CompoundList
Sign in
Murcko scaffold

1-[(5-Phenylthiophen-2-yl)methyl]piperazine scaffold

13 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
13
With full pages
5
Scaffold SMILES

c1ccc(-c2ccc(CN3CCNCC3)s2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-[(5-Phenylthiophen-2-yl)methyl]piperazine page
Murcko scaffold c1ccc(-c2ccc(CN3CCNCC3)s2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

1-{[5-(2-Fluorophenyl)thiophen-2-yl]methyl}piperazine chemical structure, C15H17FN2S, CAS 1000932-42-2
1-{[5-(2-Fluorophenyl)thiophen-2-yl]methyl}piperazine
CAS 1000932-42-2C15H17FN2S
1-{[5-(2-Chlorophenyl)thiophen-2-yl]methyl}piperazine chemical structure, C15H17ClN2S, CAS 1000932-50-2
1-{[5-(2-Chlorophenyl)thiophen-2-yl]methyl}piperazine
CAS 1000932-50-2C15H17ClN2S
1-{[5-(4-Chlorophenyl)thiophen-2-yl]methyl}piperazine chemical structure, C15H17ClN2S, CAS 1171815-46-5
1-{[5-(4-Chlorophenyl)thiophen-2-yl]methyl}piperazine
CAS 1171815-46-5C15H17ClN2S
1-((5-(2-Nitrophenyl)thiophen-2-yl)methyl)piperazine chemical structure, C15H17N3O2S, CAS 1050910-03-6
1-((5-(2-Nitrophenyl)thiophen-2-yl)methyl)piperazine
CAS 1050910-03-6C15H17N3O2S
1-{[5-(3-Chlorophenyl)thiophen-2-yl]methyl}piperazine chemical structure, C15H17ClN2S, CAS 1049872-82-3
1-{[5-(3-Chlorophenyl)thiophen-2-yl]methyl}piperazine
CAS 1049872-82-3C15H17ClN2S
1-((5-(3-Fluorophenyl)thiophen-2-yl)methyl)piperazine chemical structure, C15H17FN2S, CAS 1049872-87-8
1-((5-(3-Fluorophenyl)thiophen-2-yl)methyl)piperazine
CAS 1049872-87-8C15H17FN2S
1-{[5-(3-Bromophenyl)thiophen-2-yl]methyl}piperazine chemical structure, C15H17BrN2S, CAS 1087792-11-7
1-{[5-(3-Bromophenyl)thiophen-2-yl]methyl}piperazine
CAS 1087792-11-7C15H17BrN2S
1-{[5-(3-Fluorophenyl)thiophen-2-yl]methyl}-4-(prop-2-yn-1-yl)piperazine chemical structure, C18H19FN2S, CAS 1147676-44-5
1-{[5-(3-Fluorophenyl)thiophen-2-yl]methyl}-4-(prop-2-yn-1-yl)piperazine
CAS 1147676-44-5C18H19FN2S
1-[(5-Phenylthiophen-2-yl)methyl]piperazine chemical structure, C15H18N2S, CAS 1000933-43-6
1-[(5-Phenylthiophen-2-yl)methyl]piperazine
CAS 1000933-43-6C15H18N2S
1-{[5-(4-Chlorophenyl)thien-2-yl]methyl}piperazine dihydrochloride chemical structure, C15H19Cl3N2S, CAS 1171715-58-4
1-{[5-(4-Chlorophenyl)thien-2-yl]methyl}piperazine dihydrochloride
CAS 1171715-58-4C15H19Cl3N2S
1-{[5-(4-Bromophenyl)thiophen-2-yl]methyl}piperazine chemical structure, C15H17BrN2S, CAS 1050909-79-9
1-{[5-(4-Bromophenyl)thiophen-2-yl]methyl}piperazine
CAS 1050909-79-9C15H17BrN2S
tert-Butyl 4-{[5-(4-bromophenyl)thiophen-2-yl]methyl}piperazine-1-carboxylate chemical structure, C20H25BrN2O2S, CAS 2680668-28-2
tert-Butyl 4-{[5-(4-bromophenyl)thiophen-2-yl]methyl}piperazine-1-carboxylate
CAS 2680668-28-2C20H25BrN2O2S
tert-Butyl 4-{[5-(3-bromophenyl)thiophen-2-yl]methyl}piperazine-1-carboxylate chemical structure, C20H25BrN2O2S, CAS 2680899-31-2
tert-Butyl 4-{[5-(3-bromophenyl)thiophen-2-yl]methyl}piperazine-1-carboxylate
CAS 2680899-31-2C20H25BrN2O2S