Murcko scaffold
1-Azaspiro(4.4)nonane scaffold
99 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 9
- Chemicals
- 99
- With full pages
- 13
Scaffold SMILES
C1CCC2(C1)CCCN2
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 99 chemicals
![(7R,8R)-7,8-Dimethyl-1-azaspiro[4.4]nonane chemical structure, C10H19N, CAS 1059637-11-4](/s/JQXLMQXLNVVUDS-RKDXNWHRSA-N.svg)
(7R,8R)-7,8-Dimethyl-1-azaspiro[4.4]nonane
CAS 1059637-11-4C10H19N
![7,8-Dimethyl-1-azaspiro[4.4]nonane chemical structure, C10H19N](/s/JQXLMQXLNVVUDS-UHFFFAOYSA-N.svg)
7,8-Dimethyl-1-azaspiro[4.4]nonane
C10H19N
![1-Azaspiro[4.4]nonane-2-carboxylic acid chemical structure, C9H15NO2, CAS 96798-47-9](/s/ZXMYUPJTDAGGFW-UHFFFAOYSA-N.svg)
1-Azaspiro[4.4]nonane-2-carboxylic acid
CAS 96798-47-9C9H15NO2
1-Azaspiro(4.4)nonane
CAS 176-03-4C8H15N
![7,8-Dimethyl-1-azaspiro[4.4]nonane hydrochloride chemical structure, C10H20ClN, CAS 959579-91-0](/s/YOEKDAXNEUTRHF-UHFFFAOYSA-N.svg)
7,8-Dimethyl-1-azaspiro[4.4]nonane hydrochloride
CAS 959579-91-0C10H20ClN
![1-Methyl-1-azaspiro[4.4]nonan-4-ol chemical structure, C9H17NO, CAS 94624-90-5](/s/VECFOENRHVJECN-UHFFFAOYSA-N.svg)
1-Methyl-1-azaspiro[4.4]nonan-4-ol
CAS 94624-90-5C9H17NO
![(5S,9S)-1-Azaspiro[4.4]nonan-9-ol chemical structure, C8H15NO, CAS 1787263-80-2](/s/XQEIGYONVMVHCT-YUMQZZPRSA-N.svg)
(5S,9S)-1-Azaspiro[4.4]nonan-9-ol
CAS 1787263-80-2C8H15NO
![1-Azaspiro[4.4]nonane-4-carboxylic acid chemical structure, C9H15NO2, CAS 1557020-59-3](/s/YJXKZUVKUXYUIZ-UHFFFAOYSA-N.svg)
1-Azaspiro[4.4]nonane-4-carboxylic acid
CAS 1557020-59-3C9H15NO2
![1-Azaspiro[4.4]nonane-7-carboxylic acid chemical structure, C9H15NO2, CAS 1531200-93-7](/s/RWOJZKXZENHKIB-UHFFFAOYSA-N.svg)
1-Azaspiro[4.4]nonane-7-carboxylic acid
CAS 1531200-93-7C9H15NO2
![1-Azaspiro[4.4]nonane hydrochloride chemical structure, C8H16ClN, CAS 1417567-64-6](/s/SVVXIOASDVPOHO-UHFFFAOYSA-N.svg)
1-Azaspiro[4.4]nonane hydrochloride
CAS 1417567-64-6C8H16ClN
![tert-Butyl N-({1-azaspiro[4.4]nonan-7-yl}methyl)carbamate chemical structure, C14H26N2O2, CAS 1781844-52-7](/s/GGFJAHKIDASGNU-UHFFFAOYSA-N.svg)
tert-Butyl N-({1-azaspiro[4.4]nonan-7-yl}methyl)carbamate
CAS 1781844-52-7C14H26N2O2
![tert-Butyl 7-(aminomethyl)-1-azaspiro[4.4]nonane-1-carboxylate chemical structure, C14H26N2O2, CAS 1780408-16-3](/s/IKNSSKAZYPFROF-UHFFFAOYSA-N.svg)
