Murcko scaffold
N-(2-Phenylethyl)-1-benzofuran-2-carboxamide scaffold
35 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 20
- Chemicals
- 35
- With full pages
- 5
Scaffold SMILES
O=C(NCCc1ccccc1)c1cc2ccccc2o1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 35 of 35 chemicals
![N-[2-(3,4-Dimethoxyphenyl)ethyl]-1-benzofuran-2-carboxamide chemical structure, C19H19NO4, CAS 304889-22-3](/s/ICGLDNFIXLBXNV-UHFFFAOYSA-N.svg)
N-[2-(3,4-Dimethoxyphenyl)ethyl]-1-benzofuran-2-carboxamide
CAS 304889-22-3C19H19NO4
N-(2-Phenylethyl)-1-benzofuran-2-carboxamide
CAS 50635-14-8C17H15NO2
![N-[2-(3,4-Dimethoxyphenyl)ethyl]-3-methyl-1-benzofuran-2-carboxamide chemical structure, C20H21NO4, CAS 381178-75-2](/s/HAJNUQVFVOPXFD-UHFFFAOYSA-N.svg)
N-[2-(3,4-Dimethoxyphenyl)ethyl]-3-methyl-1-benzofuran-2-carboxamide
CAS 381178-75-2C20H21NO4
3-Methyl-N-(2-phenylethyl)-1-benzofuran-2-carboxamide
CAS 842958-72-9C18H17NO2
![N-[2-(3,4-Dimethoxyphenyl)ethyl]-3,5,6-trimethyl-1-benzofuran-2-carboxamide chemical structure, C22H25NO4, CAS 622349-34-2](/s/WEDNBJFJLNUCGZ-UHFFFAOYSA-N.svg)
N-[2-(3,4-Dimethoxyphenyl)ethyl]-3,5,6-trimethyl-1-benzofuran-2-carboxamide
CAS 622349-34-2C22H25NO4
![3,5,6-Trimethyl-N-[2-(4-sulfamoylphenyl)ethyl]-1-benzofuran-2-carboxamide chemical structure, C20H22N2O4S, CAS 622350-04-3](/s/JVRTZMWOXKMABX-UHFFFAOYSA-N.svg)
3,5,6-Trimethyl-N-[2-(4-sulfamoylphenyl)ethyl]-1-benzofuran-2-carboxamide
CAS 622350-04-3C20H22N2O4S
![N-[2-(3,4-Dimethoxyphenyl)ethyl]-3,5-dimethyl-1-benzofuran-2-carboxamide chemical structure, C21H23NO4, CAS 620587-58-8](/s/MHAIMAMFIKNWMO-UHFFFAOYSA-N.svg)
N-[2-(3,4-Dimethoxyphenyl)ethyl]-3,5-dimethyl-1-benzofuran-2-carboxamide
CAS 620587-58-8C21H23NO4
![5-Chloro-N-[2-(3,4-dimethoxyphenyl)ethyl]-3-methyl-1-benzofuran-2-carboxamide chemical structure, C20H20ClNO4, CAS 714261-37-7](/s/VRQFUXAAZNSATK-UHFFFAOYSA-N.svg)
5-Chloro-N-[2-(3,4-dimethoxyphenyl)ethyl]-3-methyl-1-benzofuran-2-carboxamide
CAS 714261-37-7C20H20ClNO4
7-Methoxy-N-(2-phenylethyl)-1-benzofuran-2-carboxamide
CAS 207561-45-3C18H17NO3
![5-Fluoro-3-methyl-N-[2-(4-sulfamoylphenyl)ethyl]-1-benzofuran-2-carboxamide chemical structure, C18H17FN2O4S, CAS 919074-43-4](/s/BTFHJAQQVOCVEW-UHFFFAOYSA-N.svg)
