Murcko scaffold
N-Benzyloxyphthalimide scaffold
52 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 19
- Chemicals
- 52
- With full pages
- 7
Scaffold SMILES
O=C1c2ccccc2C(=O)N1OCc1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 52 chemicals
Phthalimide, N-(m-nitrobenzyloxy)-
CAS 30777-84-5C15H10N2O5
N-Benzyloxyphthalimide
CAS 16653-19-3C15H11NO3
![2-[(2-Nitrobenzyl)oxy]-1H-isoindole-1,3(2H)-dione chemical structure, C15H10N2O5, CAS 30777-83-4](/s/UCMHYRMMWUXXTF-UHFFFAOYSA-N.svg)
2-[(2-Nitrobenzyl)oxy]-1H-isoindole-1,3(2H)-dione
CAS 30777-83-4C15H10N2O5
N-(3-Trifluoromethylbenzyloxy)phthalimide
CAS 30777-88-9C16H10F3NO3
2-((4-Methoxybenzyl)oxy)isoindoline-1,3-dione
CAS 2014-61-1C16H13NO4
![2-[(2-Chlorobenzyl)oxy]-1H-isoindole-1,3(2H)-dione chemical structure, C15H10ClNO3, CAS 38936-63-9](/s/GIRZROTWZXVXPX-UHFFFAOYSA-N.svg)
2-[(2-Chlorobenzyl)oxy]-1H-isoindole-1,3(2H)-dione
CAS 38936-63-9C15H10ClNO3
![2-[(3-Chloro-4-propan-2-yloxyphenyl)methoxy]isoindole-1,3-dione chemical structure, C18H16ClNO4, CAS 97267-89-5](/s/AQPWBKQAYGRJJT-UHFFFAOYSA-N.svg)
2-[(3-Chloro-4-propan-2-yloxyphenyl)methoxy]isoindole-1,3-dione
CAS 97267-89-5C18H16ClNO4
![2-[(3-Chloro-4-ethoxyphenyl)methoxy]isoindole-1,3-dione chemical structure, C17H14ClNO4, CAS 97268-32-1](/s/MQRPEBYBMNQSFL-UHFFFAOYSA-N.svg)
2-[(3-Chloro-4-ethoxyphenyl)methoxy]isoindole-1,3-dione
CAS 97268-32-1C17H14ClNO4
![2-[(5-Bromo-2-methoxyphenyl)methoxy]isoindole-1,3-dione chemical structure, C16H12BrNO4, CAS 23993-39-7](/s/OMTPBFVJSICCNE-UHFFFAOYSA-N.svg)
2-[(5-Bromo-2-methoxyphenyl)methoxy]isoindole-1,3-dione
CAS 23993-39-7C16H12BrNO4
![2-[(4-Fluorobenzyl)oxy]-1H-isoindole-1,3(2H)-dione chemical structure, C15H10FNO3, CAS 76866-37-0](/s/MYQPSWQVVSNZAK-UHFFFAOYSA-N.svg)
2-[(4-Fluorobenzyl)oxy]-1H-isoindole-1,3(2H)-dione
CAS 76866-37-0C15H10FNO3
![2-[(4-Chlorobenzyl)oxy]-1H-isoindole-1,3(2H)-dione chemical structure, C15H10ClNO3, CAS 39030-46-1](/s/DWVJTIVMISRPNK-UHFFFAOYSA-N.svg)
2-[(4-Chlorobenzyl)oxy]-1H-isoindole-1,3(2H)-dione
CAS 39030-46-1C15H10ClNO3
2-((3-Methoxybenzyl)oxy)isoindoline-1,3-dione
CAS 2014-60-0C16H13NO4
![2-[(2-Fluorobenzyl)oxy]-1H-isoindole-1,3(2H)-dione chemical structure, C15H10FNO3, CAS 55418-28-5](/s/YMQYWCYSGSJTHC-UHFFFAOYSA-N.svg)
2-[(2-Fluorobenzyl)oxy]-1H-isoindole-1,3(2H)-dione
CAS 55418-28-5C15H10FNO3
![2-[(3-Fluorobenzyl)oxy]-1H-isoindole-1,3(2H)-dione chemical structure, C15H10FNO3, CAS 30777-87-8](/s/OHJQMVAYLOZKBF-UHFFFAOYSA-N.svg)
2-[(3-Fluorobenzyl)oxy]-1H-isoindole-1,3(2H)-dione
CAS 30777-87-8C15H10FNO3
![2-[(2,6-Dichlorophenyl)methoxy]isoindole-1,3-dione chemical structure, C15H9Cl2NO3, CAS 2025-43-6](/s/QVMAVYVJYYXZTI-UHFFFAOYSA-N.svg)
