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Murcko scaffold

Ring system with 3 rings and 17 atoms

133 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
133
With full pages
14
Scaffold SMILES

C(=Cc1nc2ccccc2s1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C(=Cc1nc2ccccc2s1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 133 chemicals

2-{2-[4-(Dimethylamino)phenyl]ethenyl}-3-methyl-1,3-benzothiazol-3-ium iodide chemical structure, C18H19IN2S
2-{2-[4-(Dimethylamino)phenyl]ethenyl}-3-methyl-1,3-benzothiazol-3-ium iodide
C18H19IN2S
2-[4-(Dimethylamino)styryl]-3-methyl-3-benzothiazolium chemical structure, C18H19N2S+, CAS 16197-32-3
2-[4-(Dimethylamino)styryl]-3-methyl-3-benzothiazolium
CAS 16197-32-3C18H19N2S+
Benzothiazole, 2-[2-(4-methoxyphenyl)ethenyl]- chemical structure, C16H13NOS, CAS 59198-05-9
Benzothiazole, 2-[2-(4-methoxyphenyl)ethenyl]-
CAS 59198-05-9C16H13NOS
2-(1,3-Benzothiazol-2-yl)-3-phenylprop-2-enenitrile chemical structure, C16H10N2S, CAS 85460-26-0
2-(1,3-Benzothiazol-2-yl)-3-phenylprop-2-enenitrile
CAS 85460-26-0C16H10N2S
2-(1,3-Benzothiazol-2-yl)-3-(3-fluorophenyl)-3-hydroxyacrylonitrile chemical structure, C16H9FN2OS, CAS 324544-31-2
2-(1,3-Benzothiazol-2-yl)-3-(3-fluorophenyl)-3-hydroxyacrylonitrile
CAS 324544-31-2C16H9FN2OS
(Z)-2-(Benzo[d]thiazol-2-yl)-3-(4-bromophenyl)-3-hydroxyacrylonitrile chemical structure, C16H9BrN2OS, CAS 304897-04-9
(Z)-2-(Benzo[d]thiazol-2-yl)-3-(4-bromophenyl)-3-hydroxyacrylonitrile
CAS 304897-04-9C16H9BrN2OS
2-Benzothiazol-2-yl-3-hydroxy-3-(4-iodo-phenyl)-acrylonitrile chemical structure, C16H9IN2OS, CAS 304897-06-1
2-Benzothiazol-2-yl-3-hydroxy-3-(4-iodo-phenyl)-acrylonitrile
CAS 304897-06-1C16H9IN2OS
(Z)-2-(Benzo[d]thiazol-2-yl)-3-hydroxy-3-(4-methoxyphenyl)acrylonitrile chemical structure, C17H12N2O2S, CAS 301312-82-3
(Z)-2-(Benzo[d]thiazol-2-yl)-3-hydroxy-3-(4-methoxyphenyl)acrylonitrile
CAS 301312-82-3C17H12N2O2S
4-[2-(1,3-Benzothiazol-2-yl)ethenyl]-N,N-diethylaniline chemical structure, C19H20N2S, CAS 13242-17-6
4-[2-(1,3-Benzothiazol-2-yl)ethenyl]-N,N-diethylaniline
CAS 13242-17-6C19H20N2S
Benzothiazole, 2-[2-(4-chlorophenyl)ethenyl]- chemical structure, C15H10ClNS, CAS 30216-38-7
Benzothiazole, 2-[2-(4-chlorophenyl)ethenyl]-
CAS 30216-38-7C15H10ClNS
(E)-(3,5-Dichlorobenzoyl)(2,3-dihydro-1,3-benzothiazol-2-ylidene)acetonitrile chemical structure, C16H8Cl2N2OS
(E)-(3,5-Dichlorobenzoyl)(2,3-dihydro-1,3-benzothiazol-2-ylidene)acetonitrile
C16H8Cl2N2OS
2-(1,3-Benzothiazol-2-yl)-3-hydroxy-3-(4-methoxyphenyl)prop-2-enenitrile chemical structure, C17H12N2O2S
