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Murcko scaffold

Morpholine, 4-[(2-phenyl-4-quinolinyl)carbonyl]- scaffold

30 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
30
With full pages
14
Scaffold SMILES

O=C(c1cc(-c2ccccc2)nc2ccccc12)N1CCOCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Morpholine, 4-[(2-phenyl-4-quinolinyl)carbonyl]- page
Murcko scaffold O=C(c1cc(-c2ccccc2)nc2ccccc12)N1CCOCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 30 of 30 chemicals

(6-Methyl-2-phenylquinolin-4-yl)-morpholin-4-ylmethanone chemical structure, C21H20N2O2, CAS 352673-56-4
(6-Methyl-2-phenylquinolin-4-yl)-morpholin-4-ylmethanone
CAS 352673-56-4C21H20N2O2
[6-Methyl-2-(4-methylphenyl)quinolin-4-yl]-morpholin-4-ylmethanone chemical structure, C22H22N2O2, CAS 351425-45-1
[6-Methyl-2-(4-methylphenyl)quinolin-4-yl]-morpholin-4-ylmethanone
CAS 351425-45-1C22H22N2O2
8-Methyl-4-(4-morpholinylcarbonyl)-2-phenylquinoline chemical structure, C21H20N2O2, CAS 351425-49-5
8-Methyl-4-(4-morpholinylcarbonyl)-2-phenylquinoline
CAS 351425-49-5C21H20N2O2
Morpholine, 4-[(2-phenyl-4-quinolinyl)carbonyl]- chemical structure, C20H18N2O2, CAS 88067-73-6
Morpholine, 4-[(2-phenyl-4-quinolinyl)carbonyl]-
CAS 88067-73-6C20H18N2O2
[2-(4-Methoxyphenyl)quinolin-4-yl]-morpholin-4-ylmethanone chemical structure, C21H20N2O3, CAS 355152-38-4
[2-(4-Methoxyphenyl)quinolin-4-yl]-morpholin-4-ylmethanone
CAS 355152-38-4C21H20N2O3
[2-(4-Methylphenyl)quinolin-4-yl]-morpholin-4-ylmethanone chemical structure, C21H20N2O2, CAS 317324-39-3
[2-(4-Methylphenyl)quinolin-4-yl]-morpholin-4-ylmethanone
CAS 317324-39-3C21H20N2O2
[2-(2-Methylphenyl)quinolin-4-yl]-morpholin-4-ylmethanone chemical structure, C21H20N2O2, CAS 353468-86-7
[2-(2-Methylphenyl)quinolin-4-yl]-morpholin-4-ylmethanone
CAS 353468-86-7C21H20N2O2
2-(2,4-Dimethylphenyl)-4-(4-morpholinylcarbonyl)quinoline chemical structure, C22H22N2O2, CAS 352688-03-0
2-(2,4-Dimethylphenyl)-4-(4-morpholinylcarbonyl)quinoline
CAS 352688-03-0C22H22N2O2
[2-(3-Methoxyphenyl)quinolin-4-yl]-morpholin-4-ylmethanone chemical structure, C21H20N2O3, CAS 541535-77-7
[2-(3-Methoxyphenyl)quinolin-4-yl]-morpholin-4-ylmethanone
CAS 541535-77-7C21H20N2O3
[2-(3-Methylphenyl)quinolin-4-yl]-morpholin-4-ylmethanone chemical structure, C21H20N2O2, CAS 438453-43-1
[2-(3-Methylphenyl)quinolin-4-yl]-morpholin-4-ylmethanone
CAS 438453-43-1C21H20N2O2
[8-Methyl-2-(4-methylphenyl)quinolin-4-yl]-morpholin-4-ylmethanone chemical structure, C22H22N2O2, CAS 355394-68-2
[8-Methyl-2-(4-methylphenyl)quinolin-4-yl]-morpholin-4-ylmethanone
CAS 355394-68-2C22H22N2O2