2-[(2,6-Dichlorophenyl)methoxy]isoindole-1,3-dione
CAS 2025-43-6C15H9Cl2NO3
![2-[(3-Chlorophenyl)methoxy]isoindole-1,3-dione chemical structure, C15H10ClNO3, CAS 30777-86-7](/s/MESQAGATDOBCOC-UHFFFAOYSA-N.svg)
2-[(3-Chlorophenyl)methoxy]isoindole-1,3-dione
CAS 30777-86-7C15H10ClNO3
![2-[(3,5-Dichlorophenyl)methoxy]isoindole-1,3-dione chemical structure, C15H9Cl2NO3, CAS 251310-34-6](/s/WEUQHXWTJZCVPQ-UHFFFAOYSA-N.svg)
2-[(3,5-Dichlorophenyl)methoxy]isoindole-1,3-dione
CAS 251310-34-6C15H9Cl2NO3
![2-[(2-Chloro-4-fluorophenyl)methoxy]isoindole-1,3-dione chemical structure, C15H9ClFNO3, CAS 321430-34-6](/s/JCCMOFWUTOIBPU-UHFFFAOYSA-N.svg)
2-[(2-Chloro-4-fluorophenyl)methoxy]isoindole-1,3-dione
CAS 321430-34-6C15H9ClFNO3
![2-[(2,5-Dichlorophenyl)methoxy]isoindole-1,3-dione chemical structure, C15H9Cl2NO3, CAS 321430-35-7](/s/OCHLPMIDBOBYBN-UHFFFAOYSA-N.svg)
2-[(2,5-Dichlorophenyl)methoxy]isoindole-1,3-dione
CAS 321430-35-7C15H9Cl2NO3
![2-[(2,3-Dichlorophenyl)methoxy]isoindole-1,3-dione chemical structure, C15H9Cl2NO3, CAS 321430-36-8](/s/CZKHASYPHVMQIJ-UHFFFAOYSA-N.svg)
2-[(2,3-Dichlorophenyl)methoxy]isoindole-1,3-dione
CAS 321430-36-8C15H9Cl2NO3
2-((2-(Trifluoromethyl)benzyl)oxy)isoindoline-1,3-dione
CAS 321430-37-9C16H10F3NO3
![2-[(2-Methoxyphenyl)methoxy]isoindole-1,3-dione chemical structure, C16H13NO4, CAS 321430-43-7](/s/UETLTMCWLRSRJK-UHFFFAOYSA-N.svg)
2-[(2-Methoxyphenyl)methoxy]isoindole-1,3-dione
CAS 321430-43-7C16H13NO4
![2-[(3-Chloro-2-fluorophenyl)methoxy]isoindole-1,3-dione chemical structure, C15H9ClFNO3, CAS 321430-44-8](/s/LHPLAVSEMFIJOR-UHFFFAOYSA-N.svg)
2-[(3-Chloro-2-fluorophenyl)methoxy]isoindole-1,3-dione
CAS 321430-44-8C15H9ClFNO3
![2-[[4-(Trifluoromethyl)phenyl]methoxy]isoindole-1,3-dione chemical structure, C16H10F3NO3, CAS 339096-92-3](/s/WZPRPDFZIQXXOR-UHFFFAOYSA-N.svg)
2-[[4-(Trifluoromethyl)phenyl]methoxy]isoindole-1,3-dione
CAS 339096-92-3C16H10F3NO3
- 2-((4-Methylbenzyl)oxy)isoindoline-1,3-dione38936-61-7C16H13NO3
- 2-[(2-Chloro-6-fluorophenyl)methoxy]isoindole-1,3-dione303997-16-2C15H9ClFNO3
- 2-((3,4-Dichlorobenzyl)oxy)isoindoline-1,3-dione38936-82-2C15H9Cl2NO3
- 2-[(2-Bromobenzyl)oxy]-1H-isoindole-1,3(2H)-dione321430-33-5C15H10BrNO3
- Methyl 4-{[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)oxy]methyl}benzenecarboxylate339011-73-3C17H13NO5
- 2-[(4-Nitrobenzyl)oxy]-1H-isoindole-1,3(2H)-dione30777-85-6C15H10N2O5
- 2-[(2,4-Dichlorobenzyl)oxy]-1H-isoindole-1,3(2H)-dione339106-00-2C15H9Cl2NO3
- 2-[(3-Bromophenyl)methoxy]isoindole-1,3-dione137107-28-9C15H10BrNO3
- Methyl 3-[[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)oxy]methyl]-4-hydroxybenzoate38573-38-5C17H13NO6
