CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 23 atoms

35 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
23
Chemicals
35
With full pages
2
Scaffold SMILES

c1ccc(Oc2nc(-c3ccccc3)nc3ccccc23)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Oc2nc(-c3ccccc3)nc3ccccc23)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 35 of 35 chemicals

2-(2-Fluorophenyl)-4-(4-methoxyphenoxy)quinazoline chemical structure, C21H15FN2O2, CAS 683807-49-0
2-(2-Fluorophenyl)-4-(4-methoxyphenoxy)quinazoline
CAS 683807-49-0C21H15FN2O2
Methyl 4-[(2-phenylquinazolin-4-yl)oxy]benzoate chemical structure, C22H16N2O3, CAS 379242-56-5
Methyl 4-[(2-phenylquinazolin-4-yl)oxy]benzoate
CAS 379242-56-5C22H16N2O3
4-(4-Chlorophenoxy)-2-(2-fluorophenyl)quinazoline chemical structure, C20H12ClFN2O, CAS 690689-28-2
4-(4-Chlorophenoxy)-2-(2-fluorophenyl)quinazoline
CAS 690689-28-2C20H12ClFN2O
4-(4-Chlorophenoxy)-2-(3-nitrophenyl)quinazoline chemical structure, C20H12ClN3O3, CAS 383892-73-7
4-(4-Chlorophenoxy)-2-(3-nitrophenyl)quinazoline
CAS 383892-73-7C20H12ClN3O3
Methyl 4-((2-(3-nitrophenyl)quinazolin-4-yl)oxy)benzoate chemical structure, C22H15N3O5, CAS 383894-60-8
Methyl 4-((2-(3-nitrophenyl)quinazolin-4-yl)oxy)benzoate
CAS 383894-60-8C22H15N3O5
2-[4-(2-Ethoxyphenoxy)quinazolin-1-ium-2-yl]phenolate chemical structure, C22H18N2O3, CAS 848730-41-6
2-[4-(2-Ethoxyphenoxy)quinazolin-1-ium-2-yl]phenolate
CAS 848730-41-6C22H18N2O3
2-[4-(4-Chloro-2,3-dimethylphenoxy)-2-quinazolinyl]phenol chemical structure, C22H17ClN2O2, CAS 847377-82-6
2-[4-(4-Chloro-2,3-dimethylphenoxy)-2-quinazolinyl]phenol
CAS 847377-82-6C22H17ClN2O2
4-Phenoxy-2-(4-propoxyphenyl)quinazoline chemical structure, C23H20N2O2, CAS 380563-64-4
4-Phenoxy-2-(4-propoxyphenyl)quinazoline
CAS 380563-64-4C23H20N2O2
2-[4-(2-Chloro-4-methylphenoxy)-2-quinazolinyl]phenol chemical structure, C21H15ClN2O2, CAS 848727-17-3
2-[4-(2-Chloro-4-methylphenoxy)-2-quinazolinyl]phenol
CAS 848727-17-3C21H15ClN2O2
2-[4-(4-Chloro-3-methylphenoxy)-2-quinazolinyl]phenol chemical structure, C21H15ClN2O2, CAS 845634-98-2
2-[4-(4-Chloro-3-methylphenoxy)-2-quinazolinyl]phenol
CAS 845634-98-2C21H15ClN2O2
2-[4-(2-Chloro-5-methylphenoxy)-2-quinazolinyl]phenol chemical structure, C21H15ClN2O2, CAS 848918-66-1
2-[4-(2-Chloro-5-methylphenoxy)-2-quinazolinyl]phenol
CAS 848918-66-1C21H15ClN2O2
Methyl 4-[2-(2-chlorophenyl)quinazolin-4-yl]oxybenzoate chemical structure, C22H15ClN2O3, CAS 354992-34-0
