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Murcko scaffold

Ring system with 3 rings and 21 atoms

6 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
6
With full pages
4
Scaffold SMILES

c1ccc(COc2ccc(Cc3cncnc3)cc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(COc2ccc(Cc3cncnc3)cc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

2,4-Pyrimidinediamine, 5-((3-methoxy-4-(phenylmethoxy)phenyl)methyl)- chemical structure, C19H20N4O2, CAS 83158-06-9
2,4-Pyrimidinediamine, 5-((3-methoxy-4-(phenylmethoxy)phenyl)methyl)-
CAS 83158-06-9C19H20N4O2
5-[(4-Benzyloxy)benzyl]-2,4-diaminopyrimidine chemical structure, C18H18N4O, CAS 49873-11-2
5-[(4-Benzyloxy)benzyl]-2,4-diaminopyrimidine
CAS 49873-11-2C18H18N4O
5-(4-Benzyloxy-3,5-dimethoxy-benzyl)-pyrimidine-2,4-diamine chemical structure, C20H22N4O3, CAS 21822-34-4
5-(4-Benzyloxy-3,5-dimethoxy-benzyl)-pyrimidine-2,4-diamine
CAS 21822-34-4C20H22N4O3
5-(4-(Benzyloxy)-3-ethoxybenzyl)pyrimidine-2,4-diamine chemical structure, C20H22N4O2, CAS 98612-08-9
5-(4-(Benzyloxy)-3-ethoxybenzyl)pyrimidine-2,4-diamine
CAS 98612-08-9C20H22N4O2
GW-2580 chemical structure, C20H22N4O3, CAS 870483-87-7
GW-2580
CAS 870483-87-7C20H22N4O3
5-[[3-(Trideuteriomethoxy)-4-[[4-(trideuteriomethoxy)phenyl]methoxy]phenyl]methyl]pyrimidine-2,4-diamine chemical structure, C20H22N4O3, CAS 2733770-48-2
5-[[3-(Trideuteriomethoxy)-4-[[4-(trideuteriomethoxy)phenyl]methoxy]phenyl]methyl]pyrimidine-2,4-diamine
CAS 2733770-48-2C20H22N4O3