Murcko scaffold
1,3-Diazaspiro(4.4)nonane-2,4-dione scaffold
58 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 11
- Chemicals
- 58
- With full pages
- 15
Scaffold SMILES
O=C1NC(=O)C2(CCCC2)N1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 58 chemicals
1,3-Diazaspiro(4.4)nonane-2,4-dione, 3-(2-hydroxyethyl)-
CAS 710-88-3C9H14N2O3
1,3-Diazaspiro(4.4)nonane-2,4-dione, 3-(hydroxymethyl)-
CAS 878-52-4C8H12N2O3
1,3-Diazaspiro(4.4)nonane-2,4-dione
CAS 699-51-4C7H10N2O2
1-Acetyl-1,3-diazaspiro(4.4)nonane-2,4-dione
CAS 1012-35-7C9H12N2O3
Cypenhymustine
CAS 150380-35-1C13H21Cl2N3O2
![3-Methyl-1,3-diazaspiro[4.4]nonane-2,4-dione chemical structure, C8H12N2O2, CAS 5455-37-8](/s/HUNUBQWRKXDKMX-UHFFFAOYSA-N.svg)
3-Methyl-1,3-diazaspiro[4.4]nonane-2,4-dione
CAS 5455-37-8C8H12N2O2
![6-Methyl-1,3-diazaspiro[4.4]nonane-2,4-dione chemical structure, C8H12N2O2, CAS 90434-66-5](/s/BLUBYZQXVVYGLV-UHFFFAOYSA-N.svg)
6-Methyl-1,3-diazaspiro[4.4]nonane-2,4-dione
CAS 90434-66-5C8H12N2O2
![6-Propyl-1,3-diazaspiro[4.4]nonane-2,4-dione chemical structure, C10H16N2O2, CAS 27738-07-4](/s/HUXKMYNZLFKGKO-UHFFFAOYSA-N.svg)
6-Propyl-1,3-diazaspiro[4.4]nonane-2,4-dione
CAS 27738-07-4C10H16N2O2
![9-(2-Methylpropyl)-1,3-diazaspiro[4.4]nonane-2,4-dione chemical structure, C11H18N2O2, CAS 6266-06-4](/s/KVBWBUMNECFZSJ-UHFFFAOYSA-N.svg)
9-(2-Methylpropyl)-1,3-diazaspiro[4.4]nonane-2,4-dione
CAS 6266-06-4C11H18N2O2
2,4-Dioxo-1,3-diazaspiro(4.4)nonane-6-carboxylic acid
CAS 7153-58-4C8H10N2O4
![rel-(5R,7R)-2,4-Dioxo-1,3-diazaspiro[4.4]nonane-7-carboxylic acid chemical structure, C8H10N2O4, CAS 122743-40-2](/s/IDLOULSKJDVSKX-SPGJFGJESA-N.svg)
rel-(5R,7R)-2,4-Dioxo-1,3-diazaspiro[4.4]nonane-7-carboxylic acid
CAS 122743-40-2C8H10N2O4
3-(2,4-Dioxo-1,3-diazaspiro(4.4)nonan-3-yl)propanoic acid
CAS 852400-00-1C10H14N2O4
![2,4-Dioxo-1,3-diazaspiro[4.4]nonane-7-carboxylic acid chemical structure, C8H10N2O4, CAS 352656-69-0](/s/IDLOULSKJDVSKX-UHFFFAOYSA-N.svg)
2,4-Dioxo-1,3-diazaspiro[4.4]nonane-7-carboxylic acid
CAS 352656-69-0C8H10N2O4
![2-(2,4-Dioxo-1,3-diazaspiro[4.4]non-3-yl)-N-(3-methylbutyl)acetamide chemical structure, C14H23N3O3, CAS 731012-77-4](/s/NHCBODBBDXWSKL-UHFFFAOYSA-N.svg)
