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Murcko scaffold

5-(Phenoxymethyl)-3-pyridin-3-yl-1,2,4-oxadiazole scaffold

31 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
31
With full pages
9
Scaffold SMILES

c1ccc(OCc2nc(-c3cccnc3)no2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5-(Phenoxymethyl)-3-pyridin-3-yl-1,2,4-oxadiazole page
Murcko scaffold c1ccc(OCc2nc(-c3cccnc3)no2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 31 of 31 chemicals

5-[(2,4-Dichlorophenoxy)methyl]-3-pyridin-3-yl-1,2,4-oxadiazole chemical structure, C14H9Cl2N3O2, CAS 421583-91-7
5-[(2,4-Dichlorophenoxy)methyl]-3-pyridin-3-yl-1,2,4-oxadiazole
CAS 421583-91-7C14H9Cl2N3O2
3-{5-[(4-Chloro-3,5-dimethylphenoxy)methyl]-1,2,4-oxadiazol-3-yl}pyridine chemical structure, C16H14ClN3O2, CAS 676485-09-9
3-{5-[(4-Chloro-3,5-dimethylphenoxy)methyl]-1,2,4-oxadiazol-3-yl}pyridine
CAS 676485-09-9C16H14ClN3O2
3-{5-[(2-Bromo-4-methylphenoxy)methyl]-1,2,4-oxadiazol-3-yl}pyridine chemical structure, C15H12BrN3O2, CAS 380874-54-4
3-{5-[(2-Bromo-4-methylphenoxy)methyl]-1,2,4-oxadiazol-3-yl}pyridine
CAS 380874-54-4C15H12BrN3O2
3-{5-[(2-Methoxyphenoxy)methyl]-1,2,4-oxadiazol-3-yl}pyridine chemical structure, C15H13N3O3, CAS 419554-04-4
3-{5-[(2-Methoxyphenoxy)methyl]-1,2,4-oxadiazol-3-yl}pyridine
CAS 419554-04-4C15H13N3O3
5-[2-(4-Chlorophenoxy)propan-2-yl]-3-pyridin-3-yl-1,2,4-oxadiazole chemical structure, C16H14ClN3O2, CAS 690987-78-1
5-[2-(4-Chlorophenoxy)propan-2-yl]-3-pyridin-3-yl-1,2,4-oxadiazole
CAS 690987-78-1C16H14ClN3O2
5-(Phenoxymethyl)-3-pyridin-3-yl-1,2,4-oxadiazole chemical structure, C14H11N3O2, CAS 332922-72-2
5-(Phenoxymethyl)-3-pyridin-3-yl-1,2,4-oxadiazole
CAS 332922-72-2C14H11N3O2
5-[(3,4-Dimethylphenoxy)methyl]-3-pyridin-3-yl-1,2,4-oxadiazole chemical structure, C16H15N3O2, CAS 432499-66-6
5-[(3,4-Dimethylphenoxy)methyl]-3-pyridin-3-yl-1,2,4-oxadiazole
CAS 432499-66-6C16H15N3O2
3-{5-[(4-Chlorophenoxy)methyl]-1,2,4-oxadiazol-3-yl}pyridine chemical structure, C14H10ClN3O2, CAS 27390-29-0
3-{5-[(4-Chlorophenoxy)methyl]-1,2,4-oxadiazol-3-yl}pyridine
CAS 27390-29-0C14H10ClN3O2
3-(5-{[4-(Propan-2-yl)phenoxy]methyl}-1,2,4-oxadiazol-3-yl)pyridine chemical structure, C17H17N3O2, CAS 432536-93-1
3-(5-{[4-(Propan-2-yl)phenoxy]methyl}-1,2,4-oxadiazol-3-yl)pyridine
CAS 432536-93-1C17H17N3O2
5-[(4-Ethylphenoxy)methyl]-3-pyridin-3-yl-1,2,4-oxadiazole chemical structure, C16H15N3O2, CAS 432006-57-0
5-[(4-Ethylphenoxy)methyl]-3-pyridin-3-yl-1,2,4-oxadiazole
CAS 432006-57-0C16H15N3O2
3-{5-[(4-Chloro-2-methylphenoxy)methyl]-1,2,4-oxadiazol-3-yl}pyridine chemical structure, C15H12ClN3O2, CAS 380163-80-4
