CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 20 atoms

35 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
35
With full pages
5
Scaffold SMILES

O=C(Nc1csc(-c2ccccc2)c1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1csc(-c2ccccc2)c1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 35 of 35 chemicals

Methyl 3-(2-methoxybenzamido)-5-phenylthiophene-2-carboxylate chemical structure, C20H17NO4S, CAS 406924-46-7
Methyl 3-(2-methoxybenzamido)-5-phenylthiophene-2-carboxylate
CAS 406924-46-7C20H17NO4S
Methyl 3-(4-methoxybenzamido)-5-phenylthiophene-2-carboxylate chemical structure, C20H17NO4S, CAS 406924-48-9
Methyl 3-(4-methoxybenzamido)-5-phenylthiophene-2-carboxylate
CAS 406924-48-9C20H17NO4S
Ethyl 3-(4-(N,N-dimethylsulfamoyl)benzamido)-5-phenylthiophene-2-carboxylate chemical structure, C22H22N2O5S2, CAS 380459-56-3
Ethyl 3-(4-(N,N-dimethylsulfamoyl)benzamido)-5-phenylthiophene-2-carboxylate
CAS 380459-56-3C22H22N2O5S2
Methyl 3-(3,5-dimethoxybenzamido)-5-phenylthiophene-2-carboxylate chemical structure, C21H19NO5S, CAS 477538-17-3
Methyl 3-(3,5-dimethoxybenzamido)-5-phenylthiophene-2-carboxylate
CAS 477538-17-3C21H19NO5S
Ethyl 3-(4-bromo-2-fluorobenzamido)-5-phenylthiophene-2-carboxylate chemical structure, C20H15BrFNO3S, CAS 392290-08-3
Ethyl 3-(4-bromo-2-fluorobenzamido)-5-phenylthiophene-2-carboxylate
CAS 392290-08-3C20H15BrFNO3S
Methyl 3-(4-fluorobenzamido)-5-phenylthiophene-2-carboxylate chemical structure, C19H14FNO3S, CAS 477326-28-6
Methyl 3-(4-fluorobenzamido)-5-phenylthiophene-2-carboxylate
CAS 477326-28-6C19H14FNO3S
Ethyl 3-(4-(N,N-bis(2-methoxyethyl)sulfamoyl)benzamido)-5-phenylthiophene-2-carboxylate chemical structure, C26H30N2O7S2, CAS 392290-16-3
Ethyl 3-(4-(N,N-bis(2-methoxyethyl)sulfamoyl)benzamido)-5-phenylthiophene-2-carboxylate
CAS 392290-16-3C26H30N2O7S2
Ethyl 3-(4-chlorobenzamido)-5-phenylthiophene-2-carboxylate chemical structure, C20H16ClNO3S, CAS 391867-53-1
Ethyl 3-(4-chlorobenzamido)-5-phenylthiophene-2-carboxylate
CAS 391867-53-1C20H16ClNO3S
Methyl 3-(2-chlorobenzamido)-5-phenylthiophene-2-carboxylate chemical structure, C19H14ClNO3S, CAS 477326-22-0
Methyl 3-(2-chlorobenzamido)-5-phenylthiophene-2-carboxylate
CAS 477326-22-0C19H14ClNO3S
Methyl 3-(2-iodobenzamido)-5-phenylthiophene-2-carboxylate chemical structure, C19H14INO3S, CAS 477326-72-0
Methyl 3-(2-iodobenzamido)-5-phenylthiophene-2-carboxylate
CAS 477326-72-0C19H14INO3S
Ethyl 3-(2-bromobenzamido)-5-phenylthiophene-2-carboxylate chemical structure, C20H16BrNO3S, CAS 476298-31-4
Ethyl 3-(2-bromobenzamido)-5-phenylthiophene-2-carboxylate
CAS 476298-31-4C20H16BrNO3S
