N3O2S, CAS 946226-14-8

N-[4-(Pyridin-4-yl)-1,3-thiazol-2-yl]-2-(2,4,5-trichlorophenoxy)acetamide

CAS 946226-14-8C₁₆H₁₀Cl₃N₃O₂S