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Murcko scaffold

(4-Benzenesulfonyl-piperazin-1-yl)-furan-2-yl-methanone scaffold

52 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
52
With full pages
33
Scaffold SMILES

O=C(c1ccco1)N1CCN(S(=O)(=O)c2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the (4-Benzenesulfonyl-piperazin-1-yl)-furan-2-yl-methanone page
Murcko scaffold O=C(c1ccco1)N1CCN(S(=O)(=O)c2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 52 chemicals

1-(2-Furoyl)-4-[(3-nitrophenyl)sulfonyl]piperazine chemical structure, C15H15N3O6S, CAS 299922-52-4
1-(2-Furoyl)-4-[(3-nitrophenyl)sulfonyl]piperazine
CAS 299922-52-4C15H15N3O6S
1-[(3,4-Dimethylphenyl)sulfonyl]-4-(2-furoyl)piperazine chemical structure, C17H20N2O4S, CAS 681837-85-4
1-[(3,4-Dimethylphenyl)sulfonyl]-4-(2-furoyl)piperazine
CAS 681837-85-4C17H20N2O4S
[4-(2,4-Dimethylphenyl)sulfonylpiperazin-1-yl]-(furan-2-yl)methanone chemical structure, C17H20N2O4S, CAS 681837-90-1
[4-(2,4-Dimethylphenyl)sulfonylpiperazin-1-yl]-(furan-2-yl)methanone
CAS 681837-90-1C17H20N2O4S
(4-Benzenesulfonyl-piperazin-1-yl)-furan-2-yl-methanone chemical structure, C15H16N2O4S, CAS 328556-64-5
(4-Benzenesulfonyl-piperazin-1-yl)-furan-2-yl-methanone
CAS 328556-64-5C15H16N2O4S
1-(2-Fluorobenzenesulfonyl)-4-(furan-2-carbonyl)piperazine chemical structure, C15H15FN2O4S, CAS 670272-48-7
1-(2-Fluorobenzenesulfonyl)-4-(furan-2-carbonyl)piperazine
CAS 670272-48-7C15H15FN2O4S
1-(2-Furoyl)-4-[(2,3,5,6-tetramethylphenyl)sulfonyl]piperazine chemical structure, C19H24N2O4S, CAS 438228-10-5
1-(2-Furoyl)-4-[(2,3,5,6-tetramethylphenyl)sulfonyl]piperazine
CAS 438228-10-5C19H24N2O4S
Furan-2-yl-[4-(4-methoxyphenyl)sulfonylpiperazin-1-yl]methanone chemical structure, C16H18N2O5S, CAS 461398-47-0
Furan-2-yl-[4-(4-methoxyphenyl)sulfonylpiperazin-1-yl]methanone
CAS 461398-47-0C16H18N2O5S
[4-(2,5-Dimethoxy-benzenesulfonyl)-piperazin-1-yl]-furan-2-yl-methanone chemical structure, C17H20N2O6S, CAS 438227-71-5
[4-(2,5-Dimethoxy-benzenesulfonyl)-piperazin-1-yl]-furan-2-yl-methanone
CAS 438227-71-5C17H20N2O6S
[4-(4-Chloro-benzenesulfonyl)-piperazin-1-yl]-furan-2-yl-methanone chemical structure, C15H15ClN2O4S, CAS 333756-57-3
[4-(4-Chloro-benzenesulfonyl)-piperazin-1-yl]-furan-2-yl-methanone
CAS 333756-57-3C15H15ClN2O4S
[4-(2,5-Dichlorophenyl)sulfonylpiperazin-1-yl]-(furan-2-yl)methanone chemical structure, C15H14Cl2N2O4S, CAS 697770-79-9
[4-(2,5-Dichlorophenyl)sulfonylpiperazin-1-yl]-(furan-2-yl)methanone
CAS 697770-79-9C15H14Cl2N2O4S
2-Furyl 4-[(4-iodophenyl)sulfonyl]piperazinyl ketone chemical structure, C15H15IN2O4S, CAS 727420-14-6
2-Furyl 4-[(4-iodophenyl)sulfonyl]piperazinyl ketone
