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Murcko scaffold

Ring system with 3 rings and 20 atoms

6 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
6
With full pages
3
Scaffold SMILES

O=C(Nc1cccnc1)c1cc(-c2ccccc2)n[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1cccnc1)c1cc(-c2ccccc2)n[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

5-(5-Ethyl-2-hydroxyphenyl)-N-(pyridin-3-yl)-1H-pyrazole-3-carboxamide chemical structure, C17H16N4O2, CAS 879478-47-4
5-(5-Ethyl-2-hydroxyphenyl)-N-(pyridin-3-yl)-1H-pyrazole-3-carboxamide
CAS 879478-47-4C17H16N4O2
3-(2-Hydroxy-5-methylphenyl)-N-pyridin-3-yl-1H-pyrazole-5-carboxamide chemical structure, C16H14N4O2, CAS 879457-40-6
3-(2-Hydroxy-5-methylphenyl)-N-pyridin-3-yl-1H-pyrazole-5-carboxamide
CAS 879457-40-6C16H14N4O2
3-(5-Chloro-2-hydroxyphenyl)-N-(3-pyridinyl)-1H-pyrazole-5-carboxamide chemical structure, C15H11ClN4O2, CAS 879461-88-8
3-(5-Chloro-2-hydroxyphenyl)-N-(3-pyridinyl)-1H-pyrazole-5-carboxamide
CAS 879461-88-8C15H11ClN4O2
3-(3-Chlorophenyl)-N-(6-methoxypyridin-3-yl)-1-methyl-1H-pyrazole-5-carboxamide chemical structure, C17H15ClN4O2, CAS 1374544-18-9
3-(3-Chlorophenyl)-N-(6-methoxypyridin-3-yl)-1-methyl-1H-pyrazole-5-carboxamide
CAS 1374544-18-9C17H15ClN4O2
1-Methyl-3-phenyl-N-(pyridin-3-yl)-1H-pyrazole-5-carboxamide chemical structure, C16H14N4O, CAS 1125885-76-8
1-Methyl-3-phenyl-N-(pyridin-3-yl)-1H-pyrazole-5-carboxamide
CAS 1125885-76-8C16H14N4O
3-(4-Methoxyphenyl)-N-(6-methoxypyridin-3-yl)-1-methyl-1H-pyrazole-5-carboxamide chemical structure, C18H18N4O3, CAS 1630901-03-9
3-(4-Methoxyphenyl)-N-(6-methoxypyridin-3-yl)-1-methyl-1H-pyrazole-5-carboxamide
CAS 1630901-03-9C18H18N4O3