- 2-[(Perfluorophenyl)methoxy]isoindoline-1,3-dione57981-01-8C15H6F5NO3
- 4-(((1,3-Dioxoisoindolin-2-yl)oxy)methyl)-3-nitrobenzene-1-sulfonyl chloride130129-52-1C15H9ClN2O7S
- (E)-Methyl 2-[phthalimidooxymethylphenyl]-3-methoxypropenoate145948-09-0C20H17NO6
- Methyl 2-(2-(((1,3-dioxoisoindolin-2-yl)oxy)methyl)phenyl)-2-(methoxyimino)acetate139752-38-8C19H16N2O6
- (E)-Methyl 2-(2-(((1,3-dioxoisoindolin-2-yl)oxy)methyl)phenyl)-2-(methoxyimino)acetate156581-14-5C19H16N2O6
- 2-((2,4-Dimethoxybenzyl)oxy)isoindoline-1,3-dione216067-79-7C17H15NO5
- 2-(1-Phenylethoxy)isoindoline-1,3-dione172789-09-2C16H13NO3
- 2-[(4-Bromophenyl)methoxy]-1H-isoindole-1,3(2H)-dione55418-33-2C15H10BrNO3
- 4-{[(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)oxy]methyl}benzonitrile2086-27-3C16H10N2O3
- 2-[[4-[(2-Methylpropan-2-yl)oxy]phenyl]methoxy]isoindole-1,3-dione1091612-64-4C19H19NO4
- 2-{[4-(Methylsulfonyl)benzyl]oxy}-1H-isoindole-1,3(2H)-dione1091611-37-8C16H13NO5S
- N-(4-Isopropylbenzyloxy)phthalimide796061-04-6C18H17NO3
- 2-[(3,4-Dimethylphenyl)methoxy]-1H-isoindole-1,3(2H)-dione113201-27-7C17H15NO3
- 2-((2-Methylbenzyl)oxy)isoindoline-1,3-dione681160-67-8C16H13NO3
- 2-((3-Methylbenzyl)oxy)isoindoline-1,3-dione602314-41-0C16H13NO3
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(Nc1nc2ccccc2s1)c1ccccc1122 chemicals
O=C(Nc1ccccc1)c1cc2ccccc2o164 chemicals
O=C(Nc1cc2c(s1)CCCC2)c1ccccc160 chemicals![Scaffold O=S(Cc1ccccn1)c1nc2ccccc2[nH]1](/scaffold/HBDKFZNDMVLSHM-UHFFFAOYSA-N/structure.svg)
O=S(Cc1ccccn1)c1nc2ccccc2[nH]154 chemicals![Scaffold C(=Cc1nc2ccccc2[nH]1)c1ccccc1](/scaffold/QQLPPRIZUPEKMV-UHFFFAOYSA-N/structure.svg)
C(=Cc1nc2ccccc2[nH]1)c1ccccc149 chemicals![Scaffold c1ccc(OCc2nc3ccccc3[nH]2)cc1](/scaffold/XATKRQREMKIRLA-UHFFFAOYSA-N/structure.svg)
c1ccc(OCc2nc3ccccc3[nH]2)cc147 chemicals![Scaffold O=c1[nH]c(=O)c2nc(SCc3ccccc3)[nH]c2[nH]1](/scaffold/DPACPINNZAEEGT-UHFFFAOYSA-N/structure.svg)
O=c1[nH]c(=O)c2nc(SCc3ccccc3)[nH]c2[nH]138 chemicals![Scaffold O=C(Nc1nc2ccccc2[nH]1)c1ccccc1](/scaffold/LYLQJTSHZYGWBO-UHFFFAOYSA-N/structure.svg)
O=C(Nc1nc2ccccc2[nH]1)c1ccccc137 chemicals![Scaffold c1ccc(CSc2nc3ccccc3[nH]2)cc1](/scaffold/IJINDUSMSVDESS-UHFFFAOYSA-N/structure.svg)
c1ccc(CSc2nc3ccccc3[nH]2)cc134 chemicals![Scaffold O=c1[nH]c(=O)c2[nH]c(NCc3ccccc3)nc2[nH]1](/scaffold/GWEJMPIBANKNEQ-UHFFFAOYSA-N/structure.svg)
O=c1[nH]c(=O)c2[nH]c(NCc3ccccc3)nc2[nH]132 chemicals
O=C(Nc1ccccc1)c1cc2ccccc2s130 chemicals![Scaffold c1ccc(CNc2nc3ccccc3[nH]2)cc1](/scaffold/FXMPPQGQNSTUGE-UHFFFAOYSA-N/structure.svg)
c1ccc(CNc2nc3ccccc3[nH]2)cc128 chemicals