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Murcko scaffold

Ring system with 4 rings and 23 atoms

6 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
23
Chemicals
6
With full pages
3
Scaffold SMILES

c1ccc(Nc2nc(-c3ccncc3)nc3ccccc23)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Nc2nc(-c3ccncc3)nc3ccccc23)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

N-(2,5-Dimethylphenyl)-2-pyridin-4-ylquinazolin-4-amine chemical structure, C21H18N4, CAS 6000-31-3
N-(2,5-Dimethylphenyl)-2-pyridin-4-ylquinazolin-4-amine
CAS 6000-31-3C21H18N4
N-(3,4-Difluorophenyl)-2-pyridin-4-ylquinazolin-4-amine chemical structure, C19H12F2N4, CAS 381168-77-0
N-(3,4-Difluorophenyl)-2-pyridin-4-ylquinazolin-4-amine
CAS 381168-77-0C19H12F2N4
Methyl 4-[(2-pyridin-4-ylquinazolin-4-yl)amino]benzoate chemical structure, C21H16N4O2, CAS 381703-10-2
Methyl 4-[(2-pyridin-4-ylquinazolin-4-yl)amino]benzoate
CAS 381703-10-2C21H16N4O2
(3-{[2-(Pyridin-4-yl)quinazolin-4-yl]amino}phenyl)methanol chemical structure, C20H16N4O, CAS 1011248-68-2
(3-{[2-(Pyridin-4-yl)quinazolin-4-yl]amino}phenyl)methanol
CAS 1011248-68-2C20H16N4O
3,5-Dichloro-N1-[2-(pyridin-4-yl)quinazolin-4-yl]benzene-1,4-diamine chemical structure, C19H13Cl2N5, CAS 1955553-82-8
3,5-Dichloro-N1-[2-(pyridin-4-yl)quinazolin-4-yl]benzene-1,4-diamine
CAS 1955553-82-8C19H13Cl2N5
33-BCRP Inhibitor chemical structure, C19H13N7, CAS 2953730-35-1
33-BCRP Inhibitor
CAS 2953730-35-1C19H13N7