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Murcko scaffold

Ring system with 3 rings and 27 atoms

72 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
27
Chemicals
72
With full pages
3
Scaffold SMILES

O=C(COc1ccccc1)Nc1ccc(S(=O)(=O)Nc2ccccc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(COc1ccccc1)Nc1ccc(S(=O)(=O)Nc2ccccc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 72 chemicals

2-(2,4-Dichlorophenoxy)-N-{4-[(mesitylamino)sulfonyl]phenyl}acetamide chemical structure, C23H22Cl2N2O4S, CAS 431932-65-9
2-(2,4-Dichlorophenoxy)-N-{4-[(mesitylamino)sulfonyl]phenyl}acetamide
CAS 431932-65-9C23H22Cl2N2O4S
2-(4-Chlorophenoxy)-N-{4-[(mesitylamino)sulfonyl]phenyl}acetamide chemical structure, C23H23ClN2O4S, CAS 431995-78-7
2-(4-Chlorophenoxy)-N-{4-[(mesitylamino)sulfonyl]phenyl}acetamide
CAS 431995-78-7C23H23ClN2O4S
N-{4-[(Mesitylamino)sulfonyl]phenyl}-2-(4-methylphenoxy)acetamide chemical structure, C24H26N2O4S, CAS 431934-95-1
N-{4-[(Mesitylamino)sulfonyl]phenyl}-2-(4-methylphenoxy)acetamide
CAS 431934-95-1C24H26N2O4S
N-{4-[(Mesitylamino)sulfonyl]phenyl}-2-(3-methylphenoxy)acetamide chemical structure, C24H26N2O4S, CAS 431941-93-4
N-{4-[(Mesitylamino)sulfonyl]phenyl}-2-(3-methylphenoxy)acetamide
CAS 431941-93-4C24H26N2O4S
N-{4-[(Mesitylamino)sulfonyl]phenyl}-2-(2-methylphenoxy)acetamide chemical structure, C24H26N2O4S, CAS 431985-09-0
N-{4-[(Mesitylamino)sulfonyl]phenyl}-2-(2-methylphenoxy)acetamide
CAS 431985-09-0C24H26N2O4S
2-(4-Chloro-2-methylphenoxy)-N-{4-[(mesitylamino)sulfonyl]phenyl}acetamide chemical structure, C24H25ClN2O4S, CAS 432008-05-4
2-(4-Chloro-2-methylphenoxy)-N-{4-[(mesitylamino)sulfonyl]phenyl}acetamide
CAS 432008-05-4C24H25ClN2O4S
N-[4-[(3,5-Dimethylphenyl)sulfamoyl]phenyl]-2-(2-methoxyphenoxy)acetamide chemical structure, C23H24N2O5S, CAS 433306-36-6
N-[4-[(3,5-Dimethylphenyl)sulfamoyl]phenyl]-2-(2-methoxyphenoxy)acetamide
CAS 433306-36-6C23H24N2O5S
2-(2,4-Dichlorophenoxy)-N-[4-[(4-ethoxyphenyl)sulfamoyl]phenyl]acetamide chemical structure, C22H20Cl2N2O5S, CAS 433313-02-1
2-(2,4-Dichlorophenoxy)-N-[4-[(4-ethoxyphenyl)sulfamoyl]phenyl]acetamide
CAS 433313-02-1C22H20Cl2N2O5S
N-[4-[(4-Ethoxyphenyl)sulfamoyl]phenyl]-2-(2-methoxyphenoxy)acetamide chemical structure, C23H24N2O6S, CAS 433261-25-7
N-[4-[(4-Ethoxyphenyl)sulfamoyl]phenyl]-2-(2-methoxyphenoxy)acetamide
CAS 433261-25-7C23H24N2O6S
N-[4-[(4-Methoxyphenyl)sulfamoyl]phenyl]-2-(4-nitrophenoxy)acetamide chemical structure, C21H19N3O7S, CAS 433965-05-0
N-[4-[(4-Methoxyphenyl)sulfamoyl]phenyl]-2-(4-nitrophenoxy)acetamide
CAS 433965-05-0C21H19N3O7S
2-(4-tert-Butylphenoxy)-N-[4-[(4-fluorophenyl)sulfamoyl]phenyl]acetamide chemical structure, C24H25FN2O4S, CAS 494830-47-6
2-(4-tert-Butylphenoxy)-N-[4-[(4-fluorophenyl)sulfamoyl]phenyl]acetamide
CAS 494830-47-6C24H25FN2O4S