tert-Butyl 7-(aminomethyl)-1-azaspiro[4.4]nonane-1-carboxylate
CAS 1780408-16-3C14H26N2O2
1-Azaspiro(4.4)nonan-4-ol
CAS 1553896-22-2C8H15NO
![1-Methyl-1-azaspiro[4.4]nonan-4-amine chemical structure, C9H18N2, CAS 1545049-23-7](/s/KJRPVWOHXZUSSI-UHFFFAOYSA-N.svg)
1-Methyl-1-azaspiro[4.4]nonan-4-amine
CAS 1545049-23-7C9H18N2
![tert-Butyl 4-amino-1-azaspiro[4.4]nonane-1-carboxylate chemical structure, C13H24N2O2, CAS 1545158-39-1](/s/ZVTWRNPATYORKH-UHFFFAOYSA-N.svg)
tert-Butyl 4-amino-1-azaspiro[4.4]nonane-1-carboxylate
CAS 1545158-39-1C13H24N2O2
![4,4-Difluoro-1-azaspiro[4.4]nonane chemical structure, C8H13F2N, CAS 1557440-97-7](/s/XPNZYCAVSLZBLW-UHFFFAOYSA-N.svg)
4,4-Difluoro-1-azaspiro[4.4]nonane
CAS 1557440-97-7C8H13F2N
![Methyl 1-azaspiro[4.4]nonane-4-carboxylate chemical structure, C10H17NO2, CAS 1784138-14-2](/s/ZUAYKADDWPGGNM-UHFFFAOYSA-N.svg)
Methyl 1-azaspiro[4.4]nonane-4-carboxylate
CAS 1784138-14-2C10H17NO2
![4,4-Difluoro-1-azaspiro[4.4]nonane hydrochloride chemical structure, C8H14ClF2N, CAS 1784334-69-5](/s/PQFFLLAJBYORPW-UHFFFAOYSA-N.svg)
4,4-Difluoro-1-azaspiro[4.4]nonane hydrochloride
CAS 1784334-69-5C8H14ClF2N
![1-Azaspiro[4.4]nonan-3-ol chemical structure, C8H15NO, CAS 1781105-15-4](/s/YKYSATZNGNIOOI-UHFFFAOYSA-N.svg)
1-Azaspiro[4.4]nonan-3-ol
CAS 1781105-15-4C8H15NO
![1-Azaspiro[4.4]nonan-4-ol Hydrochloride chemical structure, C8H16ClNO, CAS 1889398-07-5](/s/CHYVAVKXRLZMPL-UHFFFAOYSA-N.svg)
1-Azaspiro[4.4]nonan-4-ol Hydrochloride
CAS 1889398-07-5C8H16ClNO
![1-Azaspiro[4.4]nonan-3-ol hydrochloride chemical structure, C8H16ClNO, CAS 1889940-05-9](/s/POICLEUMZBMXCZ-UHFFFAOYSA-N.svg)
1-Azaspiro[4.4]nonan-3-ol hydrochloride
CAS 1889940-05-9C8H16ClNO
![3-Fluoro-1-azaspiro[4.4]nonane hydrochloride chemical structure, C8H15ClFN, CAS 1895266-97-3](/s/CSFPQGCTOUBSJC-UHFFFAOYSA-N.svg)
3-Fluoro-1-azaspiro[4.4]nonane hydrochloride
CAS 1895266-97-3C8H15ClFN
![3,3-Difluoro-1-azaspiro[4.4]nonane hydrochloride chemical structure, C8H14ClF2N, CAS 1894832-05-3](/s/YHOOQIAQWPZTLX-UHFFFAOYSA-N.svg)
3,3-Difluoro-1-azaspiro[4.4]nonane hydrochloride
CAS 1894832-05-3C8H14ClF2N
tert-Butyl 4-hydroxy-1-azaspiro(4.4)nonane-1-carboxylate
CAS 1909337-72-9C13H23NO3
