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Murcko scaffold

Pyrazolo(1,5-a)pyrimidine scaffold

2,195 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
9
Chemicals
2,195
With full pages
244
Scaffold SMILES

c1cnc2ccnn2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Pyrazolo(1,5-a)pyrimidine page
Murcko scaffold c1cnc2ccnn2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1,153 to 1,200 of 2,195 chemicals

5-(Difluoromethyl)-3-nitropyrazolo[1,5-A]pyrimidine chemical structure, C7H4F2N4O2, CAS 1823818-09-2
5-(Difluoromethyl)-3-nitropyrazolo[1,5-A]pyrimidine
CAS 1823818-09-2C7H4F2N4O2
Methyl 5-(difluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylate chemical structure, C9H7F2N3O2, CAS 1855891-61-0
Methyl 5-(difluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS 1855891-61-0C9H7F2N3O2
2-{3-Chloropyrazolo[1,5-a]pyrimidin-6-yl}ethan-1-amine chemical structure, C8H9ClN4, CAS 1820619-63-3
2-{3-Chloropyrazolo[1,5-a]pyrimidin-6-yl}ethan-1-amine
CAS 1820619-63-3C8H9ClN4
7-Bromo-3-iodopyrazolo[1,5-a]pyrimidine chemical structure, C6H3BrIN3, CAS 2383001-09-8
7-Bromo-3-iodopyrazolo[1,5-a]pyrimidine
CAS 2383001-09-8C6H3BrIN3
3,7-Dibromopyrazolo[1,5-a]pyrimidine chemical structure, C6H3Br2N3, CAS 2375204-82-1
3,7-Dibromopyrazolo[1,5-a]pyrimidine
CAS 2375204-82-1C6H3Br2N3
7-Bromo-3-chloropyrazolo(1,5-a)pyrimidine chemical structure, C6H3BrClN3, CAS 2092491-46-6
7-Bromo-3-chloropyrazolo(1,5-a)pyrimidine
CAS 2092491-46-6C6H3BrClN3
5-Aminopyrazolo[1,5-a]pyrimidine-3-carbonitrile chemical structure, C7H5N5, CAS 1610021-96-9
5-Aminopyrazolo[1,5-a]pyrimidine-3-carbonitrile
CAS 1610021-96-9C7H5N5
N-(2,3,6-Trimethylpyrazolo[1,5-a]pyrimidin-7-yl)acetamide chemical structure, C11H14N4O, CAS 1210-40-8
N-(2,3,6-Trimethylpyrazolo[1,5-a]pyrimidin-7-yl)acetamide
CAS 1210-40-8C11H14N4O
5-Methoxypyrazolo[1,5-a]pyrimidine-3-carboxylic acid chemical structure, C8H7N3O3, CAS 1823951-60-5
5-Methoxypyrazolo[1,5-a]pyrimidine-3-carboxylic acid
CAS 1823951-60-5C8H7N3O3
Methyl 6-amino-2-ethylpyrazolo[1,5-a]pyrimidine-3-carboxylate chemical structure, C10H12N4O2, CAS 2091715-06-7
Methyl 6-amino-2-ethylpyrazolo[1,5-a]pyrimidine-3-carboxylate
CAS 2091715-06-7C10H12N4O2
(5-Chloropyrazolo[1,5-a]pyrimidin-2-yl)methanol chemical structure, C7H6ClN3O, CAS 1263059-09-1
(5-Chloropyrazolo[1,5-a]pyrimidin-2-yl)methanol
CAS 1263059-09-1C7H6ClN3O
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate chemical structure, C8H6ClN3O2, CAS 1263059-26-2
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS 1263059-26-2C8H6ClN3O2
5-Bromo-3-iodopyrazolo[1,5-a]pyrimidine chemical structure, C6H3BrIN3, CAS 2230052-64-7
5-Bromo-3-iodopyrazolo[1,5-a]pyrimidine
CAS 2230052-64-7C6H3BrIN3
3-Iodo-5-methoxypyrazolo[1,5-a]pyrimidine chemical structure, C7H6IN3O, CAS 1823383-09-0
3-Iodo-5-methoxypyrazolo[1,5-a]pyrimidine
CAS 1823383-09-0C7H6IN3O
Ethyl 5-chloro-7-methyl-pyrazolo[1,5-a]pyrimidine-3-carboxylate chemical structure, C10H10ClN3O2, CAS 1919821-46-7
Ethyl 5-chloro-7-methyl-pyrazolo[1,5-a]pyrimidine-3-carboxylate
CAS 1919821-46-7C10H10ClN3O2
5-Chloro-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid chemical structure, C8H6ClN3O2, CAS 1919821-45-6
5-Chloro-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid
CAS 1919821-45-6C8H6ClN3O2
Ethyl 5-chloro-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxylate chemical structure, C10H10ClN3O2, CAS 1646543-21-6
Ethyl 5-chloro-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxylate
CAS 1646543-21-6C10H10ClN3O2
Ethyl 2-bromo-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxylate chemical structure, C10H10BrN3O2, CAS 1646543-53-4
Ethyl 2-bromo-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxylate
CAS 1646543-53-4C10H10BrN3O2
tert-Butyl 5-chloro-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxylate chemical structure, C12H14ClN3O2, CAS 1646543-46-5
tert-Butyl 5-chloro-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxylate
CAS 1646543-46-5C12H14ClN3O2
Ethyl 2-chloro-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxylate chemical structure, C10H10ClN3O2, CAS 1646543-54-5
Ethyl 2-chloro-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxylate
CAS 1646543-54-5C10H10ClN3O2
Ethyl 5,6-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxylate chemical structure, C11H13N3O2, CAS 1646543-22-7
Ethyl 5,6-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxylate
CAS 1646543-22-7C11H13N3O2
5-Chloro-3-methylpyrazolo(1,5-a)pyrimidine chemical structure, C7H6ClN3, CAS 2143554-22-5
5-Chloro-3-methylpyrazolo(1,5-a)pyrimidine
CAS 2143554-22-5C7H6ClN3
3-Cyanopyrazolo[1,5-a]pyrimidine-6-sulfonyl chloride chemical structure, C7H3ClN4O2S, CAS 1909325-11-6
3-Cyanopyrazolo[1,5-a]pyrimidine-6-sulfonyl chloride
CAS 1909325-11-6C7H3ClN4O2S
N-(2-{3-Chloropyrazolo[1,5-a]pyrimidin-6-yl}ethyl)prop-2-enamide chemical structure, C11H11ClN4O, CAS 2094716-16-0
N-(2-{3-Chloropyrazolo[1,5-a]pyrimidin-6-yl}ethyl)prop-2-enamide
CAS 2094716-16-0C11H11ClN4O