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Murcko scaffold

Ring system with 4 rings and 23 atoms

10 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
23
Chemicals
10
With full pages
2
Scaffold SMILES

c1ccc(Nc2nc(-c3cccnc3)nc3ccccc23)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Nc2nc(-c3cccnc3)nc3ccccc23)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

N-(3-Methoxyphenyl)-2-(pyridin-3-yl)quinazolin-4-amine chemical structure, C20H16N4O, CAS 431073-31-3
N-(3-Methoxyphenyl)-2-(pyridin-3-yl)quinazolin-4-amine
CAS 431073-31-3C20H16N4O
N-(4-Methoxyphenyl)-2-pyridin-3-ylquinazolin-4-amine chemical structure, C20H16N4O, CAS 381683-52-9
N-(4-Methoxyphenyl)-2-pyridin-3-ylquinazolin-4-amine
CAS 381683-52-9C20H16N4O
N-(3,4-Difluorophenyl)-2-(pyridin-3-yl)quinazolin-4-amine chemical structure, C19H12F2N4, CAS 378219-91-1
N-(3,4-Difluorophenyl)-2-(pyridin-3-yl)quinazolin-4-amine
CAS 378219-91-1C19H12F2N4
N-(4-Ethoxyphenyl)-2-pyridin-3-ylquinazolin-4-amine chemical structure, C21H18N4O, CAS 385391-43-5
N-(4-Ethoxyphenyl)-2-pyridin-3-ylquinazolin-4-amine
CAS 385391-43-5C21H18N4O
N-(4-Iodophenyl)-2-(pyridin-3-yl)quinazolin-4-amine chemical structure, C19H13IN4, CAS 384795-52-2
N-(4-Iodophenyl)-2-(pyridin-3-yl)quinazolin-4-amine
CAS 384795-52-2C19H13IN4
Ethyl 4-((2-(pyridin-3-yl)quinazolin-4-yl)amino)benzoate chemical structure, C22H18N4O2, CAS 384369-91-9
Ethyl 4-((2-(pyridin-3-yl)quinazolin-4-yl)amino)benzoate
CAS 384369-91-9C22H18N4O2
1-(3-{[2-(Pyridin-3-yl)quinazolin-4-yl]amino}phenyl)ethan-1-one chemical structure, C21H16N4O, CAS 1118807-60-5
1-(3-{[2-(Pyridin-3-yl)quinazolin-4-yl]amino}phenyl)ethan-1-one
CAS 1118807-60-5C21H16N4O
(3-((2-(Pyridin-3-yl)quinazolin-4-yl)amino)phenyl)methanol chemical structure, C20H16N4O, CAS 1012938-57-6
(3-((2-(Pyridin-3-yl)quinazolin-4-yl)amino)phenyl)methanol
CAS 1012938-57-6C20H16N4O
N-(3-Chloro-4-fluorophenyl)-6-ethoxy-2-(pyridin-3-yl)quinazolin-4-amine chemical structure, C21H16ClFN4O, CAS 1314069-80-1
N-(3-Chloro-4-fluorophenyl)-6-ethoxy-2-(pyridin-3-yl)quinazolin-4-amine
CAS 1314069-80-1C21H16ClFN4O
2-[[7-Amino-2-(3-pyridinyl)-4-quinazolinyl]amino]benzamide chemical structure, C20H16N6O, CAS 1313911-20-4
2-[[7-Amino-2-(3-pyridinyl)-4-quinazolinyl]amino]benzamide
CAS 1313911-20-4C20H16N6O