[2-(4-Ethylphenyl)quinolin-4-yl]-morpholin-4-ylmethanone chemical structure, C22H22N2O2, CAS 560080-59-3
[2-(4-Ethylphenyl)quinolin-4-yl]-morpholin-4-ylmethanone
CAS 560080-59-3C22H22N2O2
Morpholin-4-yl-[2-(3-propan-2-yloxyphenyl)quinolin-4-yl]methanone chemical structure, C23H24N2O3, CAS 495377-72-5
Morpholin-4-yl-[2-(3-propan-2-yloxyphenyl)quinolin-4-yl]methanone
CAS 495377-72-5C23H24N2O3
[2-[3-(2-Methylpropoxy)phenyl]quinolin-4-yl]-morpholin-4-ylmethanone chemical structure, C24H26N2O3, CAS 496017-05-1
[2-[3-(2-Methylpropoxy)phenyl]quinolin-4-yl]-morpholin-4-ylmethanone
CAS 496017-05-1C24H26N2O3
[6-Bromo-8-ethyl-2-(4-methoxyphenyl)quinolin-4-yl]-morpholin-4-ylmethanone chemical structure, C23H23BrN2O3, CAS 694465-79-7
[6-Bromo-8-ethyl-2-(4-methoxyphenyl)quinolin-4-yl]-morpholin-4-ylmethanone
CAS 694465-79-7C23H23BrN2O3
[2-(4-Chlorophenyl)-6,8-dimethylquinolin-4-yl]-morpholin-4-ylmethanone chemical structure, C22H21ClN2O2, CAS 690225-58-2
[2-(4-Chlorophenyl)-6,8-dimethylquinolin-4-yl]-morpholin-4-ylmethanone
CAS 690225-58-2C22H21ClN2O2
[2-(3-Chlorophenyl)-3,6,8-trimethylquinolin-4-yl]-morpholin-4-ylmethanone chemical structure, C23H23ClN2O2, CAS 690225-59-3
[2-(3-Chlorophenyl)-3,6,8-trimethylquinolin-4-yl]-morpholin-4-ylmethanone
CAS 690225-59-3C23H23ClN2O2
(7-Chloro-8-methyl-2-phenylquinolin-4-yl)-morpholin-4-ylmethanone chemical structure, C21H19ClN2O2, CAS 669738-42-5
(7-Chloro-8-methyl-2-phenylquinolin-4-yl)-morpholin-4-ylmethanone
CAS 669738-42-5C21H19ClN2O2
[2-(2-Chlorophenyl)quinolin-4-yl]-morpholin-4-ylmethanone chemical structure, C20H17ClN2O2, CAS 313393-31-6
[2-(2-Chlorophenyl)quinolin-4-yl]-morpholin-4-ylmethanone
CAS 313393-31-6C20H17ClN2O2
[2-(2,4-Dimethoxyphenyl)quinolin-4-yl]-morpholin-4-ylmethanone chemical structure, C22H22N2O4, CAS 352677-29-3
[2-(2,4-Dimethoxyphenyl)quinolin-4-yl]-morpholin-4-ylmethanone
CAS 352677-29-3C22H22N2O4
[2-(4-Chlorophenyl)quinolin-4-yl]-morpholin-4-ylmethanone chemical structure, C20H17ClN2O2, CAS 549537-07-7
[2-(4-Chlorophenyl)quinolin-4-yl]-morpholin-4-ylmethanone
CAS 549537-07-7C20H17ClN2O2
[2-(3-Bromophenyl)quinolin-4-yl]-morpholin-4-ylmethanone chemical structure, C20H17BrN2O2, CAS 5701-20-2
[2-(3-Bromophenyl)quinolin-4-yl]-morpholin-4-ylmethanone
CAS 5701-20-2C20H17BrN2O2
[6-Bromo-2-(4-propan-2-ylphenyl)quinolin-4-yl]-morpholin-4-ylmethanone chemical structure, C23H23BrN2O2, CAS 445031-32-3
[6-Bromo-2-(4-propan-2-ylphenyl)quinolin-4-yl]-morpholin-4-ylmethanone
CAS 445031-32-3C23H23BrN2O2
[2-(3-Bromophenyl)-6-methylquinolin-4-yl]-morpholin-4-ylmethanone chemical structure, C21H19BrN2O2, CAS 713118-04-8
[2-(3-Bromophenyl)-6-methylquinolin-4-yl]-morpholin-4-ylmethanone
CAS 713118-04-8C21H19BrN2O2