CompoundList
Sign in
Murcko scaffold

Ring system with 2 rings and 16 atoms

29 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
16
Chemicals
29
With full pages
8
Scaffold SMILES

O=C(CSc1ncns1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CSc1ncns1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 29 of 29 chemicals

N-(3-Acetylphenyl)-2-[(3-methylsulfanyl-1,2,4-thiadiazol-5-yl)sulfanyl]acetamide chemical structure, C13H13N3O2S3, CAS 825610-61-5
N-(3-Acetylphenyl)-2-[(3-methylsulfanyl-1,2,4-thiadiazol-5-yl)sulfanyl]acetamide
CAS 825610-61-5C13H13N3O2S3
N-(4-Fluorophenyl)-2-[(3-methylsulfanyl-1,2,4-thiadiazol-5-yl)sulfanyl]acetamide chemical structure, C11H10FN3OS3, CAS 511276-56-5
N-(4-Fluorophenyl)-2-[(3-methylsulfanyl-1,2,4-thiadiazol-5-yl)sulfanyl]acetamide
CAS 511276-56-5C11H10FN3OS3
N-(2-Methoxyphenyl)-2-[(3-methylsulfanyl-1,2,4-thiadiazol-5-yl)sulfanyl]acetamide chemical structure, C12H13N3O2S3, CAS 511276-15-6
N-(2-Methoxyphenyl)-2-[(3-methylsulfanyl-1,2,4-thiadiazol-5-yl)sulfanyl]acetamide
CAS 511276-15-6C12H13N3O2S3
Ethyl 4-[({[3-(methylthio)-1,2,4-thiadiazol-5-yl]thio}acetyl)amino]benzoate chemical structure, C14H15N3O3S3, CAS 713506-64-0
Ethyl 4-[({[3-(methylthio)-1,2,4-thiadiazol-5-yl]thio}acetyl)amino]benzoate
CAS 713506-64-0C14H15N3O3S3
N-(4-Acetylphenyl)-2-[(3-methylsulfanyl-1,2,4-thiadiazol-5-yl)sulfanyl]acetamide chemical structure, C13H13N3O2S3, CAS 511275-92-6
N-(4-Acetylphenyl)-2-[(3-methylsulfanyl-1,2,4-thiadiazol-5-yl)sulfanyl]acetamide
CAS 511275-92-6C13H13N3O2S3
Ethyl 4-[(2-{[3-(methylsulfanyl)-1,2,4-thiadiazol-5-yl]sulfanyl}butanoyl)amino]benzoate chemical structure, C16H19N3O3S3, CAS 713080-82-1
Ethyl 4-[(2-{[3-(methylsulfanyl)-1,2,4-thiadiazol-5-yl]sulfanyl}butanoyl)amino]benzoate
CAS 713080-82-1C16H19N3O3S3
N-(4-Iodophenyl)-2-{[3-(methylsulfanyl)-1,2,4-thiadiazol-5-yl]sulfanyl}acetamide chemical structure, C11H10IN3OS3, CAS 825610-83-1
N-(4-Iodophenyl)-2-{[3-(methylsulfanyl)-1,2,4-thiadiazol-5-yl]sulfanyl}acetamide
CAS 825610-83-1C11H10IN3OS3
N-(4-Bromo-2-fluorophenyl)-2-{[3-(methylsulfanyl)-1,2,4-thiadiazol-5-yl]sulfanyl}acetamide chemical structure, C11H9BrFN3OS3, CAS 825610-60-4
N-(4-Bromo-2-fluorophenyl)-2-{[3-(methylsulfanyl)-1,2,4-thiadiazol-5-yl]sulfanyl}acetamide
CAS 825610-60-4C11H9BrFN3OS3
2-{[3-(Methylsulfanyl)-1,2,4-thiadiazol-5-yl]sulfanyl}-N-[3-(trifluoromethyl)phenyl]acetamide chemical structure, C12H10F3N3OS3, CAS 511276-24-7
2-{[3-(Methylsulfanyl)-1,2,4-thiadiazol-5-yl]sulfanyl}-N-[3-(trifluoromethyl)phenyl]acetamide
CAS 511276-24-7C12H10F3N3OS3
N-(4-Cyanophenyl)-2-[(3-methylsulfanyl-1,2,4-thiadiazol-5-yl)sulfanyl]acetamide chemical structure, C12H10N4OS3, CAS 511276-53-2
N-(4-Cyanophenyl)-2-[(3-methylsulfanyl-1,2,4-thiadiazol-5-yl)sulfanyl]acetamide
CAS 511276-53-2C12H10N4OS3
N-(3,4-Difluorophenyl)-2-[(3-methylsulfanyl-1,2,4-thiadiazol-5-yl)sulfanyl]acetamide chemical structure, C11H9F2N3OS3, CAS 878417-77-7
N-(3,4-Difluorophenyl)-2-[(3-methylsulfanyl-1,2,4-thiadiazol-5-yl)sulfanyl]acetamide
CAS 878417-77-7C11H9F2N3OS3
N-(3-Chloro-4-fluorophenyl)-2-[(3-methylsulfanyl-1,2,4-thiadiazol-5-yl)sulfanyl]acetamide chemical structure, C11H9ClFN3OS3, CAS 511276-17-8
