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Murcko scaffold

N-Phenyl-2-[(5-pyridin-4-yl-1H-1,2,4-triazol-3-yl)sulfanyl]acetamide scaffold

286 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
286
With full pages
78
Scaffold SMILES

O=C(CSc1nnc(-c2ccncc2)[nH]1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-Phenyl-2-[(5-pyridin-4-yl-1H-1,2,4-triazol-3-yl)sulfanyl]acetamide page
Murcko scaffold O=C(CSc1nnc(-c2ccncc2)[nH]1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 286 chemicals

N-(3,4-Dimethyl-phenyl)-2-(4-methyl-5-pyridin-4-yl-4H-[1,2,4]triazol-3-ylsulfanyl)-acetamide chemical structure, C18H19N5OS, CAS 338425-34-6
N-(3,4-Dimethyl-phenyl)-2-(4-methyl-5-pyridin-4-yl-4H-[1,2,4]triazol-3-ylsulfanyl)-acetamide
CAS 338425-34-6C18H19N5OS
4-[2-(4-Methyl-5-pyridin-4-yl-4H-[1,2,4]triazol-3-ylsulfanyl)-acetylamino]-benzoic acid methyl ester chemical structure, C18H17N5O3S, CAS 338425-42-6
4-[2-(4-Methyl-5-pyridin-4-yl-4H-[1,2,4]triazol-3-ylsulfanyl)-acetylamino]-benzoic acid methyl ester
CAS 338425-42-6C18H17N5O3S
2-(4-Methyl-5-pyridin-4-yl-4H-[1,2,4]triazol-3-ylsulfanyl)-N-m-tolyl-acetamide chemical structure, C17H17N5OS, CAS 338425-37-9
2-(4-Methyl-5-pyridin-4-yl-4H-[1,2,4]triazol-3-ylsulfanyl)-N-m-tolyl-acetamide
CAS 338425-37-9C17H17N5OS
2-(4-Allyl-5-pyridin-4-yl-4H-[1,2,4]triazol-3-ylsulfanyl)-N-(2,6-dimethyl-phenyl)-acetamide chemical structure, C20H21N5OS, CAS 562848-99-1
2-(4-Allyl-5-pyridin-4-yl-4H-[1,2,4]triazol-3-ylsulfanyl)-N-(2,6-dimethyl-phenyl)-acetamide
CAS 562848-99-1C20H21N5OS
2-[(4-Amino-5-pyridin-4-yl-1,2,4-triazol-3-yl)sulfanyl]-N-(2,5-dimethylphenyl)acetamide chemical structure, C17H18N6OS, CAS 840515-89-1
2-[(4-Amino-5-pyridin-4-yl-1,2,4-triazol-3-yl)sulfanyl]-N-(2,5-dimethylphenyl)acetamide
CAS 840515-89-1C17H18N6OS
2-((4-Amino-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(3,4-dimethylphenyl)acetamide chemical structure, C17H18N6OS, CAS 760193-87-1
2-((4-Amino-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(3,4-dimethylphenyl)acetamide
CAS 760193-87-1C17H18N6OS
N-[5-(Acetylamino)-2-methoxyphenyl]-2-(4-methyl-5-(4-pyridyl)(1,2,4-triazol-3-ylthio))acetamide chemical structure, C19H20N6O3S, CAS 575467-29-7
N-[5-(Acetylamino)-2-methoxyphenyl]-2-(4-methyl-5-(4-pyridyl)(1,2,4-triazol-3-ylthio))acetamide
CAS 575467-29-7C19H20N6O3S
Methyl 4-[2-(4-amino-5-(4-pyridyl)-1,2,4-triazol-3-ylthio)acetylamino]benzoate chemical structure, C17H16N6O3S, CAS 575461-98-2
Methyl 4-[2-(4-amino-5-(4-pyridyl)-1,2,4-triazol-3-ylthio)acetylamino]benzoate
CAS 575461-98-2C17H16N6O3S
N-(2-Ethylphenyl)-2-{[4-(prop-2-en-1-yl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C20H21N5OS, CAS 578736-53-5
N-(2-Ethylphenyl)-2-{[4-(prop-2-en-1-yl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide
CAS 578736-53-5C20H21N5OS
2-{[4-Ethyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-phenylacetamide chemical structure, C17H17N5OS, CAS 332883-45-1
2-{[4-Ethyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-phenylacetamide
CAS 332883-45-1C17H17N5OS
N-Phenyl-2-[(5-pyridin-4-yl-1H-1,2,4-triazol-3-yl)sulfanyl]acetamide chemical structure, C15H13N5OS, CAS 335218-59-2
N-Phenyl-2-[(5-pyridin-4-yl-1H-1,2,4-triazol-3-yl)sulfanyl]acetamide
CAS 335218-59-2C15H13N5OS
