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Murcko scaffold

Ring system with 3 rings and 20 atoms

9 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 20
Chemicals: 9
With full pages: 5

Scaffold SMILES

O=C(Nc1ccccn1)c1conc1-c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C(Nc1ccccn1)c1conc1-c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

3-(2-Chlorophenyl)-5-methyl-N-(5-methylpyridin-2-yl)-1,2-oxazole-4-carboxamide chemical structure, C17H14ClN3O2, CAS 313392-67-5

3-(2-Chlorophenyl)-5-methyl-N-(5-methylpyridin-2-yl)-1,2-oxazole-4-carboxamide

CAS 313392-67-5C₁₇H₁₄ClN₃O₂

3-(2-Chlorophenyl)-N-(5-chloropyridin-2-yl)-5-methyl-1,2-oxazole-4-carboxamide chemical structure, C16H11Cl2N3O2, CAS 349124-76-1

3-(2-Chlorophenyl)-N-(5-chloropyridin-2-yl)-5-methyl-1,2-oxazole-4-carboxamide

CAS 349124-76-1C₁₆H₁₁Cl₂N₃O₂

N-(4,6-Dimethylpyridin-2-yl)-5-methyl-3-phenyl-1,2-oxazole-4-carboxamide chemical structure, C18H17N3O2, CAS 352681-73-3

N-(4,6-Dimethylpyridin-2-yl)-5-methyl-3-phenyl-1,2-oxazole-4-carboxamide

CAS 352681-73-3C₁₈H₁₇N₃O₂

5-Methyl-N-(6-methylpyridin-2-yl)-3-phenyl-1,2-oxazole-4-carboxamide chemical structure, C17H15N3O2, CAS 550305-35-6

5-Methyl-N-(6-methylpyridin-2-yl)-3-phenyl-1,2-oxazole-4-carboxamide

CAS 550305-35-6C₁₇H₁₅N₃O₂

3-(2-Chloro-6-fluorophenyl)-5-methyl-N-(5-methylpyridin-2-yl)-1,2-oxazole-4-carboxamide chemical structure, C17H13ClFN3O2, CAS 515872-51-2

3-(2-Chloro-6-fluorophenyl)-5-methyl-N-(5-methylpyridin-2-yl)-1,2-oxazole-4-carboxamide

CAS 515872-51-2C₁₇H₁₃ClFN₃O₂

3-(2,6-Dichlorophenyl)-N-(4,6-dimethylpyridin-2-yl)-5-methyl-1,2-oxazole-4-carboxamide chemical structure, C18H15Cl2N3O2, CAS 419559-56-1

3-(2,6-Dichlorophenyl)-N-(4,6-dimethylpyridin-2-yl)-5-methyl-1,2-oxazole-4-carboxamide

CAS 419559-56-1C₁₈H₁₅Cl₂N₃O₂

N-(5-Chloropyridin-2-yl)-3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazole-4-carboxamide chemical structure, C16H10Cl3N3O2, CAS 349124-77-2

N-(5-Chloropyridin-2-yl)-3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazole-4-carboxamide

CAS 349124-77-2C₁₆H₁₀Cl₃N₃O₂

N-(5-Bromopyridin-2-yl)-3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazole-4-carboxamide chemical structure, C16H10BrCl2N3O2, CAS 652965-63-4

N-(5-Bromopyridin-2-yl)-3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazole-4-carboxamide

CAS 652965-63-4C₁₆H₁₀BrCl₂N₃O₂

N-(5-Bromopyridin-2-yl)-3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-carboxamide chemical structure, C16H11BrClN3O2, CAS 1022731-48-1

N-(5-Bromopyridin-2-yl)-3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-carboxamide

CAS 1022731-48-1C₁₆H₁₁BrClN₃O₂