N-(3-Chloro-4-fluorophenyl)-2-[(3-methylsulfanyl-1,2,4-thiadiazol-5-yl)sulfanyl]acetamide
CAS 511276-17-8C11H9ClFN3OS3
N-(3,4-Dichlorophenyl)-2-[(3-methylsulfanyl-1,2,4-thiadiazol-5-yl)sulfanyl]acetamide chemical structure, C11H9Cl2N3OS3, CAS 511275-87-9
N-(3,4-Dichlorophenyl)-2-[(3-methylsulfanyl-1,2,4-thiadiazol-5-yl)sulfanyl]acetamide
CAS 511275-87-9C11H9Cl2N3OS3
4-[({[3-(Methylsulfanyl)-1,2,4-thiadiazol-5-yl]sulfanyl}acetyl)amino]benzoic acid chemical structure, C12H11N3O3S3, CAS 511276-55-4
4-[({[3-(Methylsulfanyl)-1,2,4-thiadiazol-5-yl]sulfanyl}acetyl)amino]benzoic acid
CAS 511276-55-4C12H11N3O3S3
N-(3-Methoxyphenyl)-2-[(3-methylsulfanyl-1,2,4-thiadiazol-5-yl)sulfanyl]acetamide chemical structure, C12H13N3O2S3, CAS 511275-91-5
N-(3-Methoxyphenyl)-2-[(3-methylsulfanyl-1,2,4-thiadiazol-5-yl)sulfanyl]acetamide
CAS 511275-91-5C12H13N3O2S3
2-[({[3-(Methylsulfanyl)-1,2,4-thiadiazol-5-yl]sulfanyl}acetyl)amino]benzoic acid chemical structure, C12H11N3O3S3, CAS 511276-54-3
2-[({[3-(Methylsulfanyl)-1,2,4-thiadiazol-5-yl]sulfanyl}acetyl)amino]benzoic acid
CAS 511276-54-3C12H11N3O3S3
N-(4-Acetamidophenyl)-2-[(3-methylsulfanyl-1,2,4-thiadiazol-5-yl)sulfanyl]acetamide chemical structure, C13H14N4O2S3, CAS 511275-89-1
N-(4-Acetamidophenyl)-2-[(3-methylsulfanyl-1,2,4-thiadiazol-5-yl)sulfanyl]acetamide
CAS 511275-89-1C13H14N4O2S3
N-(2,5-Dimethoxyphenyl)-2-{[3-(methylsulfanyl)-1,2,4-thiadiazol-5-yl]sulfanyl}acetamide chemical structure, C13H15N3O3S3, CAS 511276-36-1
N-(2,5-Dimethoxyphenyl)-2-{[3-(methylsulfanyl)-1,2,4-thiadiazol-5-yl]sulfanyl}acetamide
CAS 511276-36-1C13H15N3O3S3
N-(2-Fluorophenyl)-2-[(3-methylsulfanyl-1,2,4-thiadiazol-5-yl)sulfanyl]acetamide chemical structure, C11H10FN3OS3, CAS 511276-01-0
N-(2-Fluorophenyl)-2-[(3-methylsulfanyl-1,2,4-thiadiazol-5-yl)sulfanyl]acetamide
CAS 511276-01-0C11H10FN3OS3
N-(4-Chlorophenyl)-2-[(3-methylsulfanyl-1,2,4-thiadiazol-5-yl)sulfanyl]acetamide chemical structure, C11H10ClN3OS3, CAS 511276-16-7
N-(4-Chlorophenyl)-2-[(3-methylsulfanyl-1,2,4-thiadiazol-5-yl)sulfanyl]acetamide
CAS 511276-16-7C11H10ClN3OS3
3-[({[3-(Methylsulfanyl)-1,2,4-thiadiazol-5-yl]sulfanyl}acetyl)amino]benzoic acid chemical structure, C12H11N3O3S3, CAS 511276-67-8
3-[({[3-(Methylsulfanyl)-1,2,4-thiadiazol-5-yl]sulfanyl}acetyl)amino]benzoic acid
CAS 511276-67-8C12H11N3O3S3
N-(4-Methoxyphenyl)-2-[(3-methylsulfanyl-1,2,4-thiadiazol-5-yl)sulfanyl]acetamide chemical structure, C12H13N3O2S3, CAS 511275-88-0
N-(4-Methoxyphenyl)-2-[(3-methylsulfanyl-1,2,4-thiadiazol-5-yl)sulfanyl]acetamide
CAS 511275-88-0C12H13N3O2S3
N-(5-Chloro-2,4-dimethoxyphenyl)-2-[(3-methylsulfanyl-1,2,4-thiadiazol-5-yl)sulfanyl]acetamide chemical structure, C13H14ClN3O3S3, CAS 893634-27-0
N-(5-Chloro-2,4-dimethoxyphenyl)-2-[(3-methylsulfanyl-1,2,4-thiadiazol-5-yl)sulfanyl]acetamide
CAS 893634-27-0C13H14ClN3O3S3
N-(2-Cyanophenyl)-2-[(3-methylsulfanyl-1,2,4-thiadiazol-5-yl)sulfanyl]acetamide chemical structure, C12H10N4OS3, CAS 878417-61-9
N-(2-Cyanophenyl)-2-[(3-methylsulfanyl-1,2,4-thiadiazol-5-yl)sulfanyl]acetamide
CAS 878417-61-9C12H10N4OS3