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Murcko scaffold

2-(2-Imino-4-oxo-1,3-thiazolidin-5-yl)-N-phenylacetamide scaffold

71 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 17
Chemicals: 71
With full pages: 16

Scaffold SMILES

N=C1NC(=O)C(CC(=O)Nc2ccccc2)S1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 2-(2-Imino-4-oxo-1,3-thiazolidin-5-yl)-N-phenylacetamide page

Murcko scaffold N=C1NC(=O)C(CC(=O)Nc2ccccc2)S1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 71 chemicals

4-(2-{3-Methyl-2-[(Z)-methylimino]-4-oxo-thiazolidin-5-yl}-acetylamino)-benzoic acid ethyl ester chemical structure, C16H19N3O4S, CAS 1164504-08-8

4-(2-{3-Methyl-2-[(Z)-methylimino]-4-oxo-thiazolidin-5-yl}-acetylamino)-benzoic acid ethyl ester

CAS 1164504-08-8C₁₆H₁₉N₃O₄S

2-[[2-(3-Methyl-2-methylimino-4-oxo-5-thiazolidinyl)-1-oxoethyl]amino]benzoic acid ethyl ester chemical structure, C16H19N3O4S, CAS 1164530-49-7

2-[[2-(3-Methyl-2-methylimino-4-oxo-5-thiazolidinyl)-1-oxoethyl]amino]benzoic acid ethyl ester

CAS 1164530-49-7C₁₆H₁₉N₃O₄S

2-[(2E)-3-Ethyl-2-(ethylimino)-4-oxo-1,3-thiazolidin-5-yl]-N-[3-(trifluoromethyl)phenyl]acetamide chemical structure, C16H18F3N3O2S, CAS 302548-85-2

2-[(2E)-3-Ethyl-2-(ethylimino)-4-oxo-1,3-thiazolidin-5-yl]-N-[3-(trifluoromethyl)phenyl]acetamide

CAS 302548-85-2C₁₆H₁₈F₃N₃O₂S

2-[(2E)-3-Ethyl-2-(ethylimino)-4-oxo-1,3-thiazolidin-5-yl]-N-[2-(trifluoromethyl)phenyl]acetamide chemical structure, C16H18F3N3O2S, CAS 305373-09-5

2-[(2E)-3-Ethyl-2-(ethylimino)-4-oxo-1,3-thiazolidin-5-yl]-N-[2-(trifluoromethyl)phenyl]acetamide

CAS 305373-09-5C₁₆H₁₈F₃N₃O₂S

N-(2-Cyanophenyl)-2-[(2Z)-3-ethyl-2-(ethylimino)-4-oxo-1,3-thiazolidin-5-yl]acetamide chemical structure, C16H18N4O2S, CAS 302804-61-1

N-(2-Cyanophenyl)-2-[(2Z)-3-ethyl-2-(ethylimino)-4-oxo-1,3-thiazolidin-5-yl]acetamide

CAS 302804-61-1C₁₆H₁₈N₄O₂S

(E)-N-(2-Butoxyphenyl)-2-(3-ethyl-2-(ethylimino)-4-oxothiazolidin-5-yl)acetamide chemical structure, C19H27N3O3S, CAS 1164560-79-5

(E)-N-(2-Butoxyphenyl)-2-(3-ethyl-2-(ethylimino)-4-oxothiazolidin-5-yl)acetamide

CAS 1164560-79-5C₁₉H₂₇N₃O₃S

N-[4-(Difluoromethoxy)phenyl]-2-[(2Z)-3-ethyl-2-(ethylimino)-4-oxo-1,3-thiazolidin-5-yl]acetamide chemical structure, C16H19F2N3O3S, CAS 537701-00-1

N-[4-(Difluoromethoxy)phenyl]-2-[(2Z)-3-ethyl-2-(ethylimino)-4-oxo-1,3-thiazolidin-5-yl]acetamide