2-(4-Methyl-5-(4-pyridyl)(1,2,4-triazol-3-ylthio))-N-(4-methylphenyl)acetamide chemical structure, C17H17N5OS, CAS 482636-79-3
2-(4-Methyl-5-(4-pyridyl)(1,2,4-triazol-3-ylthio))-N-(4-methylphenyl)acetamide
CAS 482636-79-3C17H17N5OS
N-(4-Fluorophenyl)-2-{[4-methyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C16H14FN5OS, CAS 338425-59-5
N-(4-Fluorophenyl)-2-{[4-methyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide
CAS 338425-59-5C16H14FN5OS
2-((4-Amino-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(3-fluorophenyl)acetamide chemical structure, C15H13FN6OS, CAS 680599-26-2
2-((4-Amino-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(3-fluorophenyl)acetamide
CAS 680599-26-2C15H13FN6OS
N-(3-Fluorophenyl)-2-{[4-methyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C16H14FN5OS, CAS 557063-75-9
N-(3-Fluorophenyl)-2-{[4-methyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide
CAS 557063-75-9C16H14FN5OS
N-(4-Chlorophenyl)-2-[(5-pyridin-4-yl-1H-1,2,4-triazol-3-yl)sulfanyl]acetamide chemical structure, C15H12ClN5OS, CAS 578758-07-3
N-(4-Chlorophenyl)-2-[(5-pyridin-4-yl-1H-1,2,4-triazol-3-yl)sulfanyl]acetamide
CAS 578758-07-3C15H12ClN5OS
2-{[4-Amino-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(2-fluorophenyl)acetamide chemical structure, C15H13FN6OS, CAS 577698-81-8
2-{[4-Amino-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(2-fluorophenyl)acetamide
CAS 577698-81-8C15H13FN6OS
2-((4-Amino-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(4-fluorophenyl)acetamide chemical structure, C15H13FN6OS, CAS 587005-04-7
2-((4-Amino-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(4-fluorophenyl)acetamide
CAS 587005-04-7C15H13FN6OS
N-(4-Ethoxyphenyl)-2-{[4-(prop-2-en-1-yl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C20H21N5O2S, CAS 328020-64-0
N-(4-Ethoxyphenyl)-2-{[4-(prop-2-en-1-yl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide
CAS 328020-64-0C20H21N5O2S
N-(4-Methoxyphenyl)-2-{[4-(prop-2-en-1-yl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C19H19N5O2S, CAS 552814-36-5
N-(4-Methoxyphenyl)-2-{[4-(prop-2-en-1-yl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide
CAS 552814-36-5C19H19N5O2S
N-(2,6-Dimethylphenyl)-2-((4-ethyl-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl)sulfanyl)acetamide chemical structure, C19H21N5OS, CAS 482640-16-4
N-(2,6-Dimethylphenyl)-2-((4-ethyl-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl)sulfanyl)acetamide
CAS 482640-16-4C19H21N5OS
N-(4-BR-PH)-2-((4-Ethyl-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl)thio)acetamide chemical structure, C17H16BrN5OS, CAS 482640-17-5
N-(4-BR-PH)-2-((4-Ethyl-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl)thio)acetamide
CAS 482640-17-5C17H16BrN5OS
N-(2,3-Dichlorophenyl)-2-[(4-ethyl-5-pyridin-4-yl-1,2,4-triazol-3-yl)sulfanyl]acetamide chemical structure, C17H15Cl2N5OS, CAS 663213-79-4
N-(2,3-Dichlorophenyl)-2-[(4-ethyl-5-pyridin-4-yl-1,2,4-triazol-3-yl)sulfanyl]acetamide
CAS 663213-79-4C17H15Cl2N5OS
N-(4-Methoxyphenyl)-2-[(4-propyl-5-pyridin-4-yl-1,2,4-triazol-3-yl)sulfanyl]acetamide chemical structure, C19H21N5O2S, CAS 626209-81-2
N-(4-Methoxyphenyl)-2-[(4-propyl-5-pyridin-4-yl-1,2,4-triazol-3-yl)sulfanyl]acetamide
CAS 626209-81-2C19H21N5O2S