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Murcko scaffold

1-Benzyl-4-(furan-2-ylmethyl)piperazine scaffold

27 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
27
With full pages
8
Scaffold SMILES

c1ccc(CN2CCN(Cc3ccco3)CC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-Benzyl-4-(furan-2-ylmethyl)piperazine page
Murcko scaffold c1ccc(CN2CCN(Cc3ccco3)CC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 27 of 27 chemicals

1-(2-Bromobenzyl)-4-(2-furylmethyl)piperazine chemical structure, C16H19BrN2O, CAS 438482-42-9
1-(2-Bromobenzyl)-4-(2-furylmethyl)piperazine
CAS 438482-42-9C16H19BrN2O
1-(Furan-2-ylmethyl)-4-[(4-nitrophenyl)methyl]piperazine chemical structure, C16H19N3O3, CAS 356082-87-6
1-(Furan-2-ylmethyl)-4-[(4-nitrophenyl)methyl]piperazine
CAS 356082-87-6C16H19N3O3
1-(2-Furylmethyl)-4-(3-nitrobenzyl)piperazine chemical structure, C16H19N3O3, CAS 5882-37-1
1-(2-Furylmethyl)-4-(3-nitrobenzyl)piperazine
CAS 5882-37-1C16H19N3O3
1-[(3-Bromophenyl)methyl]-4-(furan-2-ylmethyl)piperazine chemical structure, C16H19BrN2O, CAS 356084-84-9
1-[(3-Bromophenyl)methyl]-4-(furan-2-ylmethyl)piperazine
CAS 356084-84-9C16H19BrN2O
1-(Furan-2-ylmethyl)-4-[(4-methylsulfanylphenyl)methyl]piperazine chemical structure, C17H22N2OS, CAS 356085-07-9
1-(Furan-2-ylmethyl)-4-[(4-methylsulfanylphenyl)methyl]piperazine
CAS 356085-07-9C17H22N2OS
1-Benzyl-4-(furan-2-ylmethyl)piperazine chemical structure, C16H20N2O, CAS 266674-68-4
1-Benzyl-4-(furan-2-ylmethyl)piperazine
CAS 266674-68-4C16H20N2O
1-[(3-Ethoxy-4-methoxyphenyl)methyl]-4-(furan-2-ylmethyl)piperazine chemical structure, C19H26N2O3, CAS 428841-62-7
1-[(3-Ethoxy-4-methoxyphenyl)methyl]-4-(furan-2-ylmethyl)piperazine
CAS 428841-62-7C19H26N2O3
4-[[4-(Furan-2-ylmethyl)piperazin-1-yl]methyl]-2,6-dimethoxyphenol chemical structure, C18H24N2O4, CAS 461397-42-2
4-[[4-(Furan-2-ylmethyl)piperazin-1-yl]methyl]-2,6-dimethoxyphenol
CAS 461397-42-2C18H24N2O4
1-[(4-Bromophenyl)methyl]-4-(furan-2-ylmethyl)piperazine chemical structure, C16H19BrN2O, CAS 356084-00-9
1-[(4-Bromophenyl)methyl]-4-(furan-2-ylmethyl)piperazine
CAS 356084-00-9C16H19BrN2O
1-(Furan-2-ylmethyl)-4-[(4-methoxyphenyl)methyl]piperazine chemical structure, C17H22N2O2, CAS 356086-25-4
1-(Furan-2-ylmethyl)-4-[(4-methoxyphenyl)methyl]piperazine
CAS 356086-25-4C17H22N2O2
1-(Furan-2-ylmethyl)-4-[4-(trifluoromethyl)benzyl]piperazine chemical structure, C17H19F3N2O, CAS 355822-72-9
1-(Furan-2-ylmethyl)-4-[4-(trifluoromethyl)benzyl]piperazine
CAS 355822-72-9C17H19F3N2O
