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Murcko scaffold

Ring system with 2 rings and 16 atoms

12 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
16
Chemicals
12
With full pages
7
Scaffold SMILES

O=C(CSc1ccccc1)Nc1ccsc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CSc1ccccc1)Nc1ccsc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

Methyl 3-({[(4-chlorophenyl)sulfanyl]acetyl}amino)-2-thiophenecarboxylate chemical structure, C14H12ClNO3S2, CAS 477887-66-4
Methyl 3-({[(4-chlorophenyl)sulfanyl]acetyl}amino)-2-thiophenecarboxylate
CAS 477887-66-4C14H12ClNO3S2
Methyl 3-({2-[(2-aminophenyl)sulfanyl]acetyl}amino)-2-thiophenecarboxylate chemical structure, C14H14N2O3S2, CAS 477869-07-1
Methyl 3-({2-[(2-aminophenyl)sulfanyl]acetyl}amino)-2-thiophenecarboxylate
CAS 477869-07-1C14H14N2O3S2
Methyl 3-[(2-{[2-(methoxycarbonyl)phenyl]sulfanyl}acetyl)amino]-2-thiophenecarboxylate chemical structure, C16H15NO5S2, CAS 477869-13-9
Methyl 3-[(2-{[2-(methoxycarbonyl)phenyl]sulfanyl}acetyl)amino]-2-thiophenecarboxylate
CAS 477869-13-9C16H15NO5S2
Methyl 3-({2-[(4-bromophenyl)sulfanyl]acetyl}amino)-2-thiophenecarboxylate chemical structure, C14H12BrNO3S2, CAS 477869-14-0
Methyl 3-({2-[(4-bromophenyl)sulfanyl]acetyl}amino)-2-thiophenecarboxylate
CAS 477869-14-0C14H12BrNO3S2
Methyl 3-[2-(phenylsulfanyl)acetamido]thiophene-2-carboxylate chemical structure, C14H13NO3S2, CAS 830340-37-9
Methyl 3-[2-(phenylsulfanyl)acetamido]thiophene-2-carboxylate
CAS 830340-37-9C14H13NO3S2
Methyl 3-({2-[(2,3-dichlorophenyl)sulfanyl]acetyl}amino)-2-thiophenecarboxylate chemical structure, C14H11Cl2NO3S2, CAS 477887-64-2
Methyl 3-({2-[(2,3-dichlorophenyl)sulfanyl]acetyl}amino)-2-thiophenecarboxylate
CAS 477887-64-2C14H11Cl2NO3S2
Methyl 3-({2-[(2-{[2-(diethylamino)acetyl]amino}phenyl)sulfanyl]acetyl}amino)-2-thiophenecarboxylate chemical structure, C20H25N3O4S2, CAS 478045-06-6
Methyl 3-({2-[(2-{[2-(diethylamino)acetyl]amino}phenyl)sulfanyl]acetyl}amino)-2-thiophenecarboxylate
CAS 478045-06-6C20H25N3O4S2
Methyl 3-({2-[(2-{[2-(allylamino)acetyl]amino}phenyl)sulfanyl]acetyl}amino)-2-thiophenecarboxylate chemical structure, C19H21N3O4S2, CAS 866017-59-6
Methyl 3-({2-[(2-{[2-(allylamino)acetyl]amino}phenyl)sulfanyl]acetyl}amino)-2-thiophenecarboxylate
CAS 866017-59-6C19H21N3O4S2
Methyl 3-({2-[(2-{[2-(isopropylamino)acetyl]amino}phenyl)sulfanyl]acetyl}amino)-2-thiophenecarboxylate chemical structure, C19H23N3O4S2, CAS 478045-25-9
Methyl 3-({2-[(2-{[2-(isopropylamino)acetyl]amino}phenyl)sulfanyl]acetyl}amino)-2-thiophenecarboxylate
CAS 478045-25-9C19H23N3O4S2
Methyl 3-({2-[(2,5-dichlorophenyl)sulfanyl]acetyl}amino)-2-thiophenecarboxylate chemical structure, C14H11Cl2NO3S2, CAS 477887-65-3
Methyl 3-({2-[(2,5-dichlorophenyl)sulfanyl]acetyl}amino)-2-thiophenecarboxylate
CAS 477887-65-3C14H11Cl2NO3S2
Methyl 3-({[(3-chlorophenyl)sulfanyl]acetyl}amino)-2-thiophenecarboxylate chemical structure, C14H12ClNO3S2, CAS 353266-59-8
Methyl 3-({[(3-chlorophenyl)sulfanyl]acetyl}amino)-2-thiophenecarboxylate
CAS 353266-59-8C14H12ClNO3S2
2-[({[2-(Methoxycarbonyl)thiophen-3-yl]carbamoyl}methyl)sulfanyl]benzoic acid chemical structure, C15H13NO5S2, CAS 923558-53-6
2-[({[2-(Methoxycarbonyl)thiophen-3-yl]carbamoyl}methyl)sulfanyl]benzoic acid
CAS 923558-53-6C15H13NO5S2