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Murcko scaffold

Ring system with 3 rings and 19 atoms

12 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
12
With full pages
5
Scaffold SMILES

c1ccc(CCc2nc(-c3ccccc3)no2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(CCc2nc(-c3ccccc3)no2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

3-(3-Nitrophenyl)-5-(2-phenylethyl)-1,2,4-oxadiazole chemical structure, C16H13N3O3, CAS 6136-89-6
3-(3-Nitrophenyl)-5-(2-phenylethyl)-1,2,4-oxadiazole
CAS 6136-89-6C16H13N3O3
3-(4-Nitrophenyl)-5-(2-phenylethyl)-1,2,4-oxadiazole chemical structure, C16H13N3O3, CAS 381714-31-4
3-(4-Nitrophenyl)-5-(2-phenylethyl)-1,2,4-oxadiazole
CAS 381714-31-4C16H13N3O3
3-(4-Chlorophenyl)-5-(2-phenylethyl)-1,2,4-oxadiazole chemical structure, C16H13ClN2O, CAS 21614-50-6
3-(4-Chlorophenyl)-5-(2-phenylethyl)-1,2,4-oxadiazole
CAS 21614-50-6C16H13ClN2O
3-(4-Methylphenyl)-5-(2-phenylethyl)-1,2,4-oxadiazole chemical structure, C17H16N2O, CAS 381708-96-9
3-(4-Methylphenyl)-5-(2-phenylethyl)-1,2,4-oxadiazole
CAS 381708-96-9C17H16N2O
3-(4-Methoxyphenyl)-5-(2-phenylethyl)-1,2,4-oxadiazole chemical structure, C17H16N2O2, CAS 442571-89-3
3-(4-Methoxyphenyl)-5-(2-phenylethyl)-1,2,4-oxadiazole
CAS 442571-89-3C17H16N2O2
3-(4-Bromophenyl)-5-(2-phenylethyl)-1,2,4-oxadiazole chemical structure, C16H13BrN2O, CAS 693242-36-3
3-(4-Bromophenyl)-5-(2-phenylethyl)-1,2,4-oxadiazole
CAS 693242-36-3C16H13BrN2O
3-(3-Methoxyphenyl)-5-(2-phenylethyl)-1,2,4-oxadiazole chemical structure, C17H16N2O2, CAS 838897-85-1
3-(3-Methoxyphenyl)-5-(2-phenylethyl)-1,2,4-oxadiazole
CAS 838897-85-1C17H16N2O2
2-Phenyl-1-(3-phenyl-1,2,4-oxadiazol-5-yl)ethanamine chemical structure, C16H15N3O, CAS 790270-69-8
2-Phenyl-1-(3-phenyl-1,2,4-oxadiazol-5-yl)ethanamine
CAS 790270-69-8C16H15N3O
1-[3-(4-Chlorophenyl)-1,2,4-oxadiazol-5-yl]-2-phenylethan-1-amine chemical structure, C16H14ClN3O, CAS 929975-49-5
1-[3-(4-Chlorophenyl)-1,2,4-oxadiazol-5-yl]-2-phenylethan-1-amine
CAS 929975-49-5C16H14ClN3O
1-Phenyl-2-(3-phenyl-1,2,4-oxadiazol-5-yl)ethanamine chemical structure, C16H15N3O, CAS 1036605-83-0
1-Phenyl-2-(3-phenyl-1,2,4-oxadiazol-5-yl)ethanamine
CAS 1036605-83-0C16H15N3O
1-[3-(4-Chlorophenyl)-1,2,4-oxadiazol-5-yl]-2-phenylethan-1-amine, oxalic acid chemical structure, C18H16ClN3O5, CAS 1259130-85-2
1-[3-(4-Chlorophenyl)-1,2,4-oxadiazol-5-yl]-2-phenylethan-1-amine, oxalic acid
CAS 1259130-85-2C18H16ClN3O5
2-Phenyl-1-(3-phenyl-1,2,4-oxadiazol-5-yl)ethan-1-amine oxalate chemical structure, C18H17N3O5, CAS 2126176-74-5
2-Phenyl-1-(3-phenyl-1,2,4-oxadiazol-5-yl)ethan-1-amine oxalate
CAS 2126176-74-5C18H17N3O5