1-(Furan-2-ylmethyl)-4-[(3,4,5-trimethoxyphenyl)methyl]piperazine chemical structure, C19H26N2O4, CAS 355822-81-0
1-(Furan-2-ylmethyl)-4-[(3,4,5-trimethoxyphenyl)methyl]piperazine
CAS 355822-81-0C19H26N2O4
1-(Furan-2-ylmethyl)-4-[(2,4,5-trimethoxyphenyl)methyl]piperazine chemical structure, C19H26N2O4, CAS 355822-95-6
1-(Furan-2-ylmethyl)-4-[(2,4,5-trimethoxyphenyl)methyl]piperazine
CAS 355822-95-6C19H26N2O4
1-[(2,4-Dimethoxyphenyl)methyl]-4-(furan-2-ylmethyl)piperazine chemical structure, C18H24N2O3, CAS 355823-07-3
1-[(2,4-Dimethoxyphenyl)methyl]-4-(furan-2-ylmethyl)piperazine
CAS 355823-07-3C18H24N2O3
1-[(2,5-Dimethoxyphenyl)methyl]-4-(furan-2-ylmethyl)piperazine chemical structure, C18H24N2O3, CAS 355823-74-4
1-[(2,5-Dimethoxyphenyl)methyl]-4-(furan-2-ylmethyl)piperazine
CAS 355823-74-4C18H24N2O3
1-(2-Furylmethyl)-4-(2,3,4-trimethoxybenzyl)piperazine chemical structure, C19H26N2O4, CAS 423155-05-9
1-(2-Furylmethyl)-4-(2,3,4-trimethoxybenzyl)piperazine
CAS 423155-05-9C19H26N2O4
1-(Furan-2-ylmethyl)-4-[(4-methylphenyl)methyl]piperazine chemical structure, C17H22N2O, CAS 438486-57-8
1-(Furan-2-ylmethyl)-4-[(4-methylphenyl)methyl]piperazine
CAS 438486-57-8C17H22N2O
1-[(2,3-Dimethoxyphenyl)methyl]-4-(furan-2-ylmethyl)piperazine chemical structure, C18H24N2O3, CAS 355818-36-9
1-[(2,3-Dimethoxyphenyl)methyl]-4-(furan-2-ylmethyl)piperazine
CAS 355818-36-9C18H24N2O3
1-[(3,4-Dimethoxyphenyl)methyl]-4-(furan-2-ylmethyl)piperazine chemical structure, C18H24N2O3, CAS 355818-67-6
1-[(3,4-Dimethoxyphenyl)methyl]-4-(furan-2-ylmethyl)piperazine
CAS 355818-67-6C18H24N2O3
1-[(3,5-Dimethoxyphenyl)methyl]-4-(furan-2-ylmethyl)piperazine chemical structure, C18H24N2O3, CAS 355818-79-0
1-[(3,5-Dimethoxyphenyl)methyl]-4-(furan-2-ylmethyl)piperazine
CAS 355818-79-0C18H24N2O3
1-(Furan-2-ylmethyl)-4-[(3-methylphenyl)methyl]piperazine chemical structure, C17H22N2O, CAS 355820-72-3
1-(Furan-2-ylmethyl)-4-[(3-methylphenyl)methyl]piperazine
CAS 355820-72-3C17H22N2O
1-[(4-Ethylphenyl)methyl]-4-(furan-2-ylmethyl)piperazine chemical structure, C18H24N2O, CAS 461422-49-1
1-[(4-Ethylphenyl)methyl]-4-(furan-2-ylmethyl)piperazine
CAS 461422-49-1C18H24N2O
1-[(4,5-Dimethoxy-2-nitrophenyl)methyl]-4-(furan-2-ylmethyl)piperazine chemical structure, C18H23N3O5, CAS 355821-44-2
1-[(4,5-Dimethoxy-2-nitrophenyl)methyl]-4-(furan-2-ylmethyl)piperazine
CAS 355821-44-2C18H23N3O5
4-Bromo-2-{[4-(furan-2-ylmethyl)piperazin-1-yl]methyl}phenol chemical structure, C16H19BrN2O2, CAS 424811-19-8
4-Bromo-2-{[4-(furan-2-ylmethyl)piperazin-1-yl]methyl}phenol
CAS 424811-19-8C16H19BrN2O2