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Murcko scaffold

Ring system with 3 rings and 19 atoms

16 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
16
With full pages
5
Scaffold SMILES

c1ccc(NCc2nnc(-c3ccccc3)o2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(NCc2nnc(-c3ccccc3)o2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

2-Ethoxy-N-[(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]aniline chemical structure, C17H17N3O2, CAS 853750-08-0
2-Ethoxy-N-[(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]aniline
CAS 853750-08-0C17H17N3O2
5-Chloro-2-methoxy-N-[(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]aniline chemical structure, C16H14ClN3O2, CAS 853750-19-3
5-Chloro-2-methoxy-N-[(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]aniline
CAS 853750-19-3C16H14ClN3O2
2,3-Dimethyl-N-[(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]aniline chemical structure, C17H17N3O, CAS 853750-12-6
2,3-Dimethyl-N-[(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]aniline
CAS 853750-12-6C17H17N3O
2-Methoxy-N-[(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]aniline chemical structure, C16H15N3O2, CAS 853750-06-8
2-Methoxy-N-[(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]aniline
CAS 853750-06-8C16H15N3O2
4-Methoxy-N-[(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]aniline chemical structure, C16H15N3O2, CAS 50939-80-5
4-Methoxy-N-[(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]aniline
CAS 50939-80-5C16H15N3O2
4-Ethoxy-N-[(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]aniline chemical structure, C17H17N3O2, CAS 162694-06-6
4-Ethoxy-N-[(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]aniline
CAS 162694-06-6C17H17N3O2
4-Bromo-N-[(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]aniline chemical structure, C15H12BrN3O, CAS 162694-04-4
4-Bromo-N-[(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]aniline
CAS 162694-04-4C15H12BrN3O
N-[(5-Phenyl-1,3,4-oxadiazol-2-yl)methyl]-4-(trifluoromethoxy)aniline chemical structure, C16H12F3N3O2, CAS 881989-32-8
N-[(5-Phenyl-1,3,4-oxadiazol-2-yl)methyl]-4-(trifluoromethoxy)aniline
CAS 881989-32-8C16H12F3N3O2
3-Fluoro-4-methyl-N-[(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]aniline chemical structure, C16H14FN3O, CAS 881990-07-4
3-Fluoro-4-methyl-N-[(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]aniline
CAS 881990-07-4C16H14FN3O
5-(2-Bromophenyl)-N-(4-iodophenyl)-1,3,4-oxadiazole-2-methanamine chemical structure, C15H11BrIN3O, CAS 1097789-95-1
5-(2-Bromophenyl)-N-(4-iodophenyl)-1,3,4-oxadiazole-2-methanamine
CAS 1097789-95-1C15H11BrIN3O
2-Chloro-4-(((1R,2S)-1-(5-(4-cyanophenyl)-1,3,4-oxadiazol-2-yl)-2-hydroxypropyl)amino)-3-methylbenzonitrile chemical structure, C20H16ClN5O2, CAS 1182367-47-0
2-Chloro-4-(((1R,2S)-1-(5-(4-cyanophenyl)-1,3,4-oxadiazol-2-yl)-2-hydroxypropyl)amino)-3-methylbenzonitrile
CAS 1182367-47-0C20H16ClN5O2
2-Chloro-4-((1R,2R)-1-(5-(4-cyanophenyl)-1,3,4-oxadiazol-2-yl)-2-hydroxypropylamino)-3-methylbenzonitrile chemical structure, C20H16ClN5O2, CAS 1182367-51-6
2-Chloro-4-((1R,2R)-1-(5-(4-cyanophenyl)-1,3,4-oxadiazol-2-yl)-2-hydroxypropylamino)-3-methylbenzonitrile
CAS 1182367-51-6C20H16ClN5O2
4-(5-{[Cyano(3-ethylphenyl)amino]methyl}-1,3,4-oxadiazol-2-yl)benzonitrile chemical structure, C19H15N5O, CAS 1424580-65-3
4-(5-{[Cyano(3-ethylphenyl)amino]methyl}-1,3,4-oxadiazol-2-yl)benzonitrile
CAS 1424580-65-3C19H15N5O
N-Cyano-3-ethyl-N-{[5-(2-methoxyphenyl)-1,3,4-oxadiazol-2-yl]methyl}aniline chemical structure, C19H18N4O2, CAS 1424495-48-6
N-Cyano-3-ethyl-N-{[5-(2-methoxyphenyl)-1,3,4-oxadiazol-2-yl]methyl}aniline
CAS 1424495-48-6C19H18N4O2
N-Cyano-3-ethyl-N-{[5-(3-fluorophenyl)-1,3,4-oxadiazol-2-yl]methyl}aniline chemical structure, C18H15FN4O, CAS 1444588-88-8
N-Cyano-3-ethyl-N-{[5-(3-fluorophenyl)-1,3,4-oxadiazol-2-yl]methyl}aniline
CAS 1444588-88-8C18H15FN4O
N-{[5-(3-Bromophenyl)-1,3,4-oxadiazol-2-yl]methyl}-N-cyano-3-ethylaniline chemical structure, C18H15BrN4O, CAS 1808848-53-4
N-{[5-(3-Bromophenyl)-1,3,4-oxadiazol-2-yl]methyl}-N-cyano-3-ethylaniline
CAS 1808848-53-4C18H15BrN4O