2-(2,4-Dioxo-1,3-diazaspiro[4.4]non-3-yl)-N-(3-methylbutyl)acetamide
CAS 731012-77-4C14H23N3O3
![4-{2,4-Dioxo-1,3-diazaspiro[4.4]nonan-3-yl}butanoic acid chemical structure, C11H16N2O4, CAS 853574-48-8](/s/FWUBSDVRUFJATF-UHFFFAOYSA-N.svg)
4-{2,4-Dioxo-1,3-diazaspiro[4.4]nonan-3-yl}butanoic acid
CAS 853574-48-8C11H16N2O4
2-(2,4-Dioxo-1,3-diazaspiro(4.4)nonan-3-yl)acetic acid
CAS 714-72-7C9H12N2O4
Spiriprostil
CAS 122946-42-3C20H34N2O4
![3-Amino-1,3-diazaspiro[4.4]nonane-2,4-dione chemical structure, C7H11N3O2, CAS 16252-62-3](/s/XWUJSAXHQJZQCG-UHFFFAOYSA-N.svg)
3-Amino-1,3-diazaspiro[4.4]nonane-2,4-dione
CAS 16252-62-3C7H11N3O2
![2-(2,4-Dioxo-1,3-diazaspiro[4.4]nonan-3-yl)acetamide chemical structure, C9H13N3O3, CAS 882-68-8](/s/PNOSDAFFACGUQB-UHFFFAOYSA-N.svg)
2-(2,4-Dioxo-1,3-diazaspiro[4.4]nonan-3-yl)acetamide
CAS 882-68-8C9H13N3O3
![2-{2,4-Dioxo-1,3-diazaspiro[4.4]nonan-3-yl}ethane-1-sulfonyl fluoride chemical structure, C9H13FN2O4S, CAS 885527-09-3](/s/TTWNFNRBVOYMBP-UHFFFAOYSA-N.svg)
2-{2,4-Dioxo-1,3-diazaspiro[4.4]nonan-3-yl}ethane-1-sulfonyl fluoride
CAS 885527-09-3C9H13FN2O4S
![2-{2,4-Dioxo-1,3-diazaspiro[4.4]nonan-3-yl}propanoic acid chemical structure, C10H14N2O4, CAS 926195-36-0](/s/VLCOWQPLEBOIIE-UHFFFAOYSA-N.svg)
2-{2,4-Dioxo-1,3-diazaspiro[4.4]nonan-3-yl}propanoic acid
CAS 926195-36-0C10H14N2O4
![3-{2,4-Dioxo-1,3-diazaspiro[4.4]nonan-3-yl}propanenitrile chemical structure, C10H13N3O2, CAS 897282-01-8](/s/PGESNTIBOXIKOR-UHFFFAOYSA-N.svg)
3-{2,4-Dioxo-1,3-diazaspiro[4.4]nonan-3-yl}propanenitrile
CAS 897282-01-8C10H13N3O2
Ibi-P 01028
CAS 137822-20-9C20H33N2NaO4
3-(2-Bromoethyl)-1,3-diazaspiro(4.4)nonane-2,4-dione
CAS 150259-29-3C9H13BrN2O2
- (2,4-Dioxo-1,3-diazaspiro[4.4]non-3-yl)-acetonitrile1016835-29-2C9H11N3O2
- 3-(3-Aminopropyl)-1,3-diazaspiro(4.4)nonane-2,4-dione1018185-30-2C10H17N3O2
- N-(1-Cyano-1,2-dimethylpropyl)-2-{2,4-dioxo-1,3-diazaspiro[4.4]nonan-3-yl}acetamide1147351-97-0C15H22N4O3
- 1-Methyl-1,3-diazaspiro[4.4]nonane-2,4-dione1170110-01-6C8H12N2O2
- 3-{2,4-Dioxo-1,3-diazaspiro[4.4]nonan-3-yl}propanamide1248735-80-9C10H15N3O3