3-{5-[(4-Chloro-2-methylphenoxy)methyl]-1,2,4-oxadiazol-3-yl}pyridine
CAS 380163-80-4C15H12ClN3O2
5-[(2,4-Dimethylphenoxy)methyl]-3-pyridin-3-yl-1,2,4-oxadiazole chemical structure, C16H15N3O2, CAS 370849-19-7
5-[(2,4-Dimethylphenoxy)methyl]-3-pyridin-3-yl-1,2,4-oxadiazole
CAS 370849-19-7C16H15N3O2
3-{5-[(4-Methoxyphenoxy)methyl]-1,2,4-oxadiazol-3-yl}pyridine chemical structure, C15H13N3O3, CAS 419554-22-6
3-{5-[(4-Methoxyphenoxy)methyl]-1,2,4-oxadiazol-3-yl}pyridine
CAS 419554-22-6C15H13N3O3
3-{5-[(4-Bromo-3-methylphenoxy)methyl]-1,2,4-oxadiazol-3-yl}pyridine chemical structure, C15H12BrN3O2, CAS 442649-27-6
3-{5-[(4-Bromo-3-methylphenoxy)methyl]-1,2,4-oxadiazol-3-yl}pyridine
CAS 442649-27-6C15H12BrN3O2
3-{5-[(3-Methylphenoxy)methyl]-1,2,4-oxadiazol-3-yl}pyridine chemical structure, C15H13N3O2, CAS 384376-67-4
3-{5-[(3-Methylphenoxy)methyl]-1,2,4-oxadiazol-3-yl}pyridine
CAS 384376-67-4C15H13N3O2
5-[(2,5-Dimethylphenoxy)methyl]-3-pyridin-3-yl-1,2,4-oxadiazole chemical structure, C16H15N3O2, CAS 421575-59-9
5-[(2,5-Dimethylphenoxy)methyl]-3-pyridin-3-yl-1,2,4-oxadiazole
CAS 421575-59-9C16H15N3O2
RefChem:381428 chemical structure, C16H15N3O2, CAS 5690-53-9
RefChem:381428
CAS 5690-53-9C16H15N3O2
5-[(2-Chlorophenoxy)methyl]-3-pyridin-3-yl-1,2,4-oxadiazole chemical structure, C14H10ClN3O2, CAS 351976-26-6
5-[(2-Chlorophenoxy)methyl]-3-pyridin-3-yl-1,2,4-oxadiazole
CAS 351976-26-6C14H10ClN3O2
3-{5-[(2-Methylphenoxy)methyl]-1,2,4-oxadiazol-3-yl}pyridine chemical structure, C15H13N3O2, CAS 421581-78-4
3-{5-[(2-Methylphenoxy)methyl]-1,2,4-oxadiazol-3-yl}pyridine
CAS 421581-78-4C15H13N3O2
3-{5-[(4-Bromophenoxy)methyl]-1,2,4-oxadiazol-3-yl}pyridine chemical structure, C14H10BrN3O2, CAS 568559-13-7
3-{5-[(4-Bromophenoxy)methyl]-1,2,4-oxadiazol-3-yl}pyridine
CAS 568559-13-7C14H10BrN3O2
3-{5-[(4-Chloro-3-methylphenoxy)methyl]-1,2,4-oxadiazol-3-yl}pyridine chemical structure, C15H12ClN3O2, CAS 421584-05-6
3-{5-[(4-Chloro-3-methylphenoxy)methyl]-1,2,4-oxadiazol-3-yl}pyridine
CAS 421584-05-6C15H12ClN3O2
3-{5-[(2,3,5-Trimethylphenoxy)methyl]-1,2,4-oxadiazol-3-yl}pyridine chemical structure, C17H17N3O2, CAS 519035-97-3
3-{5-[(2,3,5-Trimethylphenoxy)methyl]-1,2,4-oxadiazol-3-yl}pyridine
CAS 519035-97-3C17H17N3O2
3-(2-Methoxy-6-methylpyridin-3-yl)-5-(phenoxymethyl)-1,2,4-oxadiazole chemical structure, C16H15N3O3, CAS 701932-59-4
3-(2-Methoxy-6-methylpyridin-3-yl)-5-(phenoxymethyl)-1,2,4-oxadiazole
CAS 701932-59-4C16H15N3O3
3-{5-[(4-Bromo-3,5-dimethylphenoxy)methyl]-1,2,4-oxadiazol-3-yl}pyridine chemical structure, C16H14BrN3O2, CAS 434303-59-0
3-{5-[(4-Bromo-3,5-dimethylphenoxy)methyl]-1,2,4-oxadiazol-3-yl}pyridine
CAS 434303-59-0C16H14BrN3O2