Ethyl 5-phenyl-3-(3-(trifluoromethyl)benzamido)thiophene-2-carboxylate chemical structure, C21H16F3NO3S, CAS 392290-10-7
Ethyl 5-phenyl-3-(3-(trifluoromethyl)benzamido)thiophene-2-carboxylate
CAS 392290-10-7C21H16F3NO3S
Ethyl 3-(4-cyanobenzamido)-5-phenylthiophene-2-carboxylate chemical structure, C21H16N2O3S, CAS 391867-55-3
Ethyl 3-(4-cyanobenzamido)-5-phenylthiophene-2-carboxylate
CAS 391867-55-3C21H16N2O3S
Ethyl 5-phenyl-3-(3,4,5-trimethoxybenzamido)thiophene-2-carboxylate chemical structure, C23H23NO6S, CAS 391866-73-2
Ethyl 5-phenyl-3-(3,4,5-trimethoxybenzamido)thiophene-2-carboxylate
CAS 391866-73-2C23H23NO6S
Methyl 3-benzamido-5-phenylthiophene-2-carboxylate chemical structure, C19H15NO3S, CAS 101895-47-0
Methyl 3-benzamido-5-phenylthiophene-2-carboxylate
CAS 101895-47-0C19H15NO3S
Methyl 3-(2-nitrobenzamido)-5-phenylthiophene-2-carboxylate chemical structure, C19H14N2O5S, CAS 477326-25-3
Methyl 3-(2-nitrobenzamido)-5-phenylthiophene-2-carboxylate
CAS 477326-25-3C19H14N2O5S
Methyl 3-(2,3-dimethoxybenzamido)-5-phenylthiophene-2-carboxylate chemical structure, C21H19NO5S, CAS 922604-44-2
Methyl 3-(2,3-dimethoxybenzamido)-5-phenylthiophene-2-carboxylate
CAS 922604-44-2C21H19NO5S
Methyl 3-(3-(methylsulfonyl)benzamido)-5-phenylthiophene-2-carboxylate chemical structure, C20H17NO5S2, CAS 896290-61-2
Methyl 3-(3-(methylsulfonyl)benzamido)-5-phenylthiophene-2-carboxylate
CAS 896290-61-2C20H17NO5S2
Methyl 3-(2,6-difluorobenzamido)-5-(4-ethoxyphenyl)thiophene-2-carboxylate chemical structure, C21H17F2NO4S, CAS 890817-95-5
Methyl 3-(2,6-difluorobenzamido)-5-(4-ethoxyphenyl)thiophene-2-carboxylate
CAS 890817-95-5C21H17F2NO4S
Methyl 3-(4-chlorobenzamido)-5-phenylthiophene-2-carboxylate chemical structure, C19H14ClNO3S, CAS 477326-20-8
Methyl 3-(4-chlorobenzamido)-5-phenylthiophene-2-carboxylate
CAS 477326-20-8C19H14ClNO3S
Methyl 3-(3,4-dimethoxybenzamido)-5-phenylthiophene-2-carboxylate chemical structure, C21H19NO5S, CAS 477326-51-5
Methyl 3-(3,4-dimethoxybenzamido)-5-phenylthiophene-2-carboxylate
CAS 477326-51-5C21H19NO5S
Methyl 3-(4-methylbenzamido)-5-phenylthiophene-2-carboxylate chemical structure, C20H17NO3S, CAS 477326-18-4
Methyl 3-(4-methylbenzamido)-5-phenylthiophene-2-carboxylate
CAS 477326-18-4C20H17NO3S
3-[(2,6-Difluorobenzoyl)amino]-5-(4-ethoxyphenyl)thiophene-2-carboxylic acid chemical structure, C20H15F2NO4S, CAS 890818-51-6
3-[(2,6-Difluorobenzoyl)amino]-5-(4-ethoxyphenyl)thiophene-2-carboxylic acid
CAS 890818-51-6C20H15F2NO4S
Methyl 3-[4-(diethylsulfamoyl)benzamido]-5-phenylthiophene-2-carboxylate chemical structure, C23H24N2O5S2, CAS 477326-26-4
Methyl 3-[4-(diethylsulfamoyl)benzamido]-5-phenylthiophene-2-carboxylate
CAS 477326-26-4C23H24N2O5S2