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Murcko scaffold

Ring system with 3 rings and 18 atoms

10 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
10
With full pages
3
Scaffold SMILES

c1ccc(Cn2ccc(-c3cccnc3)n2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Cn2ccc(-c3cccnc3)n2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

1-Benzyl-3-(pyridin-3-yl)-1H-pyrazole-4-carbaldehyde chemical structure, C16H13N3O, CAS 956504-56-6
1-Benzyl-3-(pyridin-3-yl)-1H-pyrazole-4-carbaldehyde
CAS 956504-56-6C16H13N3O
1-Benzyl-3-(pyridin-3-yl)-1H-pyrazole-4-carboxylic acid chemical structure, C16H13N3O2, CAS 956959-59-4
1-Benzyl-3-(pyridin-3-yl)-1H-pyrazole-4-carboxylic acid
CAS 956959-59-4C16H13N3O2
3-[1-Benzyl-3-(pyridin-3-yl)-1H-pyrazol-4-yl]prop-2-enoic acid chemical structure, C18H15N3O2, CAS 956244-24-9
3-[1-Benzyl-3-(pyridin-3-yl)-1H-pyrazol-4-yl]prop-2-enoic acid
CAS 956244-24-9C18H15N3O2
(E)-3-(1-Benzyl-3-pyridin-3-ylpyrazol-4-yl)-2-cyano-N-propan-2-ylprop-2-enamide chemical structure, C22H21N5O
(E)-3-(1-Benzyl-3-pyridin-3-ylpyrazol-4-yl)-2-cyano-N-propan-2-ylprop-2-enamide
C22H21N5O
1-Benzyl-N-(2-methylpropyl)-3-(pyridin-3-yl)-1H-pyrazole-4-carboxamide chemical structure, C20H22N4O, CAS 956440-16-7
1-Benzyl-N-(2-methylpropyl)-3-(pyridin-3-yl)-1H-pyrazole-4-carboxamide
CAS 956440-16-7C20H22N4O
2-Benzyl-5-pyridin-3-ylpyrazol-3-amine chemical structure, C15H14N4, CAS 93734-29-3
2-Benzyl-5-pyridin-3-ylpyrazol-3-amine
CAS 93734-29-3C15H14N4
3-[1-Benzyl-3-(pyridin-3-yl)-1H-pyrazol-4-yl]-2-cyano-N-(2-methoxyethyl)prop-2-enamide chemical structure, C22H21N5O2, CAS 1007191-35-6
3-[1-Benzyl-3-(pyridin-3-yl)-1H-pyrazol-4-yl]-2-cyano-N-(2-methoxyethyl)prop-2-enamide
CAS 1007191-35-6C22H21N5O2
3-[1-Benzyl-3-(pyridin-3-yl)-1H-pyrazol-4-yl]-2-cyano-N-(propan-2-yl)prop-2-enamide chemical structure, C22H21N5O
3-[1-Benzyl-3-(pyridin-3-yl)-1H-pyrazol-4-yl]-2-cyano-N-(propan-2-yl)prop-2-enamide
C22H21N5O
(Z)-3-(1-Benzyl-3-pyridin-3-ylpyrazol-4-yl)-2-cyanoprop-2-enamide chemical structure, C19H15N5O, CAS 1147375-72-1
(Z)-3-(1-Benzyl-3-pyridin-3-ylpyrazol-4-yl)-2-cyanoprop-2-enamide
CAS 1147375-72-1C19H15N5O
(Z)-3-(1-Benzyl-3-pyridin-3-ylpyrazol-4-yl)-2-cyano-N-propan-2-ylprop-2-enamide chemical structure, C22H21N5O, CAS 1147355-77-8
(Z)-3-(1-Benzyl-3-pyridin-3-ylpyrazol-4-yl)-2-cyano-N-propan-2-ylprop-2-enamide
CAS 1147355-77-8C22H21N5O