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Murcko scaffold

2-Benzylthiobenzimidazole scaffold

124 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
124
With full pages
34
Scaffold SMILES

c1ccc(CSc2nc3ccccc3[nH]2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Benzylthiobenzimidazole page
Murcko scaffold c1ccc(CSc2nc3ccccc3[nH]2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 96 of 124 chemicals

2-[(4-Propan-2-ylphenyl)methylsulfanyl]-1H-benzimidazole chemical structure, C17H18N2S, CAS 537010-50-7
2-[(4-Propan-2-ylphenyl)methylsulfanyl]-1H-benzimidazole
CAS 537010-50-7C17H18N2S
2-[(2-Chloro-6-nitrobenzyl)sulfanyl]-1H-benzimidazole chemical structure, C14H10ClN3O2S, CAS 693229-79-7
2-[(2-Chloro-6-nitrobenzyl)sulfanyl]-1H-benzimidazole
CAS 693229-79-7C14H10ClN3O2S
2-[(2,4,6-Trimethylbenzyl)sulfanyl]-1H-benzimidazole chemical structure, C17H18N2S, CAS 693241-73-5
2-[(2,4,6-Trimethylbenzyl)sulfanyl]-1H-benzimidazole
CAS 693241-73-5C17H18N2S
2-[(2,5-Dimethylphenyl)methylsulfanyl]-1H-benzimidazole chemical structure, C16H16N2S, CAS 615280-11-0
2-[(2,5-Dimethylphenyl)methylsulfanyl]-1H-benzimidazole
CAS 615280-11-0C16H16N2S
5-Methyl-2-((2-methylbenzyl)thio)-1H-benzo[d]imidazole chemical structure, C16H16N2S, CAS 637323-00-3
5-Methyl-2-((2-methylbenzyl)thio)-1H-benzo[d]imidazole
CAS 637323-00-3C16H16N2S
3-[(1H-Benzimidazol-2-ylthio)methyl]-4-methoxybenzaldehyde chemical structure, C16H14N2O2S, CAS 615280-10-9
3-[(1H-Benzimidazol-2-ylthio)methyl]-4-methoxybenzaldehyde
CAS 615280-10-9C16H14N2O2S
2-[(4-Bromo-2,3,5,6-tetramethylbenzyl)sulfanyl]-1H-benzimidazole chemical structure, C18H19BrN2S, CAS 306746-16-7
2-[(4-Bromo-2,3,5,6-tetramethylbenzyl)sulfanyl]-1H-benzimidazole
CAS 306746-16-7C18H19BrN2S
2-[(3-Iodophenyl)methylsulfanyl]-1H-benzimidazole chemical structure, C14H11IN2S, CAS 425651-03-2
2-[(3-Iodophenyl)methylsulfanyl]-1H-benzimidazole
CAS 425651-03-2C14H11IN2S
2-{[(2-Fluorophenyl)methyl]sulfanyl}-1H-1,3-benzodiazole chemical structure, C14H11FN2S, CAS 475977-75-4
2-{[(2-Fluorophenyl)methyl]sulfanyl}-1H-1,3-benzodiazole
CAS 475977-75-4C14H11FN2S
4-(((1H-Benzo[d]imidazol-2-yl)thio)methyl)-N-(3-hydroxypropyl)benzamide chemical structure, C18H19N3O2S, CAS 308298-96-6
4-(((1H-Benzo[d]imidazol-2-yl)thio)methyl)-N-(3-hydroxypropyl)benzamide
CAS 308298-96-6C18H19N3O2S
2-[(4-Propoxybenzyl)thio]-1H-benzimidazole chemical structure, C17H18N2OS, CAS 537702-10-6
2-[(4-Propoxybenzyl)thio]-1H-benzimidazole
CAS 537702-10-6C17H18N2OS
