Murcko scaffold
Spiro(4.4)nonane scaffold
53 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 9
- Chemicals
- 53
- With full pages
- 9
Scaffold SMILES
C1CCC2(C1)CCCC2
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 53 chemicals
Spiro(4.4)nonane
CAS 175-93-9C9H16
![Spiro[4.4]nonan-1-ol chemical structure, C9H16O, CAS 13350-81-7](/s/HQZIAZCARGNEME-UHFFFAOYSA-N.svg)
Spiro[4.4]nonan-1-ol
CAS 13350-81-7C9H16O
![1,1,6,6-Tetramethylspiro[4.4]nonane chemical structure, C13H24, CAS 74054-92-5](/s/DXCGGAAYMYDMBJ-UHFFFAOYSA-N.svg)
1,1,6,6-Tetramethylspiro[4.4]nonane
CAS 74054-92-5C13H24
![Spiro[4.4]nonane-1-carboxylicacid, 4-amino-7-methyl- chemical structure, C11H19NO2, CAS 251461-91-3](/s/MZCYOJRQQYERRW-UHFFFAOYSA-N.svg)
Spiro[4.4]nonane-1-carboxylicacid, 4-amino-7-methyl-
CAS 251461-91-3C11H19NO2
Ndf2mcn7Z8
CAS 21945-23-3C9H16O
![(1S)-Spiro[4.4]nonan-1-ol chemical structure, C9H16O, CAS 21945-22-2](/s/HQZIAZCARGNEME-QMMMGPOBSA-N.svg)
(1S)-Spiro[4.4]nonan-1-ol
CAS 21945-22-2C9H16O
![Spiro[4.4]nonan-1-amine chemical structure, C9H17N, CAS 20440-71-5](/s/OHSZGDISGPXXHR-UHFFFAOYSA-N.svg)
Spiro[4.4]nonan-1-amine
CAS 20440-71-5C9H17N
![Spiro[4.4]nonan-2-ol chemical structure, C9H16O, CAS 99182-61-3](/s/RWVAHZMFOQOBOU-UHFFFAOYSA-N.svg)
Spiro[4.4]nonan-2-ol
CAS 99182-61-3C9H16O
![Spiro[4.4]nonane-2-carboxylic acid chemical structure, C10H16O2, CAS 50599-19-4](/s/GGPRNIGAPJFPJB-UHFFFAOYSA-N.svg)
Spiro[4.4]nonane-2-carboxylic acid
CAS 50599-19-4C10H16O2
![(1S,5S,6S)-6-Aminospiro[4.4]nonan-1-ol chemical structure, C9H17NO, CAS 575342-92-6](/s/RMPOVHNVHWIJIZ-CIUDSAMLSA-N.svg)
(1S,5S,6S)-6-Aminospiro[4.4]nonan-1-ol
CAS 575342-92-6C9H17NO
![(1R,5R,6R)-6-Aminospiro[4.4]nonan-1-ol chemical structure, C9H17NO, CAS 575342-84-6](/s/RMPOVHNVHWIJIZ-IWSPIJDZSA-N.svg)
(1R,5R,6R)-6-Aminospiro[4.4]nonan-1-ol
CAS 575342-84-6C9H17NO
![(1S,6S)-Spiro[4.4]nonane-1,6-diamine chemical structure, C9H18N2, CAS 832747-54-3](/s/BNILUWOCEPQBHS-JVIMKECRSA-N.svg)
(1S,6S)-Spiro[4.4]nonane-1,6-diamine
CAS 832747-54-3C9H18N2
![(1R,6R)-Spiro[4.4]nonane-1,6-diamine chemical structure, C9H18N2, CAS 784181-95-9](/s/BNILUWOCEPQBHS-ZAZKALAHSA-N.svg)
(1R,6R)-Spiro[4.4]nonane-1,6-diamine
CAS 784181-95-9C9H18N2
![{Spiro[4.4]nonan-2-yl}methanol chemical structure, C10H18O, CAS 1147729-16-5](/s/GFNGHJIYETWPAR-UHFFFAOYSA-N.svg)
{Spiro[4.4]nonan-2-yl}methanol
CAS 1147729-16-5C10H18O
![Spiro[4.4]nonane-1,6-diamine chemical structure, C9H18N2, CAS 201405-82-5](/s/BNILUWOCEPQBHS-UHFFFAOYSA-N.svg)
Spiro[4.4]nonane-1,6-diamine
CAS 201405-82-5C9H18N2
![{Spiro[4.4]nonan-1-yl}methanol chemical structure, C10H18O, CAS 24097-45-8](/s/LEOFSZGHTWYFGT-UHFFFAOYSA-N.svg)
{Spiro[4.4]nonan-1-yl}methanol
CAS 24097-45-8C10H18O
![Spiro[4.4]nonane-1-carboxylic acid chemical structure, C10H16O2, CAS 1552140-92-7](/s/DDZKLYHVPRGSNV-UHFFFAOYSA-N.svg)
Spiro[4.4]nonane-1-carboxylic acid
CAS 1552140-92-7C10H16O2
![(1-Hydroxyspiro[4.4]nonan-1-yl)acetic acid chemical structure, C11H18O3, CAS 89789-35-5](/s/VSMZCXODVITSLO-UHFFFAOYSA-N.svg)
(1-Hydroxyspiro[4.4]nonan-1-yl)acetic acid
CAS 89789-35-5C11H18O3