CAS 537701-00-1C₁₆H₁₉F₂N₃O₃S

3-[2-(3-Methyl-2-methylimino-4-oxo-thiazolidin-5-yl)-acetylamino]-benzoic acid chemical structure, C14H15N3O4S, CAS 514182-28-6

3-[2-(3-Methyl-2-methylimino-4-oxo-thiazolidin-5-yl)-acetylamino]-benzoic acid

CAS 514182-28-6C₁₄H₁₅N₃O₄S

N-(4-Fluorophenyl)-2-(3-methyl-2-methylimino-4-oxo-1,3-thiazolidin-5-yl)acetamide chemical structure, C13H14FN3O2S, CAS 352341-66-3

N-(4-Fluorophenyl)-2-(3-methyl-2-methylimino-4-oxo-1,3-thiazolidin-5-yl)acetamide

CAS 352341-66-3C₁₃H₁₄FN₃O₂S

N-(4-Acetyl-phenyl)-2-(3-ethyl-2-ethylimino-4-oxo-thiazolidin-5-yl)-acetamide chemical structure, C17H21N3O3S, CAS 514182-97-9

N-(4-Acetyl-phenyl)-2-(3-ethyl-2-ethylimino-4-oxo-thiazolidin-5-yl)-acetamide

CAS 514182-97-9C₁₇H₂₁N₃O₃S

2-(3-Methyl-2-methylimino-4-oxo-1,3-thiazolidin-5-yl)-N-(2-methylsulfanylphenyl)acetamide chemical structure, C14H17N3O2S2, CAS 514182-24-2

2-(3-Methyl-2-methylimino-4-oxo-1,3-thiazolidin-5-yl)-N-(2-methylsulfanylphenyl)acetamide

CAS 514182-24-2C₁₄H₁₇N₃O₂S₂

(E)-N-(4-(Dimethylamino)phenyl)-2-(3-methyl-2-(methylimino)-4-oxothiazolidin-5-yl)acetamide chemical structure, C15H20N4O2S, CAS 514182-36-6

(E)-N-(4-(Dimethylamino)phenyl)-2-(3-methyl-2-(methylimino)-4-oxothiazolidin-5-yl)acetamide

CAS 514182-36-6C₁₅H₂₀N₄O₂S

N-(2,4-Dimethylphenyl)-2-(3-methyl-2-methylimino-4-oxo-1,3-thiazolidin-5-yl)acetamide chemical structure, C15H19N3O2S, CAS 514182-53-7

N-(2,4-Dimethylphenyl)-2-(3-methyl-2-methylimino-4-oxo-1,3-thiazolidin-5-yl)acetamide

CAS 514182-53-7C₁₅H₁₉N₃O₂S

N-(2,3-Dimethylphenyl)-2-[(2E)-3-ethyl-2-(ethylimino)-4-oxo-1,3-thiazolidin-5-yl]acetamide chemical structure, C17H23N3O2S, CAS 514183-01-8

N-(2,3-Dimethylphenyl)-2-[(2E)-3-ethyl-2-(ethylimino)-4-oxo-1,3-thiazolidin-5-yl]acetamide

CAS 514183-01-8C₁₇H₂₃N₃O₂S

N-(2-Bromo-4-methylphenyl)-2-(3-methyl-2-methylimino-4-oxo-1,3-thiazolidin-5-yl)acetamide chemical structure, C14H16BrN3O2S, CAS 514182-62-8

N-(2-Bromo-4-methylphenyl)-2-(3-methyl-2-methylimino-4-oxo-1,3-thiazolidin-5-yl)acetamide

CAS 514182-62-8C₁₄H₁₆BrN₃O₂S

N-[4-(Difluoromethoxy)phenyl]-2-[3-methyl-2-(methylimino)-4-oxo-1,3-thiazolidin-5-yl]acetamide chemical structure, C14H15F2N3O3S, CAS 514182-43-5

N-[4-(Difluoromethoxy)phenyl]-2-[3-methyl-2-(methylimino)-4-oxo-1,3-thiazolidin-5-yl]acetamide