2-[(3-Methoxyphenyl)methylsulfanyl]-1H-benzimidazole chemical structure, C15H14N2OS, CAS 475977-76-5
2-[(3-Methoxyphenyl)methylsulfanyl]-1H-benzimidazole
CAS 475977-76-5C15H14N2OS
4-[(1H-1,3-Benzodiazol-2-ylsulfanyl)methyl]benzohydrazide chemical structure, C15H14N4OS, CAS 379254-35-0
4-[(1H-1,3-Benzodiazol-2-ylsulfanyl)methyl]benzohydrazide
CAS 379254-35-0C15H14N4OS
2-[(1H-1,3-Benzodiazol-2-ylsulfanyl)methyl]benzoic acid chemical structure, C15H12N2O2S, CAS 733795-48-7
2-[(1H-1,3-Benzodiazol-2-ylsulfanyl)methyl]benzoic acid
CAS 733795-48-7C15H12N2O2S
4-(1H-Benzimidazol-2-ylsulfanylmethyl)benzonitrile chemical structure, C15H11N3S, CAS 475977-83-4
4-(1H-Benzimidazol-2-ylsulfanylmethyl)benzonitrile
CAS 475977-83-4C15H11N3S
2-(2-Methyl-5-nitrobenzylthio)-1H-benzo[d]imidazole chemical structure, C15H13N3O2S, CAS 845879-34-7
2-(2-Methyl-5-nitrobenzylthio)-1H-benzo[d]imidazole
CAS 845879-34-7C15H13N3O2S
Methyl 2-(2-methyl-5-nitrobenzylthio)-1H-benzo[d]imidazole-1-carboxylate chemical structure, C17H15N3O4S, CAS 845879-35-8
Methyl 2-(2-methyl-5-nitrobenzylthio)-1H-benzo[d]imidazole-1-carboxylate
CAS 845879-35-8C17H15N3O4S
2-(2,4-Dinitrobenzylthio)-1H-benzo[d]imidazole chemical structure, C14H10N4O4S, CAS 475977-79-8
2-(2,4-Dinitrobenzylthio)-1H-benzo[d]imidazole
CAS 475977-79-8C14H10N4O4S
Ethyl 2-((2-methyl-5-nitrobenzyl)thio)-1H-benzo[d]imidazole-1-carboxylate chemical structure, C18H17N3O4S, CAS 845879-36-9
Ethyl 2-((2-methyl-5-nitrobenzyl)thio)-1H-benzo[d]imidazole-1-carboxylate
CAS 845879-36-9C18H17N3O4S
N-{1-[2-(Benzylsulfanyl)-1H-benzimidazol-1-yl]-2,2,2-trichloroethyl}acetamide chemical structure, C18H16Cl3N3OS, CAS 374095-28-0
N-{1-[2-(Benzylsulfanyl)-1H-benzimidazol-1-yl]-2,2,2-trichloroethyl}acetamide
CAS 374095-28-0C18H16Cl3N3OS
2-((1-Phenylethyl)thio)-1H-benzo[d]imidazole chemical structure, C15H14N2S, CAS 333746-89-7
2-((1-Phenylethyl)thio)-1H-benzo[d]imidazole
CAS 333746-89-7C15H14N2S
1-[3-[(5,6-Dimethyl-1H-benzimidazol-2-yl)sulfanylmethyl]-4-methoxyphenyl]ethanone chemical structure, C19H20N2O2S, CAS 694447-86-4
1-[3-[(5,6-Dimethyl-1H-benzimidazol-2-yl)sulfanylmethyl]-4-methoxyphenyl]ethanone
CAS 694447-86-4C19H20N2O2S
1-[2-[(4-Fluorophenyl)methylsulfanyl]benzimidazol-1-yl]ethanone chemical structure, C16H13FN2OS, CAS 838898-39-8
1-[2-[(4-Fluorophenyl)methylsulfanyl]benzimidazol-1-yl]ethanone
CAS 838898-39-8C16H13FN2OS
2-((Phenylmethyl)thio)-1H-benzimidazol-1-amine chemical structure, C14H13N3S, CAS 151693-53-7
2-((Phenylmethyl)thio)-1H-benzimidazol-1-amine
CAS 151693-53-7C14H13N3S