CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 18 atoms

14 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
14
With full pages
3
Scaffold SMILES

c1ccc(-c2ccnc(-c3ccccn3)n2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(-c2ccnc(-c3ccccn3)n2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

4-(Diethylamino)-6-phenyl-2-(2-pyridinyl)-5-pyrimidinecarbonitrile chemical structure, C20H19N5, CAS 320418-14-2
4-(Diethylamino)-6-phenyl-2-(2-pyridinyl)-5-pyrimidinecarbonitrile
CAS 320418-14-2C20H19N5
4-(4-Chlorophenyl)-6-(diethylamino)-2-(2-pyridinyl)-5-pyrimidinecarbonitrile chemical structure, C20H18ClN5, CAS 320418-15-3
4-(4-Chlorophenyl)-6-(diethylamino)-2-(2-pyridinyl)-5-pyrimidinecarbonitrile
CAS 320418-15-3C20H18ClN5
4-(Dimethylamino)-6-phenyl-2-(2-pyridinyl)-5-pyrimidinecarbonitrile chemical structure, C18H15N5, CAS 320418-16-4
4-(Dimethylamino)-6-phenyl-2-(2-pyridinyl)-5-pyrimidinecarbonitrile
CAS 320418-16-4C18H15N5
4-(Isopropylamino)-6-phenyl-2-(2-pyridinyl)-5-pyrimidinecarbonitrile chemical structure, C19H17N5, CAS 320418-25-5
4-(Isopropylamino)-6-phenyl-2-(2-pyridinyl)-5-pyrimidinecarbonitrile
CAS 320418-25-5C19H17N5
4-(4-Methoxyphenyl)-6-(methylamino)-2-(2-pyridinyl)-5-pyrimidinecarbonitrile chemical structure, C18H15N5O, CAS 320418-93-7
4-(4-Methoxyphenyl)-6-(methylamino)-2-(2-pyridinyl)-5-pyrimidinecarbonitrile
CAS 320418-93-7C18H15N5O
4-(4-Methoxyphenyl)-5-(methylsulfonyl)-2-(2-pyridinyl)pyrimidine chemical structure, C17H15N3O3S, CAS 400089-28-3
4-(4-Methoxyphenyl)-5-(methylsulfonyl)-2-(2-pyridinyl)pyrimidine
CAS 400089-28-3C17H15N3O3S
4-Chloro-6-(4-chlorophenyl)-2-(2-pyridinyl)-5-pyrimidinecarbonitrile chemical structure, C16H8Cl2N4, CAS 338976-30-0
4-Chloro-6-(4-chlorophenyl)-2-(2-pyridinyl)-5-pyrimidinecarbonitrile
CAS 338976-30-0C16H8Cl2N4
4-(4-Chlorophenyl)-6-(2-propen-1-ylamino)-2-(2-pyridinyl)-5-pyrimidinecarbonitrile chemical structure, C19H14ClN5, CAS 320418-17-5
4-(4-Chlorophenyl)-6-(2-propen-1-ylamino)-2-(2-pyridinyl)-5-pyrimidinecarbonitrile
CAS 320418-17-5C19H14ClN5
4-(2-Methoxyethylamino)-2-pyridin-2-yl-6-[3-(trifluoromethyl)phenyl]pyrimidine-5-carbonitrile chemical structure, C20H16F3N5O, CAS 400080-10-6
4-(2-Methoxyethylamino)-2-pyridin-2-yl-6-[3-(trifluoromethyl)phenyl]pyrimidine-5-carbonitrile
CAS 400080-10-6C20H16F3N5O
3-[[6-(2-Fluorophenyl)-2-pyridin-2-ylpyrimidin-4-yl]amino]propan-1-ol chemical structure, C18H17FN4O, CAS 6485-27-4
3-[[6-(2-Fluorophenyl)-2-pyridin-2-ylpyrimidin-4-yl]amino]propan-1-ol
CAS 6485-27-4C18H17FN4O
2-(6-Methylpyridin-2-yl)-4-phenyl-6-[(prop-2-en-1-yl)oxy]pyrimidine chemical structure, C19H17N3O, CAS 118294-62-5
2-(6-Methylpyridin-2-yl)-4-phenyl-6-[(prop-2-en-1-yl)oxy]pyrimidine
CAS 118294-62-5C19H17N3O
4-Chloro-6-(4-methoxyphenyl)-2-(2-pyridinyl)-5-pyrimidinecarbonitrile chemical structure, C17H11ClN4O, CAS 886361-41-7
4-Chloro-6-(4-methoxyphenyl)-2-(2-pyridinyl)-5-pyrimidinecarbonitrile
CAS 886361-41-7C17H11ClN4O
4-Chloro-6-phenyl-2-(pyridin-2-yl)pyrimidine chemical structure, C15H10ClN3, CAS 10198-67-1
4-Chloro-6-phenyl-2-(pyridin-2-yl)pyrimidine
CAS 10198-67-1C15H10ClN3
2-(5-Chloropyridin-2-yl)-N-methyl-6-phenylpyrimidin-4-amine chemical structure, C16H13ClN4, CAS 1504252-75-8
2-(5-Chloropyridin-2-yl)-N-methyl-6-phenylpyrimidin-4-amine
CAS 1504252-75-8C16H13ClN4