2-(4-Bromo-2-methylphenoxy)-N-[4-[(4-fluorophenyl)sulfamoyl]phenyl]acetamide chemical structure, C21H18BrFN2O4S, CAS 443734-35-8
2-(4-Bromo-2-methylphenoxy)-N-[4-[(4-fluorophenyl)sulfamoyl]phenyl]acetamide
CAS 443734-35-8C21H18BrFN2O4S
2-(2-Chlorophenoxy)-N-[4-[(2,4-dimethylphenyl)sulfamoyl]phenyl]acetamide chemical structure, C22H21ClN2O4S, CAS 497087-29-3
2-(2-Chlorophenoxy)-N-[4-[(2,4-dimethylphenyl)sulfamoyl]phenyl]acetamide
CAS 497087-29-3C22H21ClN2O4S
N-[4-[(3,5-Dimethylphenyl)sulfamoyl]phenyl]-2-(4-methoxyphenoxy)acetamide chemical structure, C23H24N2O5S, CAS 511517-86-5
N-[4-[(3,5-Dimethylphenyl)sulfamoyl]phenyl]-2-(4-methoxyphenoxy)acetamide
CAS 511517-86-5C23H24N2O5S
N-[4-[(4-Ethoxyphenyl)sulfamoyl]phenyl]-2-(4-methoxyphenoxy)acetamide chemical structure, C23H24N2O6S, CAS 497091-56-2
N-[4-[(4-Ethoxyphenyl)sulfamoyl]phenyl]-2-(4-methoxyphenoxy)acetamide
CAS 497091-56-2C23H24N2O6S
2-(4-Chloro-3-methylphenoxy)-N-[4-[(4-ethoxyphenyl)sulfamoyl]phenyl]acetamide chemical structure, C23H23ClN2O5S, CAS 650614-75-8
2-(4-Chloro-3-methylphenoxy)-N-[4-[(4-ethoxyphenyl)sulfamoyl]phenyl]acetamide
CAS 650614-75-8C23H23ClN2O5S
2-(2,4-Dichlorophenoxy)-N-[4-[ethyl(phenyl)sulfamoyl]phenyl]acetamide chemical structure, C22H20Cl2N2O4S, CAS 650575-66-9
2-(2,4-Dichlorophenoxy)-N-[4-[ethyl(phenyl)sulfamoyl]phenyl]acetamide
CAS 650575-66-9C22H20Cl2N2O4S
N-[4-[Ethyl(phenyl)sulfamoyl]phenyl]-2-(2-methylphenoxy)acetamide chemical structure, C23H24N2O4S, CAS 587842-95-3
N-[4-[Ethyl(phenyl)sulfamoyl]phenyl]-2-(2-methylphenoxy)acetamide
CAS 587842-95-3C23H24N2O4S
2-(2,5-Dimethylphenoxy)-N-[4-[ethyl(phenyl)sulfamoyl]phenyl]acetamide chemical structure, C24H26N2O4S, CAS 650575-91-0
2-(2,5-Dimethylphenoxy)-N-[4-[ethyl(phenyl)sulfamoyl]phenyl]acetamide
CAS 650575-91-0C24H26N2O4S
2-(4-Ethylphenoxy)-N-[4-[ethyl(phenyl)sulfamoyl]phenyl]acetamide chemical structure, C24H26N2O4S, CAS 650575-96-5
2-(4-Ethylphenoxy)-N-[4-[ethyl(phenyl)sulfamoyl]phenyl]acetamide
CAS 650575-96-5C24H26N2O4S
2-(4-Chloro-3-methylphenoxy)-N-[4-[ethyl(phenyl)sulfamoyl]phenyl]acetamide chemical structure, C23H23ClN2O4S, CAS 650576-08-2
2-(4-Chloro-3-methylphenoxy)-N-[4-[ethyl(phenyl)sulfamoyl]phenyl]acetamide
CAS 650576-08-2C23H23ClN2O4S
N-[4-[Ethyl(phenyl)sulfamoyl]phenyl]-2-phenoxyacetamide chemical structure, C22H22N2O4S, CAS 650575-63-6
N-[4-[Ethyl(phenyl)sulfamoyl]phenyl]-2-phenoxyacetamide
CAS 650575-63-6C22H22N2O4S
N-[4-[(2,4-Dimethylphenyl)sulfamoyl]phenyl]-2-(2-propan-2-ylphenoxy)acetamide chemical structure, C25H28N2O4S, CAS 650620-50-1
N-[4-[(2,4-Dimethylphenyl)sulfamoyl]phenyl]-2-(2-propan-2-ylphenoxy)acetamide
CAS 650620-50-1C25H28N2O4S
N-[4-[(3,5-Dimethylphenyl)sulfamoyl]phenyl]-2-(2-propan-2-ylphenoxy)acetamide chemical structure, C25H28N2O4S, CAS 650620-53-4
N-[4-[(3,5-Dimethylphenyl)sulfamoyl]phenyl]-2-(2-propan-2-ylphenoxy)acetamide
CAS 650620-53-4C25H28N2O4S