- 6-(Aminomethyl)-1,3-diazaspiro(4.4)nonane-2,4-dione hydrochloride1354961-90-2C8H14ClN3O2
- 6-(Aminomethyl)-1,3-diazaspiro[4.4]nonane-2,4-dione1355004-86-2C8H13N3O2
- 7-(Prop-2-en-1-yl)-1,3-diazaspiro[4.4]nonane-2,4-dione906456-04-0C10H14N2O2
- 7-Ethenyl-1,3-diazaspiro[4.4]nonane-2,4-dione906456-05-1C9H12N2O2
- 1-(2-Aminoethyl)-1,3-diazaspiro[4.4]nonane-2,4-dione893433-63-1C9H15N3O2
- 3-{2,4-Dioxo-1,3-diazaspiro[4.4]nonan-3-yl}-2-hydroxy-2-methylpropanoic acid1477817-59-6C11H16N2O5
- 6-(Aminomethyl)-3-methyl-1,3-diazaspiro[4.4]nonane-2,4-dione hydrochloride1375473-41-8C9H16ClN3O2
- 6-(Aminomethyl)-3-methyl-1,3-diazaspiro[4.4]nonane-2,4-dione1375794-80-1C9H15N3O2
- N-(1-Cyanobutyl)-4-{2,4-dioxo-1,3-diazaspiro[4.4]nonan-3-yl}butanamide1445109-34-1C16H24N4O3
- 3-(4-Aminobutyl)-1,3-diazaspiro(4.4)nonane-2,4-dione hydrochloride1803606-52-1C11H20ClN3O2
- 3-(2-Aminoethyl)-1,3-diazaspiro[4.4]nonane-2,4-dione hydrochloride1803581-03-4C9H16ClN3O2
- 6,6-Dimethyl-1,3-diazaspiro[4.4]nonane-2,4-dione90565-74-5C9H14N2O2
- 7,7-Dimethyl-1,3-diazaspiro[4.4]nonane-2,4-dione1536184-51-6C9H14N2O2
- 2,4-Dioxo-1,3-diazaspiro[4.4]nonane-6-carboxylic acid ethyl ester3560-50-7C10H14N2O4
- Methyl (5S,8R)-2,4-dioxo-1,3-diazaspiro[4.4]nonane-8-carboxylate2377004-96-9C9H12N2O4
- 6-Amino-1,3-diazaspiro[4.4]nonane-2,4-dione477584-10-4C7H11N3O2
- 2-{2,4-Dioxo-1,3-diazaspiro[4.4]nonan-3-yl}ethane-1-sulfonyl chloride2090739-27-6C9H13ClN2O4S
- 2-Chloro-N-[(2,4-dioxo-1,3-diazaspiro[4.4]nonan-9-yl)methyl]propanamide2411256-88-5C11H16ClN3O3
- N-(3-{2,4-Dioxo-1,3-diazaspiro[4.4]nonan-3-yl}propyl)prop-2-enamide2361764-88-5C13H19N3O3
Related scaffolds
Same ring framework with different atoms or bond orders
C1CCC2(C1)CCNC227 chemicals
C1CCC2(C1)CCCN213 chemicals
C1CCC2(C1)OCCO29 chemicals
C1CCC2(C1)CCCC29 chemicals
C1CC2(CCNC2)CN17 chemicals
C1CC2(CN1)OCCO27 chemicals
C1CCC2(C1)CCCO26 chemicals
C1CC2(CCOC2)CN16 chemicals![Scaffold C1CC[N+]2(C1)CCCC2](/scaffold/NZSICTQUKULOSA-UHFFFAOYSA-N/structure.svg)
C1CC[N+]2(C1)CCCC25 chemicals
C1COC2(C1)CCOC24 chemicals
C1CNC2(C1)CCNC24 chemicals
O=C1NC(=O)C2(CCNC2)N14 chemicals