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Murcko scaffold

4-Phenoxy-2-pyridin-2-ylquinazoline scaffold

7 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
23
Chemicals
7
With full pages
7
Scaffold SMILES

c1ccc(Oc2nc(-c3ccccn3)nc3ccccc23)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-Phenoxy-2-pyridin-2-ylquinazoline page
Murcko scaffold c1ccc(Oc2nc(-c3ccccn3)nc3ccccc23)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

4-(4-Methoxyphenoxy)-2-pyridin-2-ylquinazoline chemical structure, C20H15N3O2, CAS 799830-95-8
4-(4-Methoxyphenoxy)-2-pyridin-2-ylquinazoline
CAS 799830-95-8C20H15N3O2
4-(2-Methylphenoxy)-2-pyridin-2-ylquinazoline chemical structure, C20H15N3O, CAS 799832-03-4
4-(2-Methylphenoxy)-2-pyridin-2-ylquinazoline
CAS 799832-03-4C20H15N3O
4-(3-Methylphenoxy)-2-pyridin-2-ylquinazoline chemical structure, C20H15N3O, CAS 835907-67-0
4-(3-Methylphenoxy)-2-pyridin-2-ylquinazoline
CAS 835907-67-0C20H15N3O
4-(4-Fluorophenoxy)-2-pyridin-2-ylquinazoline chemical structure, C19H12FN3O, CAS 835909-09-6
4-(4-Fluorophenoxy)-2-pyridin-2-ylquinazoline
CAS 835909-09-6C19H12FN3O
4-Phenoxy-2-pyridin-2-ylquinazoline chemical structure, C19H13N3O, CAS 839701-05-2
4-Phenoxy-2-pyridin-2-ylquinazoline
CAS 839701-05-2C19H13N3O
N-[3-(2-Pyridin-2-ylquinazolin-4-yl)oxyphenyl]acetamide chemical structure, C21H16N4O2, CAS 799837-10-8
N-[3-(2-Pyridin-2-ylquinazolin-4-yl)oxyphenyl]acetamide
CAS 799837-10-8C21H16N4O2
N-[4-(2-Pyridin-2-ylquinazolin-4-yl)oxyphenyl]acetamide chemical structure, C21H16N4O2, CAS 578748-01-3
N-[4-(2-Pyridin-2-ylquinazolin-4-yl)oxyphenyl]acetamide
CAS 578748-01-3C21H16N4O2