CompoundList
Sign in
Murcko scaffold

Ring system with 2 rings and 19 atoms

55 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
19
Chemicals
55
With full pages
9
Scaffold SMILES

O=C(COC(=O)c1cccs1)NCc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(COC(=O)c1cccs1)NCc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 55 of 55 chemicals

{[(3-Methylphenyl)methyl]carbamoyl}methyl 5-methylthiophene-2-carboxylate chemical structure, C16H17NO3S, CAS 1794983-79-1
{[(3-Methylphenyl)methyl]carbamoyl}methyl 5-methylthiophene-2-carboxylate
CAS 1794983-79-1C16H17NO3S
({[2-(Trifluoromethyl)phenyl]methyl}carbamoyl)methyl 3-methylthiophene-2-carboxylate chemical structure, C16H14F3NO3S, CAS 1794897-36-1
({[2-(Trifluoromethyl)phenyl]methyl}carbamoyl)methyl 3-methylthiophene-2-carboxylate
CAS 1794897-36-1C16H14F3NO3S
{[(4-Bromophenyl)methyl]carbamoyl}methyl 3-methylthiophene-2-carboxylate chemical structure, C15H14BrNO3S, CAS 1794916-32-7
{[(4-Bromophenyl)methyl]carbamoyl}methyl 3-methylthiophene-2-carboxylate
CAS 1794916-32-7C15H14BrNO3S
2-((3-Bromobenzyl)amino)-2-oxoethyl thiophene-2-carboxylate chemical structure, C14H12BrNO3S, CAS 1794896-59-5
2-((3-Bromobenzyl)amino)-2-oxoethyl thiophene-2-carboxylate
CAS 1794896-59-5C14H12BrNO3S
{[(2,4-Difluorophenyl)methyl]carbamoyl}methyl thiophene-2-carboxylate chemical structure, C14H11F2NO3S, CAS 1794741-57-3
{[(2,4-Difluorophenyl)methyl]carbamoyl}methyl thiophene-2-carboxylate
CAS 1794741-57-3C14H11F2NO3S
{[1-(4-Methylphenyl)ethyl]carbamoyl}methyl thiophene-2-carboxylate chemical structure, C16H17NO3S, CAS 1794798-50-7
{[1-(4-Methylphenyl)ethyl]carbamoyl}methyl thiophene-2-carboxylate
CAS 1794798-50-7C16H17NO3S
{[(4-Ethylphenyl)methyl]carbamoyl}methyl thiophene-2-carboxylate chemical structure, C16H17NO3S, CAS 1794777-08-4
{[(4-Ethylphenyl)methyl]carbamoyl}methyl thiophene-2-carboxylate
CAS 1794777-08-4C16H17NO3S