- 1-Azaspiro[4.4]nonane-1-carboxylic acid, 7-amino-, 1,1-dimethylethyl ester, (5R,7R)-rel-1251010-58-8C13H24N2O2
- tert-Butyl (5S,8R)-8-amino-1-azaspiro[4.4]nonane-1-carboxylate2165531-68-8C13H24N2O2
- tert-Butyl 7-amino-1-azaspiro[4.4]nonane-1-carboxylate1823269-45-9C13H24N2O2
- tert-Butyl rel-(5S,7R)-7-hydroxy-1-azaspiro[4.4]nonane-1-carboxylate1251011-73-0C13H23NO3
- rac-tert-Butyl (5R,7R)-7-hydroxy-1-azaspiro[4.4]nonane-1-carboxylate1250991-56-0C13H23NO3
- tert-Butyl 7-hydroxy-1-azaspiro[4.4]nonane-1-carboxylate1823268-34-3C13H23NO3
- Ethyl 1-azaspiro[4.4]nonane-4-carboxylate2090595-78-9C11H19NO2
- 1-Azaspiro[4.4]nonane-2-carbonitrile2092023-31-7C9H14N2
- 1-Azaspiro[4.4]nonan-4-amine2007221-63-6C8H16N2
- 1-(tert-Butoxycarbonyl)-1-azaspiro[4.4]nonane-6-carboxylic acid2306277-46-1C14H23NO4
- tert-Butyl 6-amino-1-azaspiro[4.4]nonane-1-carboxylate2306274-94-0C13H24N2O2
- tert-Butyl 6-hydroxy-1-azaspiro[4.4]nonane-1-carboxylate2306270-91-5C13H23NO3
- tert-Butyl (1-azaspiro[4.4]nonan-6-yl)carbamate2306273-22-1C13H24N2O2
- (5R,9R)-1-Azaspiro[4.4]nonan-9-ol, hydrochloride2252434-81-2C8H16ClNO
- 1-Methyl-1-azaspiro[4.4]nonan-3-amine2253639-06-2C9H18N2
- tert-Butyl N-{1-azaspiro[4.4]nonan-3-yl}carbamate2241130-33-4C13H24N2O2
- 1-Azaspiro[4.4]nonane-3-carboxylic acid, hydrochloride2344679-22-5C9H16ClNO2
- 1-Azaspiro[4.4]nonane-3-carboxylic acid2344677-73-0C9H15NO2
- Methyl1-azaspiro[4.4]nonane-3-carboxylatehydrochloride2344680-86-8C10H18ClNO2
- Methyl 1-azaspiro[4.4]nonane-3-carboxylate2344680-85-7C10H17NO2
- 1-[(tert-Butoxy)carbonyl]-1-azaspiro[4.4]nonane-3-carboxylicacid2344684-97-3C14H23NO4
- 3-Methoxy-1-azaspiro[4.4]nonane2580254-67-5C9H17NO
- 1-[(tert-Butoxy)carbonyl]-1-azaspiro[4.4]nonane-4-carboxylic acid2375258-68-5C14H23NO4
- 7-Allyl-1-azaspiro[4.4]nonan-8-ol2406270-52-6C11H19NO
Related scaffolds
Same ring framework with different atoms or bond orders
C1CCC2(C1)CCNC227 chemicals
O=C1NC(=O)C2(CCCC2)N115 chemicals
C1CCC2(C1)OCCO29 chemicals
C1CCC2(C1)CCCC29 chemicals
C1CC2(CCNC2)CN17 chemicals
C1CC2(CN1)OCCO27 chemicals
C1CCC2(C1)CCCO26 chemicals
C1CC2(CCOC2)CN16 chemicals![Scaffold C1CC[N+]2(C1)CCCC2](/scaffold/NZSICTQUKULOSA-UHFFFAOYSA-N/structure.svg)
C1CC[N+]2(C1)CCCC25 chemicals
C1COC2(C1)CCOC24 chemicals
C1CNC2(C1)CCNC24 chemicals
O=C1NC(=O)C2(CCNC2)N14 chemicals