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Murcko scaffold

Pyrazolo(1,5-a)pyrimidine scaffold

2,195 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
9
Chemicals
2,195
With full pages
244
Scaffold SMILES

c1cnc2ccnn2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Pyrazolo(1,5-a)pyrimidine page
Murcko scaffold c1cnc2ccnn2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1,105 to 1,152 of 2,195 chemicals

5,7-Dichloro-2-ethylpyrazolo[1,5-a]pyrimidine chemical structure, C8H7Cl2N3, CAS 1296225-10-9
5,7-Dichloro-2-ethylpyrazolo[1,5-a]pyrimidine
CAS 1296225-10-9C8H7Cl2N3
5,7-Dichloro-2-isopropylpyrazolo[1,5-A]pyrimidine chemical structure, C9H9Cl2N3, CAS 1211591-34-2
5,7-Dichloro-2-isopropylpyrazolo[1,5-A]pyrimidine
CAS 1211591-34-2C9H9Cl2N3
2-(Pyrazolo[1,5-a]pyrimidin-5-yloxy)acetic acid chemical structure, C8H7N3O3, CAS 1593993-39-5
2-(Pyrazolo[1,5-a]pyrimidin-5-yloxy)acetic acid
CAS 1593993-39-5C8H7N3O3
6-Bromo-3-iodo-2-methylpyrazolo[1,5-a]pyrimidine chemical structure, C7H5BrIN3, CAS 1600378-80-0
6-Bromo-3-iodo-2-methylpyrazolo[1,5-a]pyrimidine
CAS 1600378-80-0C7H5BrIN3
3-Cyano-5-methylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid chemical structure, C9H6N4O2, CAS 1592568-05-2
3-Cyano-5-methylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid
CAS 1592568-05-2C9H6N4O2
7-Chloro-6-ethyl-5-methylpyrazolo[1,5-a]pyrimidine-3-carbonitrile chemical structure, C10H9ClN4, CAS 1598492-76-2
7-Chloro-6-ethyl-5-methylpyrazolo[1,5-a]pyrimidine-3-carbonitrile
CAS 1598492-76-2C10H9ClN4
7-Chloro-5-propylpyrazolo[1,5-a]pyrimidine-3-carbonitrile chemical structure, C10H9ClN4, CAS 1599396-31-2
7-Chloro-5-propylpyrazolo[1,5-a]pyrimidine-3-carbonitrile
CAS 1599396-31-2C10H9ClN4
Ethyl 7-chloro-5-methylpyrazolo[1,5-A]pyrimidine-2-carboxylate chemical structure, C10H10ClN3O2, CAS 115735-34-7
Ethyl 7-chloro-5-methylpyrazolo[1,5-A]pyrimidine-2-carboxylate
CAS 115735-34-7C10H10ClN3O2
Ethyl 7-chloro-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylate chemical structure, C10H7ClF3N3O2, CAS 1712732-41-6
Ethyl 7-chloro-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS 1712732-41-6C10H7ClF3N3O2
5,7-Dichloropyrazolo[1,5-a]pyrimidine-2-carboxylic acid chemical structure, C7H3Cl2N3O2, CAS 1592302-01-6
5,7-Dichloropyrazolo[1,5-a]pyrimidine-2-carboxylic acid
CAS 1592302-01-6C7H3Cl2N3O2
5,7-Dichloro-3-iodo-2-methyl-pyrazolo[1,5-a]pyrimidine chemical structure, C7H4Cl2IN3, CAS 1601808-18-7
5,7-Dichloro-3-iodo-2-methyl-pyrazolo[1,5-a]pyrimidine
CAS 1601808-18-7C7H4Cl2IN3
7-Chloro-3-iodo-2,5-dimethylpyrazolo[1,5-a]pyrimidine chemical structure, C8H7ClIN3, CAS 1592357-94-2
7-Chloro-3-iodo-2,5-dimethylpyrazolo[1,5-a]pyrimidine
CAS 1592357-94-2C8H7ClIN3
5-tert-Butyl-7-chloro-3-iodo-2-methylpyrazolo[1,5-a]pyrimidine chemical structure, C11H13ClIN3, CAS 1601082-06-7
5-tert-Butyl-7-chloro-3-iodo-2-methylpyrazolo[1,5-a]pyrimidine
CAS 1601082-06-7C11H13ClIN3
3-Fluoropyrazolo[1,5-a]pyrimidine-6-carboxylic acid chemical structure, C7H4FN3O2, CAS 1895243-12-5
3-Fluoropyrazolo[1,5-a]pyrimidine-6-carboxylic acid
CAS 1895243-12-5C7H4FN3O2
3-Fluoro-7-methylpyrazolo[1,5-a]pyrimidine-5-carboxylic acid chemical structure, C8H6FN3O2, CAS 1352397-88-6
3-Fluoro-7-methylpyrazolo[1,5-a]pyrimidine-5-carboxylic acid
CAS 1352397-88-6C8H6FN3O2
6-Amino-2-ethylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid chemical structure, C9H10N4O2, CAS 1888790-39-3
6-Amino-2-ethylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid
CAS 1888790-39-3C9H10N4O2
N-(2-Aminoethyl)-N-methylpyrazolo[1,5-a]pyrimidin-5-amine chemical structure, C9H13N5, CAS 1545262-56-3
N-(2-Aminoethyl)-N-methylpyrazolo[1,5-a]pyrimidin-5-amine
CAS 1545262-56-3C9H13N5
Methyl(2-{pyrazolo[1,5-a]pyrimidin-5-yloxy}ethyl)amine chemical structure, C9H12N4O, CAS 1551799-43-9
Methyl(2-{pyrazolo[1,5-a]pyrimidin-5-yloxy}ethyl)amine
CAS 1551799-43-9C9H12N4O
2-{Pyrazolo[1,5-a]pyrimidin-5-yloxy}ethan-1-amine chemical structure, C8H10N4O, CAS 1545342-70-8
2-{Pyrazolo[1,5-a]pyrimidin-5-yloxy}ethan-1-amine
CAS 1545342-70-8C8H10N4O
3-Cyano-5-methylpyrazolo[1,5-a]pyrimidine-7-carboxylic acid chemical structure, C9H6N4O2, CAS 1595567-77-3
3-Cyano-5-methylpyrazolo[1,5-a]pyrimidine-7-carboxylic acid
CAS 1595567-77-3C9H6N4O2
(7-Aminopyrazolo[1,5-a]pyrimidin-3-yl)methanol chemical structure, C7H8N4O, CAS 1892810-45-5
(7-Aminopyrazolo[1,5-a]pyrimidin-3-yl)methanol
CAS 1892810-45-5C7H8N4O
2-Methoxypyrazolo[1,5-a]pyrimidine-3-carboxylic acid chemical structure, C8H7N3O3, CAS 1897011-12-9
2-Methoxypyrazolo[1,5-a]pyrimidine-3-carboxylic acid
CAS 1897011-12-9C8H7N3O3
5-Methylpyrazolo[1,5-a]pyrimidin-2-amine chemical structure, C7H8N4, CAS 2137721-53-8
5-Methylpyrazolo[1,5-a]pyrimidin-2-amine
CAS 2137721-53-8C7H8N4
3-Bromo-7-methoxy-5-methyl-6-(propan-2-yl)pyrazolo[1,5-a]pyrimidine chemical structure, C11H14BrN3O, CAS 1668629-93-3
3-Bromo-7-methoxy-5-methyl-6-(propan-2-yl)pyrazolo[1,5-a]pyrimidine
CAS 1668629-93-3C11H14BrN3O