Methyl 4-[2-(2-chlorophenyl)quinazolin-4-yl]oxybenzoate
CAS 354992-34-0C22H15ClN2O3
Methyl 4-{[2-(3,4-dichlorophenyl)-4-quinazolinyl]oxy}benzoate chemical structure, C22H14Cl2N2O3, CAS 354992-35-1
Methyl 4-{[2-(3,4-dichlorophenyl)-4-quinazolinyl]oxy}benzoate
CAS 354992-35-1C22H14Cl2N2O3
4-(3,4-Dimethylphenoxy)-2-(2-fluorophenyl)quinazoline chemical structure, C22H17FN2O, CAS 690685-58-6
4-(3,4-Dimethylphenoxy)-2-(2-fluorophenyl)quinazoline
CAS 690685-58-6C22H17FN2O
N-[4-[2-(2-Fluorophenyl)quinazolin-4-yl]oxyphenyl]acetamide chemical structure, C22H16FN3O2, CAS 683807-50-3
N-[4-[2-(2-Fluorophenyl)quinazolin-4-yl]oxyphenyl]acetamide
CAS 683807-50-3C22H16FN3O2
Methyl 4-[2-(4-propoxyphenyl)quinazolin-4-yl]oxybenzoate chemical structure, C25H22N2O4, CAS 381174-10-3
Methyl 4-[2-(4-propoxyphenyl)quinazolin-4-yl]oxybenzoate
CAS 381174-10-3C25H22N2O4
Methyl 4-[2-(4-bromophenyl)quinazolin-4-yl]oxybenzoate chemical structure, C22H15BrN2O3, CAS 327097-32-5
Methyl 4-[2-(4-bromophenyl)quinazolin-4-yl]oxybenzoate
CAS 327097-32-5C22H15BrN2O3
2-[4-(4-Chloro-3,5-dimethylphenoxy)quinazolin-2-yl]phenol chemical structure, C22H17ClN2O2, CAS 4884-70-2
2-[4-(4-Chloro-3,5-dimethylphenoxy)quinazolin-2-yl]phenol
CAS 4884-70-2C22H17ClN2O2
2-[4-(2,3,5-Trimethylphenoxy)-2-quinazolinyl]phenol chemical structure, C23H20N2O2, CAS 843616-39-7
2-[4-(2,3,5-Trimethylphenoxy)-2-quinazolinyl]phenol
CAS 843616-39-7C23H20N2O2
2-{4-[2-Methoxy-4-(prop-2-en-1-yl)phenoxy]quinazolin-1-ium-2-yl}phenolate chemical structure, C24H20N2O3, CAS 848207-41-0
2-{4-[2-Methoxy-4-(prop-2-en-1-yl)phenoxy]quinazolin-1-ium-2-yl}phenolate
CAS 848207-41-0C24H20N2O3
2-[4-(2,3-Dichlorophenoxy)-2-quinazolinyl]phenol chemical structure, C20H12Cl2N2O2, CAS 848753-14-0
2-[4-(2,3-Dichlorophenoxy)-2-quinazolinyl]phenol
CAS 848753-14-0C20H12Cl2N2O2
4-(3,4-Dimethylphenoxy)-2-(4-fluorophenyl)quinazoline chemical structure, C22H17FN2O, CAS 496022-71-0
4-(3,4-Dimethylphenoxy)-2-(4-fluorophenyl)quinazoline
CAS 496022-71-0C22H17FN2O
4-(3,5-Dimethylphenoxy)-2-(2-fluorophenyl)quinazoline chemical structure, C22H17FN2O, CAS 690694-31-6
4-(3,5-Dimethylphenoxy)-2-(2-fluorophenyl)quinazoline
CAS 690694-31-6C22H17FN2O
N-[3-[2-(2-Fluorophenyl)quinazolin-4-yl]oxyphenyl]acetamide chemical structure, C22H16FN3O2, CAS 664971-43-1
N-[3-[2-(2-Fluorophenyl)quinazolin-4-yl]oxyphenyl]acetamide
CAS 664971-43-1C22H16FN3O2