CAS 727420-14-6C15H15IN2O4S
1-[(5-Chloro-2-methoxyphenyl)sulfonyl]-4-(2-furoyl)piperazine chemical structure, C16H17ClN2O5S, CAS 97629-81-7
1-[(5-Chloro-2-methoxyphenyl)sulfonyl]-4-(2-furoyl)piperazine
CAS 97629-81-7C16H17ClN2O5S
1-[(2-Ethoxy-5-isopropylphenyl)sulfonyl]-4-(2-furoyl)piperazine chemical structure, C20H26N2O5S, CAS 794548-62-2
1-[(2-Ethoxy-5-isopropylphenyl)sulfonyl]-4-(2-furoyl)piperazine
CAS 794548-62-2C20H26N2O5S
1-[(4-Ethoxyphenyl)sulfonyl]-4-(2-furoyl)piperazine chemical structure, C17H20N2O5S, CAS 438224-20-5
1-[(4-Ethoxyphenyl)sulfonyl]-4-(2-furoyl)piperazine
CAS 438224-20-5C17H20N2O5S
Furan-2-yl-[4-(3-methoxyphenyl)sulfonylpiperazin-1-yl]methanone chemical structure, C16H18N2O5S, CAS 670272-52-3
Furan-2-yl-[4-(3-methoxyphenyl)sulfonylpiperazin-1-yl]methanone
CAS 670272-52-3C16H18N2O5S
(4-((2,5-Dimethylphenyl)sulfonyl)piperazin-1-yl)(furan-2-yl)methanone chemical structure, C17H20N2O4S, CAS 671200-93-4
(4-((2,5-Dimethylphenyl)sulfonyl)piperazin-1-yl)(furan-2-yl)methanone
CAS 671200-93-4C17H20N2O4S
1-(2-Furoyl)-4-{[3-(trifluoromethyl)phenyl]sulfonyl}piperazine chemical structure, C16H15F3N2O4S, CAS 670272-47-6
1-(2-Furoyl)-4-{[3-(trifluoromethyl)phenyl]sulfonyl}piperazine
CAS 670272-47-6C16H15F3N2O4S
1-[(2,6-Dichlorophenyl)sulfonyl]-4-(2-furoyl)piperazine chemical structure, C15H14Cl2N2O4S, CAS 670272-49-8
1-[(2,6-Dichlorophenyl)sulfonyl]-4-(2-furoyl)piperazine
CAS 670272-49-8C15H14Cl2N2O4S
1-[(3-Chlorophenyl)sulfonyl]-4-(2-furoyl)piperazine chemical structure, C15H15ClN2O4S, CAS 670272-50-1
1-[(3-Chlorophenyl)sulfonyl]-4-(2-furoyl)piperazine
CAS 670272-50-1C15H15ClN2O4S
1-[(3,4-Dimethoxyphenyl)sulfonyl]-4-(2-furoyl)piperazine chemical structure, C17H20N2O6S, CAS 693270-77-8
1-[(3,4-Dimethoxyphenyl)sulfonyl]-4-(2-furoyl)piperazine
CAS 693270-77-8C17H20N2O6S
Piperazine, 1-((4-chloro-3-(trifluoromethyl)phenyl)sulfonyl)-4-(2-furanylcarbonyl)- chemical structure, C16H14ClF3N2O4S, CAS 97629-82-8
Piperazine, 1-((4-chloro-3-(trifluoromethyl)phenyl)sulfonyl)-4-(2-furanylcarbonyl)-
CAS 97629-82-8C16H14ClF3N2O4S
2-Furyl 4-((2-nitrophenyl)sulfonyl)piperazinyl ketone chemical structure, C15H15N3O6S, CAS 428502-54-9
2-Furyl 4-((2-nitrophenyl)sulfonyl)piperazinyl ketone
CAS 428502-54-9C15H15N3O6S
1-[(5-Fluoro-2-methoxyphenyl)sulfonyl]-4-(2-furoyl)piperazine chemical structure, C16H17FN2O5S, CAS 727420-13-5
1-[(5-Fluoro-2-methoxyphenyl)sulfonyl]-4-(2-furoyl)piperazine
CAS 727420-13-5C16H17FN2O5S
1-(2-Furoyl)-4-[(4-methylphenyl)sulfonyl]piperazine chemical structure, C16H18N2O4S, CAS 313250-89-4
1-(2-Furoyl)-4-[(4-methylphenyl)sulfonyl]piperazine
CAS 313250-89-4C16H18N2O4S