CompoundList
Sign in
Murcko scaffold

N-Cyclohexyl-2-[(4-oxo-1H-quinazolin-2-yl)sulfanyl]acetamide scaffold

12 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
12
With full pages
4
Scaffold SMILES

O=C(CSc1nc2ccccc2c(=O)[nH]1)NC1CCCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-Cyclohexyl-2-[(4-oxo-1H-quinazolin-2-yl)sulfanyl]acetamide page
Murcko scaffold O=C(CSc1nc2ccccc2c(=O)[nH]1)NC1CCCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

N-Cyclohexyl-2-(3-ethyl-4-oxoquinazolin-2-yl)sulfanylacetamide chemical structure, C18H23N3O2S, CAS 702648-67-7
N-Cyclohexyl-2-(3-ethyl-4-oxoquinazolin-2-yl)sulfanylacetamide
CAS 702648-67-7C18H23N3O2S
N-(1-Cyanocyclohexyl)-2-[3-(2-methoxyethyl)-4-oxoquinazolin-2-yl]sulfanylacetamide chemical structure, C20H24N4O3S, CAS 852224-33-0
N-(1-Cyanocyclohexyl)-2-[3-(2-methoxyethyl)-4-oxoquinazolin-2-yl]sulfanylacetamide
CAS 852224-33-0C20H24N4O3S
N-(1-Cyanocyclohexyl)-2-((3-(1-methoxypropan-2-yl)-4-oxo-3,4-dihydroquinazolin-2-yl)thio)propanamide chemical structure, C22H28N4O3S, CAS 847746-72-9
N-(1-Cyanocyclohexyl)-2-((3-(1-methoxypropan-2-yl)-4-oxo-3,4-dihydroquinazolin-2-yl)thio)propanamide
CAS 847746-72-9C22H28N4O3S
N-(1-Cyanocyclohexyl)-2-((3-(3-ethoxypropyl)-4-oxo-3,4-dihydroquinazolin-2-yl)thio)acetamide chemical structure, C22H28N4O3S, CAS 847753-59-7
N-(1-Cyanocyclohexyl)-2-((3-(3-ethoxypropyl)-4-oxo-3,4-dihydroquinazolin-2-yl)thio)acetamide
CAS 847753-59-7C22H28N4O3S
2-((3-Allyl-4-oxo-3,4-dihydroquinazolin-2-yl)thio)-N-(1-cyanocyclohexyl)acetamide chemical structure, C20H22N4O2S, CAS 849685-58-1
2-((3-Allyl-4-oxo-3,4-dihydroquinazolin-2-yl)thio)-N-(1-cyanocyclohexyl)acetamide
CAS 849685-58-1C20H22N4O2S
N-(2,3-Dimethylcyclohexyl)-2-[3-(2-methylpropyl)-4-oxoquinazolin-2-yl]sulfanylacetamide chemical structure, C22H31N3O2S, CAS 5666-87-5
N-(2,3-Dimethylcyclohexyl)-2-[3-(2-methylpropyl)-4-oxoquinazolin-2-yl]sulfanylacetamide
CAS 5666-87-5C22H31N3O2S
N-(1-Cyanocyclohexyl)-2-[(3-ethyl-4-oxo-3,4-dihydroquinazolin-2-yl)sulfanyl]acetamide chemical structure, C19H22N4O2S, CAS 1016488-68-8
N-(1-Cyanocyclohexyl)-2-[(3-ethyl-4-oxo-3,4-dihydroquinazolin-2-yl)sulfanyl]acetamide
CAS 1016488-68-8C19H22N4O2S
N-(1-Cyanocyclohexyl)-2-{[4-oxo-3-(propan-2-yl)-3,4-dihydroquinazolin-2-yl]sulfanyl}acetamide chemical structure, C20H24N4O2S, CAS 1117803-62-9
N-(1-Cyanocyclohexyl)-2-{[4-oxo-3-(propan-2-yl)-3,4-dihydroquinazolin-2-yl]sulfanyl}acetamide
CAS 1117803-62-9C20H24N4O2S
2-{[6-Chloro-3-(2-methylpropyl)-4-oxo-3,4-dihydroquinazolin-2-yl]sulfanyl}-N-(1-cyanocyclohexyl)propanamide chemical structure, C22H27ClN4O2S, CAS 938610-15-2
2-{[6-Chloro-3-(2-methylpropyl)-4-oxo-3,4-dihydroquinazolin-2-yl]sulfanyl}-N-(1-cyanocyclohexyl)propanamide
CAS 938610-15-2C22H27ClN4O2S
N-(1-Cyanocyclohexyl)-2-[(3,6-dimethyl-4-oxo-3,4-dihydroquinazolin-2-yl)sulfanyl]acetamide chemical structure, C19H22N4O2S, CAS 1223171-89-8
N-(1-Cyanocyclohexyl)-2-[(3,6-dimethyl-4-oxo-3,4-dihydroquinazolin-2-yl)sulfanyl]acetamide
CAS 1223171-89-8C19H22N4O2S
N-Cyclohexyl-2-[(4-oxo-1H-quinazolin-2-yl)sulfanyl]acetamide chemical structure, C16H19N3O2S, CAS 77517-26-1
N-Cyclohexyl-2-[(4-oxo-1H-quinazolin-2-yl)sulfanyl]acetamide
CAS 77517-26-1C16H19N3O2S
N-Cyclohexyl-2-[(5-fluoro-4-oxo-3H-quinazolin-2-yl)sulfanyl]acetamide chemical structure, C16H18FN3O2S, CAS 2225883-59-8
N-Cyclohexyl-2-[(5-fluoro-4-oxo-3H-quinazolin-2-yl)sulfanyl]acetamide
CAS 2225883-59-8C16H18FN3O2S