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Murcko scaffold

1,4-Dibenzylpiperidine scaffold

54 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
54
With full pages
9
Scaffold SMILES

c1ccc(CC2CCN(Cc3ccccc3)CC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,4-Dibenzylpiperidine page
Murcko scaffold c1ccc(CC2CCN(Cc3ccccc3)CC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 54 chemicals

alpha-Phenyl-1-(phenylmethyl)-4-piperidineacetonitrile chemical structure, C20H22N2, CAS 7254-21-9
alpha-Phenyl-1-(phenylmethyl)-4-piperidineacetonitrile
CAS 7254-21-9C20H22N2
4-Piperidineacetamide, alpha-phenyl-1-(phenylmethyl)- chemical structure, C20H24N2O, CAS 78515-88-5
4-Piperidineacetamide, alpha-phenyl-1-(phenylmethyl)-
CAS 78515-88-5C20H24N2O
4-Piperidineacetic acid, 1-benzyl-4-hydroxy-alpha-phenyl-, methyl ester chemical structure, C21H25NO3, CAS 101997-37-9
4-Piperidineacetic acid, 1-benzyl-4-hydroxy-alpha-phenyl-, methyl ester
CAS 101997-37-9C21H25NO3
4-[(4-Benzylpiperidin-1-yl)methyl]benzoic acid chemical structure, C20H23NO2, CAS 330859-35-3
4-[(4-Benzylpiperidin-1-yl)methyl]benzoic acid
CAS 330859-35-3C20H23NO2
4-Benzyl-1-(2,4-dimethoxybenzyl)piperidine chemical structure, C21H27NO2, CAS 331853-89-5
4-Benzyl-1-(2,4-dimethoxybenzyl)piperidine
CAS 331853-89-5C21H27NO2
Methyl 4-[(4-benzylpiperidin-1-yl)methyl]benzoate chemical structure, C21H25NO2, CAS 359411-52-2
Methyl 4-[(4-benzylpiperidin-1-yl)methyl]benzoate
CAS 359411-52-2C21H25NO2
4-Benzyl-1-(4-nitrobenzyl)piperidine chemical structure, C19H22N2O2, CAS 414886-52-5
4-Benzyl-1-(4-nitrobenzyl)piperidine
CAS 414886-52-5C19H22N2O2
4-Benzyl-1-(3,4-dimethoxybenzyl)piperidine chemical structure, C21H27NO2, CAS 414892-56-1
4-Benzyl-1-(3,4-dimethoxybenzyl)piperidine
CAS 414892-56-1C21H27NO2
4-Benzyl-1-(2-methoxybenzyl)piperidine chemical structure, C20H25NO, CAS 414874-43-4
4-Benzyl-1-(2-methoxybenzyl)piperidine
CAS 414874-43-4C20H25NO
4-Benzyl-1-[(3-methoxyphenyl)methyl]piperidine chemical structure, C20H25NO, CAS 414883-02-6
4-Benzyl-1-[(3-methoxyphenyl)methyl]piperidine
CAS 414883-02-6C20H25NO
4-Benzyl-1-(2-fluorobenzyl)piperidine chemical structure, C19H22FN, CAS 414884-17-6
4-Benzyl-1-(2-fluorobenzyl)piperidine
CAS 414884-17-6C19H22FN
4-Benzyl-1-(4-chlorobenzyl)piperidine chemical structure, C19H22ClN, CAS 414885-76-0
4-Benzyl-1-(4-chlorobenzyl)piperidine
CAS 414885-76-0C19H22ClN
1-((3-Nitrophenyl)methyl)-4-(phenylmethyl)piperidine chemical structure, C19H22N2O2, CAS 414886-04-7
1-((3-Nitrophenyl)methyl)-4-(phenylmethyl)piperidine
CAS 414886-04-7C19H22N2O2
Methyl 3-amino-2-[(4-benzylpiperidino)methyl]benzenecarboxylate chemical structure, C21H26N2O2, CAS 860783-81-9
Methyl 3-amino-2-[(4-benzylpiperidino)methyl]benzenecarboxylate
CAS 860783-81-9C21H26N2O2
Methyl 2-[(4-benzylpiperidino)methyl]-3-nitrobenzenecarboxylate chemical structure, C21H24N2O4, CAS 860644-65-1
Methyl 2-[(4-benzylpiperidino)methyl]-3-nitrobenzenecarboxylate
CAS 860644-65-1C21H24N2O4
2-[(4-Benzylpiperidin-1-yl)methyl]-6-methoxy-4-methylphenol chemical structure, C21H27NO2, CAS 727981-33-1
2-[(4-Benzylpiperidin-1-yl)methyl]-6-methoxy-4-methylphenol
CAS 727981-33-1C21H27NO2
4-[(4-Benzylpiperidin-1-yl)methyl]-N-(2-tert-butylsulfanylethyl)benzamide chemical structure, C26H36N2OS, CAS 688022-05-1
4-[(4-Benzylpiperidin-1-yl)methyl]-N-(2-tert-butylsulfanylethyl)benzamide
CAS 688022-05-1C26H36N2OS
2-(1-Benzylpiperidin-4-yl)-2-phenylpentanedinitrile chemical structure, C23H25N3, CAS 83898-32-2
2-(1-Benzylpiperidin-4-yl)-2-phenylpentanedinitrile
CAS 83898-32-2C23H25N3
1-(1-Benzyl-3-methylpiperidin-4-yl)-1-phenylmethanamine chemical structure, C20H26N2, CAS 101997-50-6
1-(1-Benzyl-3-methylpiperidin-4-yl)-1-phenylmethanamine
CAS 101997-50-6C20H26N2
4-[(4-Benzylpiperidin-1-yl)methyl]-2-ethoxyphenol chemical structure, C21H27NO2, CAS 5261-32-5
4-[(4-Benzylpiperidin-1-yl)methyl]-2-ethoxyphenol
CAS 5261-32-5C21H27NO2
4-Benzyl-1-(2-ethoxybenzyl)piperidine chemical structure, C21H27NO, CAS 414889-17-1
4-Benzyl-1-(2-ethoxybenzyl)piperidine
CAS 414889-17-1C21H27NO
1,4-Dibenzylpiperidin-4-ol chemical structure, C19H23NO, CAS 69635-13-8
1,4-Dibenzylpiperidin-4-ol
CAS 69635-13-8C19H23NO
(2z)-4-[1-Benzyl-4-(4-Chlorobenzyl)piperidin-4-Yl]-2-Hydroxy-4-Oxobut-2-Enoic Acid chemical structure, C23H24ClNO4, CAS 177592-42-6
(2z)-4-[1-Benzyl-4-(4-Chlorobenzyl)piperidin-4-Yl]-2-Hydroxy-4-Oxobut-2-Enoic Acid
CAS 177592-42-6C23H24ClNO4
1-Benzyl-4-(3-fluorobenzyl)piperidine chemical structure, C19H22FN, CAS 771456-84-9
1-Benzyl-4-(3-fluorobenzyl)piperidine
CAS 771456-84-9C19H22FN