CAS 514182-43-5C₁₄H₁₅F₂N₃O₃S

N-(4-Acetyl-phenyl)-2-(3-methyl-2-methylimino-4-oxo-thiazolidin-5-yl)-acetamide chemical structure, C15H17N3O3S, CAS 514182-49-1

N-(4-Acetyl-phenyl)-2-(3-methyl-2-methylimino-4-oxo-thiazolidin-5-yl)-acetamide

CAS 514182-49-1C₁₅H₁₇N₃O₃S

(E)-4-(2-(3-Ethyl-2-(ethylimino)-4-oxothiazolidin-5-yl)acetamido)phenyl acetate chemical structure, C17H21N3O4S, CAS 514182-90-2

(E)-4-(2-(3-Ethyl-2-(ethylimino)-4-oxothiazolidin-5-yl)acetamido)phenyl acetate

CAS 514182-90-2C₁₇H₂₁N₃O₄S

2-[(2E)-3-Ethyl-2-(ethylimino)-4-oxo-1,3-thiazolidin-5-yl]-N-(4-iodophenyl)acetamide chemical structure, C15H18IN3O2S, CAS 514182-88-8

2-[(2E)-3-Ethyl-2-(ethylimino)-4-oxo-1,3-thiazolidin-5-yl]-N-(4-iodophenyl)acetamide

CAS 514182-88-8C₁₅H₁₈IN₃O₂S

N-[4-Chloro-3-(trifluoromethyl)phenyl]-2-[(2Z)-3-ethyl-2-(ethylimino)-4-oxo-1,3-thiazolidin-5-yl]acetamide chemical structure, C16H17ClF3N3O2S, CAS 514183-05-2

N-[4-Chloro-3-(trifluoromethyl)phenyl]-2-[(2Z)-3-ethyl-2-(ethylimino)-4-oxo-1,3-thiazolidin-5-yl]acetamide

CAS 514183-05-2C₁₆H₁₇ClF₃N₃O₂S

2-(3-Methyl-2-methylimino-4-oxo-1,3-thiazolidin-5-yl)-N-[3-(trifluoromethyl)phenyl]acetamide chemical structure, C14H14F3N3O2S, CAS 1164486-20-7

2-(3-Methyl-2-methylimino-4-oxo-1,3-thiazolidin-5-yl)-N-[3-(trifluoromethyl)phenyl]acetamide

CAS 1164486-20-7C₁₄H₁₄F₃N₃O₂S

N-[2-(Difluoromethoxy)phenyl]-2-(3-ethyl-2-ethylimino-4-oxo-1,3-thiazolidin-5-yl)acetamide chemical structure, C16H19F2N3O3S, CAS 514182-86-6

N-[2-(Difluoromethoxy)phenyl]-2-(3-ethyl-2-ethylimino-4-oxo-1,3-thiazolidin-5-yl)acetamide

CAS 514182-86-6C₁₆H₁₉F₂N₃O₃S

N-(2-Ethoxyphenyl)-2-(3-ethyl-2-ethylimino-4-oxo-1,3-thiazolidin-5-yl)acetamide chemical structure, C17H23N3O3S, CAS 1164458-76-7

N-(2-Ethoxyphenyl)-2-(3-ethyl-2-ethylimino-4-oxo-1,3-thiazolidin-5-yl)acetamide

CAS 1164458-76-7C₁₇H₂₃N₃O₃S

2-[(2Z)-3-Ethyl-2-(ethylimino)-4-oxo-1,3-thiazolidin-5-yl]-N-(4-methylphenyl)acetamide chemical structure, C16H21N3O2S, CAS 1164532-57-3

2-[(2Z)-3-Ethyl-2-(ethylimino)-4-oxo-1,3-thiazolidin-5-yl]-N-(4-methylphenyl)acetamide

CAS 1164532-57-3C₁₆H₂₁N₃O₂S