CompoundList
Sign in
Murcko scaffold

(2-Phenylquinolin-4-yl)(piperidin-1-yl)methanone scaffold

48 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
48
With full pages
5
Scaffold SMILES

O=C(c1cc(-c2ccccc2)nc2ccccc12)N1CCCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the (2-Phenylquinolin-4-yl)(piperidin-1-yl)methanone page
Murcko scaffold O=C(c1cc(-c2ccccc2)nc2ccccc12)N1CCCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 48 chemicals

(3,5-Dimethylpiperidin-1-yl)(2-phenylquinolin-4-yl)methanone chemical structure, C23H24N2O, CAS 349414-84-2
(3,5-Dimethylpiperidin-1-yl)(2-phenylquinolin-4-yl)methanone
CAS 349414-84-2C23H24N2O
6-Methyl-2-phenyl-4-(1-piperidinylcarbonyl)quinoline chemical structure, C22H22N2O, CAS 303067-41-6
6-Methyl-2-phenyl-4-(1-piperidinylcarbonyl)quinoline
CAS 303067-41-6C22H22N2O
2-(4-Methylphenyl)-4-(1-piperidinylcarbonyl)quinoline chemical structure, C22H22N2O, CAS 362473-44-7
2-(4-Methylphenyl)-4-(1-piperidinylcarbonyl)quinoline
CAS 362473-44-7C22H22N2O
(3-Methyl-2-phenylquinolin-4-yl)-piperidin-1-ylmethanone chemical structure, C22H22N2O, CAS 487038-85-7
(3-Methyl-2-phenylquinolin-4-yl)-piperidin-1-ylmethanone
CAS 487038-85-7C22H22N2O
[6-Bromo-2-(3-methylphenyl)quinolin-4-yl]-(4-methylpiperidin-1-yl)methanone chemical structure, C23H23BrN2O, CAS 438214-01-8
[6-Bromo-2-(3-methylphenyl)quinolin-4-yl]-(4-methylpiperidin-1-yl)methanone
CAS 438214-01-8C23H23BrN2O
[6-Bromo-2-(4-ethoxyphenyl)quinolin-4-yl]-(4-methylpiperidin-1-yl)methanone chemical structure, C24H25BrN2O2, CAS 445234-44-6
[6-Bromo-2-(4-ethoxyphenyl)quinolin-4-yl]-(4-methylpiperidin-1-yl)methanone
CAS 445234-44-6C24H25BrN2O2
[2-(3,4-Dimethoxyphenyl)quinolin-4-yl]-(4-methylpiperidin-1-yl)methanone chemical structure, C24H26N2O3, CAS 354542-74-8
[2-(3,4-Dimethoxyphenyl)quinolin-4-yl]-(4-methylpiperidin-1-yl)methanone
CAS 354542-74-8C24H26N2O3
Methyl 1-(2-phenylquinoline-4-carbonyl)piperidine-4-carboxylate chemical structure, C23H22N2O3, CAS 349440-98-8
Methyl 1-(2-phenylquinoline-4-carbonyl)piperidine-4-carboxylate
CAS 349440-98-8C23H22N2O3
[2-(4-Chlorophenyl)-6-methylquinolin-4-yl]-piperidin-1-ylmethanone chemical structure, C22H21ClN2O, CAS 351425-44-0
[2-(4-Chlorophenyl)-6-methylquinolin-4-yl]-piperidin-1-ylmethanone
CAS 351425-44-0C22H21ClN2O
[2-(4-Bromophenyl)-8-methylquinolin-4-yl]-piperidin-1-ylmethanone chemical structure, C22H21BrN2O, CAS 355394-65-9
[2-(4-Bromophenyl)-8-methylquinolin-4-yl]-piperidin-1-ylmethanone
CAS 355394-65-9C22H21BrN2O
(7-Chloro-8-methyl-2-phenylquinolin-4-yl)-piperidin-1-ylmethanone chemical structure, C22H21ClN2O, CAS 669740-53-8
(7-Chloro-8-methyl-2-phenylquinolin-4-yl)-piperidin-1-ylmethanone
CAS 669740-53-8C22H21ClN2O