2-(1,3-Benzothiazol-2-yl)-3-hydroxy-3-(4-methoxyphenyl)prop-2-enenitrile
C17H12N2O2S
2-(1,3-Benzothiazol-2-yl)-3-(3-bromophenyl)-3-hydroxyprop-2-enenitrile chemical structure, C16H9BrN2OS
2-(1,3-Benzothiazol-2-yl)-3-(3-bromophenyl)-3-hydroxyprop-2-enenitrile
C16H9BrN2OS
2-(1,3-Benzothiazol-2-yl)-3-(4-chloro-3-nitrophenyl)-3-hydroxyprop-2-enenitrile chemical structure, C16H8ClN3O3S, CAS 305372-43-4
2-(1,3-Benzothiazol-2-yl)-3-(4-chloro-3-nitrophenyl)-3-hydroxyprop-2-enenitrile
CAS 305372-43-4C16H8ClN3O3S
Benzenamine, N,N-dimethyl-4-[2-(5-nitro-2-benzothiazolyl)ethenyl]- chemical structure, C17H15N3O2S, CAS 647036-19-9
Benzenamine, N,N-dimethyl-4-[2-(5-nitro-2-benzothiazolyl)ethenyl]-
CAS 647036-19-9C17H15N3O2S
4-[2-(1,3-Benzothiazol-2-yl)-2-cyano-1-hydroxyethenyl]-N,N-bis(prop-2-enyl)benzenesulfonamide chemical structure, C22H19N3O3S2
4-[2-(1,3-Benzothiazol-2-yl)-2-cyano-1-hydroxyethenyl]-N,N-bis(prop-2-enyl)benzenesulfonamide
C22H19N3O3S2
2-(4-(Dimethylamino)styryl)-3-ethylbenzo[d]thiazol-3-ium chemical structure, C19H21N2S+, CAS 41017-17-8
2-(4-(Dimethylamino)styryl)-3-ethylbenzo[d]thiazol-3-ium
CAS 41017-17-8C19H21N2S+
2-[2-(2,4-Dimethoxyphenyl)ethenyl]-1,3-benzothiazole chemical structure, C17H15NO2S, CAS 923030-43-7
2-[2-(2,4-Dimethoxyphenyl)ethenyl]-1,3-benzothiazole
CAS 923030-43-7C17H15NO2S
4-[2-(1,3-Benzothiazol-2-yl)-2-cyano-1-hydroxyethenyl]benzonitrile chemical structure, C17H9N3OS
4-[2-(1,3-Benzothiazol-2-yl)-2-cyano-1-hydroxyethenyl]benzonitrile
C17H9N3OS
2-(1,3-Benzothiazol-2-yl)-3-[2-(2-chloro-2-cyanoethyl)phenyl]-3-hydroxyprop-2-enenitrile chemical structure, C19H12ClN3OS
2-(1,3-Benzothiazol-2-yl)-3-[2-(2-chloro-2-cyanoethyl)phenyl]-3-hydroxyprop-2-enenitrile
C19H12ClN3OS
(2E)-2-(1,3-Benzothiazol-2-yl)-3-(3,4-dimethoxyphenyl)prop-2-enenitrile chemical structure, C18H14N2O2S, CAS 912288-44-9
(2E)-2-(1,3-Benzothiazol-2-yl)-3-(3,4-dimethoxyphenyl)prop-2-enenitrile
CAS 912288-44-9C18H14N2O2S
(2E)-2-(1,3-Benzothiazol-2-yl)-3-(2,5-dimethoxyphenyl)prop-2-enenitrile chemical structure, C18H14N2O2S, CAS 333434-87-0
(2E)-2-(1,3-Benzothiazol-2-yl)-3-(2,5-dimethoxyphenyl)prop-2-enenitrile
CAS 333434-87-0C18H14N2O2S
(2E)-2-(1,3-Benzothiazol-2-yl)-3-(3-methoxyphenyl)prop-2-enenitrile chemical structure, C17H12N2OS, CAS 1638294-92-4
(2E)-2-(1,3-Benzothiazol-2-yl)-3-(3-methoxyphenyl)prop-2-enenitrile
CAS 1638294-92-4C17H12N2OS
(2E)-2-(1,3-Benzothiazol-2-yl)-3-(2,6-dichlorophenyl)prop-2-enenitrile chemical structure, C16H8Cl2N2S, CAS 112632-92-5
(2E)-2-(1,3-Benzothiazol-2-yl)-3-(2,6-dichlorophenyl)prop-2-enenitrile
CAS 112632-92-5C16H8Cl2N2S