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Murcko scaffold

1,4-Dioxaspiro(4.4)nonane scaffold

179 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
9
Chemicals
179
With full pages
9
Scaffold SMILES

C1CCC2(C1)OCCO2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,4-Dioxaspiro(4.4)nonane page
Murcko scaffold C1CCC2(C1)OCCO2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 179 chemicals

1,4-Dioxaspiro(4.4)nonane-2-methanol, 6-methyl- chemical structure, C9H16O3, CAS 63917-46-4
1,4-Dioxaspiro(4.4)nonane-2-methanol, 6-methyl-
CAS 63917-46-4C9H16O3
1,4-Dioxaspiro(4.4)nonane, 2-butyl- chemical structure, C11H20O2, CAS 78649-62-4
1,4-Dioxaspiro(4.4)nonane, 2-butyl-
CAS 78649-62-4C11H20O2
2,3-Dimethyl-1,4-dioxaspiro[4.4]nonane chemical structure, C9H16O2, CAS 6290-15-9
2,3-Dimethyl-1,4-dioxaspiro[4.4]nonane
CAS 6290-15-9C9H16O2
2-(Chloromethyl)-1,4-dioxaspiro[4.4]nonane chemical structure, C8H13ClO2, CAS 22195-53-5
2-(Chloromethyl)-1,4-dioxaspiro[4.4]nonane
CAS 22195-53-5C8H13ClO2
2-(Ethoxymethyl)-1,4-dioxaspiro[4.4]nonane chemical structure, C10H18O3, CAS 6308-11-8
2-(Ethoxymethyl)-1,4-dioxaspiro[4.4]nonane
CAS 6308-11-8C10H18O3
Methyl 1,4-dioxaspiro[4.4]nonane-7-carboxylate chemical structure, C9H14O4, CAS 90613-04-0
Methyl 1,4-dioxaspiro[4.4]nonane-7-carboxylate
CAS 90613-04-0C9H14O4
Diethyl 1,4-dioxaspiro[4,4]nonan-2,3-dicarboxylate chemical structure, C13H20O6, CAS 6946-61-8
Diethyl 1,4-dioxaspiro[4,4]nonan-2,3-dicarboxylate
CAS 6946-61-8C13H20O6
Ethyl 1,4-dioxaspiro[4.4]nonane-7-carboxylate chemical structure, C10H16O4, CAS 6947-04-2
Ethyl 1,4-dioxaspiro[4.4]nonane-7-carboxylate
CAS 6947-04-2C10H16O4
(9-Methyl-1,4-dioxaspiro[4.4]nonan-9-yl)methanol chemical structure, C9H16O3, CAS 37619-50-4
(9-Methyl-1,4-dioxaspiro[4.4]nonan-9-yl)methanol
CAS 37619-50-4C9H16O3
1,4-Dioxaspiro(4.4)nonane chemical structure, C7H12O2, CAS 176-32-9
1,4-Dioxaspiro(4.4)nonane
CAS 176-32-9C7H12O2
1,4-Dioxaspiro[4.4]non-7-ylmethanol chemical structure, C8H14O3, CAS 65005-20-1
1,4-Dioxaspiro[4.4]non-7-ylmethanol
CAS 65005-20-1C8H14O3
1,4-Dioxaspiro[4.4]nonane, 7,8-bis(hydroxymethyl)- chemical structure, C9H16O4, CAS 1417202-38-0
1,4-Dioxaspiro[4.4]nonane, 7,8-bis(hydroxymethyl)-
CAS 1417202-38-0C9H16O4
N1-(1,4-Dioxaspiro[4.4]nonan-2-ylmethyl)ethane-1,2-diamine chemical structure, C10H20N2O2, CAS 247109-17-7
N1-(1,4-Dioxaspiro[4.4]nonan-2-ylmethyl)ethane-1,2-diamine
CAS 247109-17-7C10H20N2O2
(7R,8S)-8-Amino-1,4-dioxaspiro[4.4]nonane-7-carboxylic acid chemical structure, C8H13NO4, CAS 750567-88-5
(7R,8S)-8-Amino-1,4-dioxaspiro[4.4]nonane-7-carboxylic acid
CAS 750567-88-5C8H13NO4
1,4-Dioxaspiro[4.4]nonane-2,3-dimethanamine, (2R-trans)- chemical structure, C9H18N2O2, CAS 146092-11-7
1,4-Dioxaspiro[4.4]nonane-2,3-dimethanamine, (2R-trans)-
CAS 146092-11-7C9H18N2O2
1-{1,4-Dioxaspiro[4.4]nonan-6-yl}ethan-1-one chemical structure, C9H14O3, CAS 16111-98-1
1-{1,4-Dioxaspiro[4.4]nonan-6-yl}ethan-1-one
CAS 16111-98-1C9H14O3
1,4-Dioxaspiro[4.4]nonan-6-ylmethanol chemical structure, C8H14O3, CAS 23153-74-4
1,4-Dioxaspiro[4.4]nonan-6-ylmethanol
CAS 23153-74-4C8H14O3
trans-8-Amino-1,4-dioxaspiro[4.4]nonan-7-ol chemical structure, C7H13NO3, CAS 170708-38-0
trans-8-Amino-1,4-dioxaspiro[4.4]nonan-7-ol
CAS 170708-38-0C7H13NO3
Ethyl 1,4-dioxaspiro[4.4]nonane-6-carboxylate chemical structure, C10H16O4, CAS 23153-73-3
Ethyl 1,4-dioxaspiro[4.4]nonane-6-carboxylate
CAS 23153-73-3C10H16O4
Methyl 1,4-dioxaspiro[4.4]nonane-6-carboxylate chemical structure, C9H14O4, CAS 110295-58-4
Methyl 1,4-dioxaspiro[4.4]nonane-6-carboxylate
CAS 110295-58-4C9H14O4
[(9S)-1,4-Dioxaspiro[4.4]nonan-9-yl]methyl acetate chemical structure, C10H16O4, CAS 190246-81-2
[(9S)-1,4-Dioxaspiro[4.4]nonan-9-yl]methyl acetate
CAS 190246-81-2C10H16O4
1,4-Dioxaspiro[4.4]nonane-6-propanoicacid chemical structure, C10H16O4, CAS 25188-19-6
1,4-Dioxaspiro[4.4]nonane-6-propanoicacid
CAS 25188-19-6C10H16O4
1,4-Dioxaspiro[4.4]nonan-9-ol chemical structure, C7H12O3, CAS 109459-50-9
1,4-Dioxaspiro[4.4]nonan-9-ol
CAS 109459-50-9C7H12O3
1,4-Dioxaspiro[4.4]nonane, 2,3-dimethyl-, (2R-trans)- chemical structure, C9H16O2, CAS 83461-61-4
1,4-Dioxaspiro[4.4]nonane, 2,3-dimethyl-, (2R-trans)-
CAS 83461-61-4C9H16O2