![1-{Spiro[4.4]nonan-1-yl}methanamine chemical structure, C10H19N, CAS 1554224-49-5](/s/DIDUZPQBLNYCMD-UHFFFAOYSA-N.svg)
1-{Spiro[4.4]nonan-1-yl}methanamine
CAS 1554224-49-5C10H19N
![2-{Spiro[4.4]nonan-1-yl}ethan-1-amine chemical structure, C11H21N, CAS 1554317-00-8](/s/DQFKXRQBRAOCMI-UHFFFAOYSA-N.svg)
2-{Spiro[4.4]nonan-1-yl}ethan-1-amine
CAS 1554317-00-8C11H21N
![1-Aminospiro[4.4]nonane-1-carboxylic acid chemical structure, C10H17NO2, CAS 1558110-45-4](/s/VFCZMWIZMJKXBD-UHFFFAOYSA-N.svg)
1-Aminospiro[4.4]nonane-1-carboxylic acid
CAS 1558110-45-4C10H17NO2
![1-(2-Aminoethyl)spiro[4.4]nonan-1-ol chemical structure, C11H21NO, CAS 1552142-07-0](/s/DWWADCXTECEBON-UHFFFAOYSA-N.svg)
1-(2-Aminoethyl)spiro[4.4]nonan-1-ol
CAS 1552142-07-0C11H21NO
![Methyl 1-aminospiro[4.4]nonane-1-carboxylate chemical structure, C11H19NO2, CAS 1544955-87-4](/s/YPVODOVVDHDKFX-UHFFFAOYSA-N.svg)
Methyl 1-aminospiro[4.4]nonane-1-carboxylate
CAS 1544955-87-4C11H19NO2
![Spiro[4.4]nonan-2-amine chemical structure, C9H17N, CAS 1894946-27-0](/s/LKYKLTYURHMHGS-UHFFFAOYSA-N.svg)
Spiro[4.4]nonan-2-amine
CAS 1894946-27-0C9H17N
- 1-{Spiro[4.4]nonan-2-yl}methanamine1895435-55-8C10H19N
- (5S,6S,7R)-7-Amino-6-hydroxyspiro[4.4]nonane-1-carboxylic acid185956-37-0C10H17NO3
- Spiro[4.4]nonane-1-sulfonyl chloride1878780-29-0C9H15ClO2S
- Ethyl 1-aminospiro[4.4]nonane-1-carboxylate1881175-67-2C12H21NO2
- 1-(Chloromethyl)spiro[4.4]nonane1865971-10-3C10H17Cl
- Spiro[4.4]nonane-1-sulfonamide1856775-04-6C9H17NO2S
- Spiro[4.4]nonane-1-thiol1876411-06-1C9H16S
- 1-(Bromomethyl)spiro[4.4]nonane1861231-65-3C10H17Br
- Methyl 2-{1-aminospiro[4.4]nonan-1-yl}acetate1869821-97-5C12H21NO2
- Spiro[4.4]nonane-2-sulfonylchloride2260930-68-3C9H15ClO2S
- 2-Bromospiro[4.4]nonane2247104-07-8C9H15Br
- Spiro[4.4]nonane-2-carbaldehyde2923843-15-4C10H16O
- tert-Butyl N-[(4R,5R,9R)-9-aminospiro[4.4]nonan-4-yl]carbamate1351992-52-3C14H26N2O2
- tert-Butyl N-[(4S,5S,9S)-9-aminospiro[4.4]nonan-4-yl]carbamate1351992-57-8C14H26N2O2
- tert-Butyl 1-aminospiro[4.4]nonane-1-carboxylate2172134-86-8C14H25NO2
- 1-{[(tert-Butoxy)carbonyl]amino}spiro[4.4]nonane-1-carboxylic acid1879861-15-0C15H25NO4
- 2-(1-{[(tert-Butoxy)carbonyl]amino}spiro[4.4]nonan-1-yl)acetic acid2171955-65-8C16H27NO4
- Ethyl 2-{1-aminospiro[4.4]nonan-1-yl}acetate1875789-92-6C13H23NO2
- N-Methylspiro[4.4]nonane-1-sulfonamide2137782-49-9C10H19NO2S
- tert-Butyl 2-{1-aminospiro[4.4]nonan-1-yl}acetate2171819-18-2C15H27NO2
- Spiro[4.4]nonane-1-sulfonyl fluoride2172116-74-2C9H15FO2S
- 1-{Spiro[4.4]nonan-2-yl}methanamine hydrochloride2839138-74-6C10H20ClN
- Spiro[4.4]nonane-2-sulfonamide2580226-35-1C9H17NO2S
- Spiro[4.4]nonane-2-sulfonyl fluoride2648956-44-7C9H15FO2S
Related scaffolds
Same ring framework with different atoms or bond orders
C1CCC2(C1)CCNC227 chemicals
O=C1NC(=O)C2(CCCC2)N115 chemicals
C1CCC2(C1)CCCN213 chemicals
C1CCC2(C1)OCCO29 chemicals
C1CC2(CCNC2)CN17 chemicals
C1CC2(CN1)OCCO27 chemicals
C1CCC2(C1)CCCO26 chemicals
C1CC2(CCOC2)CN16 chemicals![Scaffold C1CC[N+]2(C1)CCCC2](/scaffold/NZSICTQUKULOSA-UHFFFAOYSA-N/structure.svg)
C1CC[N+]2(C1)CCCC25 chemicals
C1COC2(C1)CCOC24 chemicals
C1CNC2(C1)CCNC24 chemicals
O=C1NC(=O)C2(CCNC2)N14 chemicals