5-Fluoro-3-methyl-N-[2-(4-sulfamoylphenyl)ethyl]-1-benzofuran-2-carboxamide
CAS 919074-43-4C18H17FN2O4S
![4-{2-[(1-Benzofuran-2-carbonyl)amino]ethyl}benzene-1-sulfonyl chloride chemical structure, C17H14ClNO4S, CAS 90141-24-5](/s/UEJDDHYVOOMRPS-UHFFFAOYSA-N.svg)
4-{2-[(1-Benzofuran-2-carbonyl)amino]ethyl}benzene-1-sulfonyl chloride
CAS 90141-24-5C17H14ClNO4S
![N-[2-(Dimethylamino)-2-(2-methoxyphenyl)ethyl]-3,5,6-trimethyl-1-benzofuran-2-carboxamide chemical structure, C23H28N2O3, CAS 874147-94-1](/s/QHFUGKPXHHDJRO-UHFFFAOYSA-N.svg)
N-[2-(Dimethylamino)-2-(2-methoxyphenyl)ethyl]-3,5,6-trimethyl-1-benzofuran-2-carboxamide
CAS 874147-94-1C23H28N2O3
![5-Chloro-N-[2-(dimethylamino)-2-(2-methoxyphenyl)ethyl]-3-methyl-1-benzofuran-2-carboxamide chemical structure, C21H23ClN2O3, CAS 874148-15-9](/s/SUUFFJDFIFISSF-UHFFFAOYSA-N.svg)
5-Chloro-N-[2-(dimethylamino)-2-(2-methoxyphenyl)ethyl]-3-methyl-1-benzofuran-2-carboxamide
CAS 874148-15-9C21H23ClN2O3
![5-Chloro-N-[2-(dimethylamino)-2-(2-methoxyphenyl)ethyl]-3,6-dimethyl-1-benzofuran-2-carboxamide chemical structure, C22H25ClN2O3, CAS 898514-72-2](/s/WGJOOBHPEIXHSB-UHFFFAOYSA-N.svg)
5-Chloro-N-[2-(dimethylamino)-2-(2-methoxyphenyl)ethyl]-3,6-dimethyl-1-benzofuran-2-carboxamide
CAS 898514-72-2C22H25ClN2O3
![N-[2-(3,4-Dimethoxyphenyl)ethyl]-3,6-dimethyl-1-benzofuran-2-carboxamide chemical structure, C21H23NO4, CAS 912898-54-5](/s/IKYISKBYNMREPN-UHFFFAOYSA-N.svg)
N-[2-(3,4-Dimethoxyphenyl)ethyl]-3,6-dimethyl-1-benzofuran-2-carboxamide
CAS 912898-54-5C21H23NO4
5-Chloro-N-(1-cyano-2-phenylethyl)-1-benzofuran-2-carboxamide
CAS 1240897-87-3C18H13ClN2O2
N-(3,3,3-Trifluoro-2-hydroxy-2-phenylpropyl)benzofuran-2-carboxamide
CAS 1351615-87-6C18H14F3NO3
7-Methoxy-N-(3,3,3-trifluoro-2-hydroxy-2-phenylpropyl)benzofuran-2-carboxamide
CAS 1351605-15-6C19H16F3NO4
N-(2-Hydroxy-2-phenylpropyl)benzofuran-2-carboxamide
CAS 1351622-50-8C18H17NO3
N-(2-Hydroxy-2-(4-(trifluoromethyl)phenyl)ethyl)-7-methoxybenzofuran-2-carboxamide
CAS 1351619-00-5C19H16F3NO4
N-(2-(4-(Dimethylamino)phenyl)-2-hydroxyethyl)benzofuran-2-carboxamide
CAS 1421529-79-4C19H20N2O3
N-(2-(4-(Dimethylamino)phenyl)-2-hydroxyethyl)-7-methoxybenzofuran-2-carboxamide
CAS 1421466-15-0C20H22N2O4