[2-(4-Ethoxyphenyl)quinolin-4-yl]-(4-methylpiperidin-1-yl)methanone chemical structure, C24H26N2O2, CAS 353476-99-0
[2-(4-Ethoxyphenyl)quinolin-4-yl]-(4-methylpiperidin-1-yl)methanone
CAS 353476-99-0C24H26N2O2
[2-(4-Bromophenyl)quinolin-4-yl]-piperidin-1-ylmethanone chemical structure, C21H19BrN2O, CAS 352689-55-5
[2-(4-Bromophenyl)quinolin-4-yl]-piperidin-1-ylmethanone
CAS 352689-55-5C21H19BrN2O
2-(2-Ethoxyphenyl)-4-(1-piperidinylcarbonyl)quinoline chemical structure, C23H24N2O2, CAS 444927-90-6
2-(2-Ethoxyphenyl)-4-(1-piperidinylcarbonyl)quinoline
CAS 444927-90-6C23H24N2O2
(8-Methyl-2-phenylquinolin-4-yl)-(4-methylpiperidin-1-yl)methanone chemical structure, C23H24N2O, CAS 588685-17-0
(8-Methyl-2-phenylquinolin-4-yl)-(4-methylpiperidin-1-yl)methanone
CAS 588685-17-0C23H24N2O
[8-Chloro-2-(2-methylphenyl)quinolin-4-yl]-(4-methylpiperidin-1-yl)methanone chemical structure, C23H23ClN2O, CAS 667440-10-0
[8-Chloro-2-(2-methylphenyl)quinolin-4-yl]-(4-methylpiperidin-1-yl)methanone
CAS 667440-10-0C23H23ClN2O
[2-(3,4-Dimethylphenyl)-8-methylquinolin-4-yl]-(4-methylpiperidin-1-yl)methanone chemical structure, C25H28N2O, CAS 669725-98-8
[2-(3,4-Dimethylphenyl)-8-methylquinolin-4-yl]-(4-methylpiperidin-1-yl)methanone
CAS 669725-98-8C25H28N2O
[2-(4-Chlorophenyl)-6,8-dimethylquinolin-4-yl]-piperidin-1-ylmethanone chemical structure, C23H23ClN2O, CAS 690225-61-7
[2-(4-Chlorophenyl)-6,8-dimethylquinolin-4-yl]-piperidin-1-ylmethanone
CAS 690225-61-7C23H23ClN2O
1-[2-(2-Chlorophenyl)quinoline-4-carbonyl]piperidine-4-carboxamide chemical structure, C22H20ClN3O2, CAS 732994-28-4
1-[2-(2-Chlorophenyl)quinoline-4-carbonyl]piperidine-4-carboxamide
CAS 732994-28-4C22H20ClN3O2
[2-(3,4-Dimethylphenyl)quinolin-4-yl]-(3,5-dimethylpiperidin-1-yl)methanone chemical structure, C25H28N2O, CAS 352677-65-7
[2-(3,4-Dimethylphenyl)quinolin-4-yl]-(3,5-dimethylpiperidin-1-yl)methanone
CAS 352677-65-7C25H28N2O
(2,6-Dimethylpiperidin-1-yl)[2-(2-methylphenyl)quinolin-4-yl]methanone chemical structure, C24H26N2O, CAS 549536-74-5
(2,6-Dimethylpiperidin-1-yl)[2-(2-methylphenyl)quinolin-4-yl]methanone
CAS 549536-74-5C24H26N2O
[2-(3,4-Dimethoxyphenyl)quinolin-4-yl]-(2-methylpiperidin-1-yl)methanone chemical structure, C24H26N2O3, CAS 354549-62-5
[2-(3,4-Dimethoxyphenyl)quinolin-4-yl]-(2-methylpiperidin-1-yl)methanone
CAS 354549-62-5C24H26N2O3
[2-(3-Methylphenyl)quinolin-4-yl]-(2-methylpiperidin-1-yl)methanone chemical structure, C23H24N2O, CAS 353476-96-7
[2-(3-Methylphenyl)quinolin-4-yl]-(2-methylpiperidin-1-yl)methanone
CAS 353476-96-7C23H24N2O
[2-(4-Chlorophenyl)quinolin-4-yl]-(3-methylpiperidin-1-yl)methanone chemical structure, C22H21ClN2O, CAS 352691-66-8
[2-(4-Chlorophenyl)quinolin-4-yl]-(3-methylpiperidin-1-yl)methanone
CAS 352691-66-8C22H21ClN2O