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Murcko scaffold

Ring system with 3 rings and 21 atoms

16 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 21
Chemicals: 16
With full pages: 3

Scaffold SMILES

O=c1cc[nH]c2ccc(S(=O)(=O)Nc3ccccc3)cc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=c1cc[nH]c2ccc(S(=O)(=O)Nc3ccccc3)cc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

6-{[(4-Fluorophenyl)(methyl)amino]sulfonyl}-4-oxo-1,4-dihydroquinoline-3-carboxylic acid chemical structure, C17H13FN2O5S, CAS 434907-99-0

6-{[(4-Fluorophenyl)(methyl)amino]sulfonyl}-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

CAS 434907-99-0C₁₇H₁₃FN₂O₅S

N-Butyl-N-ethyl-6-[[(4-ethylphenyl)methylamino]sulfonyl]-1,4-dihydro-4-oxo-3-quinolinecarboxamide chemical structure, C25H31N3O4S, CAS 422558-21-2

N-Butyl-N-ethyl-6-[[(4-ethylphenyl)methylamino]sulfonyl]-1,4-dihydro-4-oxo-3-quinolinecarboxamide

CAS 422558-21-2C₂₅H₃₁N₃O₄S

N-Butyl-6-[[Ethyl(3-methylphenyl)amino]sulfonyl]-1,4-dihydro-N-methyl-4-oxo-3-quinolinecarboxamide chemical structure, C24H29N3O4S, CAS 422540-80-5

N-Butyl-6-[[Ethyl(3-methylphenyl)amino]sulfonyl]-1,4-dihydro-N-methyl-4-oxo-3-quinolinecarboxamide

CAS 422540-80-5C₂₄H₂₉N₃O₄S

N-Butyl-N-ethyl-6-(N-(4-isopropylphenyl)-N-methylsulfamoyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide chemical structure, C26H33N3O4S, CAS 434920-34-0

N-Butyl-N-ethyl-6-(N-(4-isopropylphenyl)-N-methylsulfamoyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide

CAS 434920-34-0C₂₆H₃₃N₃O₄S

6-(N-(4-Bromophenyl)-N-methylsulfamoyl)-N-butyl-N-ethyl-4-oxo-1,4-dihydroquinoline-3-carboxamide chemical structure, C23H26BrN3O4S, CAS 434921-27-4

6-(N-(4-Bromophenyl)-N-methylsulfamoyl)-N-butyl-N-ethyl-4-oxo-1,4-dihydroquinoline-3-carboxamide

CAS 434921-27-4C₂₃H₂₆BrN₃O₄S

N-Butyl-6-[[(2-Ethylphenyl)methylamino]sulfonyl]-1,4-dihydro-N-methyl-4-oxo-3-quinolinecarboxamide chemical structure, C24H29N3O4S, CAS 434918-79-3

N-Butyl-6-[[(2-Ethylphenyl)methylamino]sulfonyl]-1,4-dihydro-N-methyl-4-oxo-3-quinolinecarboxamide

CAS 434918-79-3C₂₄H₂₉N₃O₄S

6-{[(4-Ethylphenyl)(methyl)amino]sulfonyl}-4-oxo-1,4-dihydroquinoline-3-carboxylic acid chemical structure, C19H18N2O5S, CAS 434907-95-6

6-{[(4-Ethylphenyl)(methyl)amino]sulfonyl}-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

CAS 434907-95-6C₁₉H₁₈N₂O₅S

6-{[(3,4-Dimethylphenyl)(methyl)amino]sulfonyl}-4-oxo-1,4-dihydroquinoline-3-carboxylic acid chemical structure, C19H18N2O5S, CAS 434907-98-9

6-{[(3,4-Dimethylphenyl)(methyl)amino]sulfonyl}-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

CAS 434907-98-9C₁₉H₁₈N₂O₅S

6-[[Ethyl(4-fluorophenyl)amino]sulfonyl]-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid chemical structure, C18H15FN2O5S, CAS 434908-01-7

6-[[Ethyl(4-fluorophenyl)amino]sulfonyl]-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid

CAS 434908-01-7C₁₈H₁₅FN₂O₅S

N,N-Diethyl-6-[[(4-fluorophenyl)methylamino]sulfonyl]-1,4-dihydro-4-oxo-3-quinolinecarboxamide chemical structure, C21H22FN3O4S, CAS 423127-44-0

N,N-Diethyl-6-[[(4-fluorophenyl)methylamino]sulfonyl]-1,4-dihydro-4-oxo-3-quinolinecarboxamide

CAS 423127-44-0C₂₁H₂₂FN₃O₄S

N-Butyl-6-(N-(4-ethoxyphenyl)-N-methylsulfamoyl)-N-ethyl-4-oxo-1,4-dihydroquinoline-3-carboxamide chemical structure, C25H31N3O5S, CAS 434919-33-2

N-Butyl-6-(N-(4-ethoxyphenyl)-N-methylsulfamoyl)-N-ethyl-4-oxo-1,4-dihydroquinoline-3-carboxamide

CAS 434919-33-2C₂₅H₃₁N₃O₅S

6-[[(4-Fluorophenyl)methylamino]sulfonyl]-1,4-dihydro-4-oxo-N,N-dipropyl-3-quinolinecarboxamide chemical structure, C23H26FN3O4S, CAS 422560-31-4

6-[[(4-Fluorophenyl)methylamino]sulfonyl]-1,4-dihydro-4-oxo-N,N-dipropyl-3-quinolinecarboxamide

CAS 422560-31-4C₂₃H₂₆FN₃O₄S

N-Butyl-6-[[(4-chloro-2-fluorophenyl)methylamino]sulfonyl]-N-ethyl-1,4-dihydro-4-oxo-3-quinolinecarboxamide chemical structure, C23H25ClFN3O4S, CAS 422553-05-7

N-Butyl-6-[[(4-chloro-2-fluorophenyl)methylamino]sulfonyl]-N-ethyl-1,4-dihydro-4-oxo-3-quinolinecarboxamide

CAS 422553-05-7C₂₃H₂₅ClFN₃O₄S

N-Butyl-6-(N-(4-chlorophenyl)-N-methylsulfamoyl)-N-ethyl-4-oxo-1,4-dihydroquinoline-3-carboxamide chemical structure, C23H26ClN3O4S, CAS 422559-26-0

N-Butyl-6-(N-(4-chlorophenyl)-N-methylsulfamoyl)-N-ethyl-4-oxo-1,4-dihydroquinoline-3-carboxamide

CAS 422559-26-0C₂₃H₂₆ClN₃O₄S

N-Hexyl-6-[methyl-(4-propan-2-ylphenyl)sulfamoyl]-4-oxo-1H-quinoline-3-carboxamide chemical structure, C26H33N3O4S, CAS 6801-48-5

N-Hexyl-6-[methyl-(4-propan-2-ylphenyl)sulfamoyl]-4-oxo-1H-quinoline-3-carboxamide

CAS 6801-48-5C₂₆H₃₃N₃O₄S

N-(2,2-Dimethoxyethyl)-6-[methyl(2-methylphenyl)sulfamoyl]-4-oxo-1,4-dihydroquinoline-3-carboxamide chemical structure, C22H25N3O6S, CAS 6801-62-3

N-(2,2-Dimethoxyethyl)-6-[methyl(2-methylphenyl)sulfamoyl]-4-oxo-1,4-dihydroquinoline-3-carboxamide

CAS 6801-62-3C₂₂H₂₅N₃O₆S