N-(2-Hydroxy-2-(4-(methylthio)phenyl)ethyl)benzofuran-2-carboxamide
CAS 1448047-51-5C18H17NO3S
N-(2-Hydroxy-2-(4-(methylthio)phenyl)ethyl)-7-methoxybenzofuran-2-carboxamide
CAS 1448044-89-0C19H19NO4S
- 7-Methoxy-N-(2-methoxy-2-(o-tolyl)ethyl)benzofuran-2-carboxamide1797183-63-1C20H21NO4
- N-(2-(2-Fluorophenyl)-2-methoxypropyl)-7-methoxybenzofuran-2-carboxamide1797339-29-7C20H20FNO4
- N-(2-(3-Fluorophenyl)-2-methoxyethyl)-7-methoxybenzofuran-2-carboxamide1796949-55-7C19H18FNO4
- N-(2-Methoxy-2-(3-methoxyphenyl)ethyl)benzofuran-2-carboxamide1797355-20-4C19H19NO4
- N-(2-(2-Hydroxyethoxy)-2-(p-tolyl)ethyl)-7-methoxybenzofuran-2-carboxamide1787903-29-0C21H23NO5
- 7-Methoxy-N-(2-methoxy-2-(2-methoxyphenyl)ethyl)benzofuran-2-carboxamide1795299-68-1C20H21NO5
- N-(2-(2-Chlorophenyl)-2-methoxyethyl)benzofuran-2-carboxamide1795420-04-0C18H16ClNO3
- N-(2-(3-Chlorophenyl)-2-methoxypropyl)benzofuran-2-carboxamide1788677-44-0C19H18ClNO3
- N-(2-(3-Chlorophenyl)-2-methoxypropyl)-7-methoxybenzofuran-2-carboxamide1795196-83-6C20H20ClNO4
- N-(2-Methoxy-2-phenylbutyl)benzofuran-2-carboxamide1706014-70-1C20H21NO3
- N-(2-(3-Fluorophenyl)-2-methoxyethyl)benzofuran-2-carboxamide1705100-35-1C18H16FNO3
Related scaffolds
Same ring framework with different atoms or bond orders
![Scaffold O=C(CSc1nc2ccccc2[nH]1)Nc1ccccc1](/scaffold/WVWIDWYWASPVGN-UHFFFAOYSA-N/structure.svg)
O=C(CSc1nc2ccccc2[nH]1)Nc1ccccc149 chemicals![Scaffold c1ccc(OCCSc2nc3ccccc3[nH]2)cc1](/scaffold/UEYUFQWEHMSHIX-UHFFFAOYSA-N/structure.svg)
c1ccc(OCCSc2nc3ccccc3[nH]2)cc136 chemicals![Scaffold O=C(NCCc1nc2ccccc2[nH]1)c1ccccc1](/scaffold/YRGGTYXDASSWSH-UHFFFAOYSA-N/structure.svg)
O=C(NCCc1nc2ccccc2[nH]1)c1ccccc124 chemicals
O=C(COc1ccccc1)Nc1nc2ccccc2s122 chemicals
O=C(COc1ccccc1)Nc1cc2c(s1)CCCC220 chemicals
O=C(CCN1C(=O)c2ccccc2S1(=O)=O)Nc1ccccc119 chemicals
O=C(CCN1C(=O)c2ccccc2C1=O)Nc1ccccc118 chemicals
O=C(CS(=O)(=O)c1ccccc1)Nc1nc2ccccc2s117 chemicals
O=C(CSc1nc2ccccc2s1)Nc1ccccc114 chemicals![Scaffold O=C(NN=Cc1ccccc1)c1cc2ccccc2[nH]1](/scaffold/SYUQFFCOGGAGKC-UHFFFAOYSA-N/structure.svg)
O=C(NN=Cc1ccccc1)c1cc2ccccc2[nH]113 chemicals
O=C(CN1C(=O)c2ccccc2C1=O)NCc1ccccc111 chemicals
O=C(CN1C(=O)c2ccccc2S1(=O)=O)NCc1ccccc111 chemicals