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Murcko scaffold

Pyrazolo(1,5-a)pyrimidine scaffold

2,195 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
9
Chemicals
2,195
With full pages
244
Scaffold SMILES

c1cnc2ccnn2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Pyrazolo(1,5-a)pyrimidine page
Murcko scaffold c1cnc2ccnn2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1,201 to 1,248 of 2,195 chemicals

tert-Butyl N-{7-aminopyrazolo[1,5-a]pyrimidin-5-yl}carbamate chemical structure, C11H15N5O2, CAS 2059927-70-5
tert-Butyl N-{7-aminopyrazolo[1,5-a]pyrimidin-5-yl}carbamate
CAS 2059927-70-5C11H15N5O2
5-Chloropyrazolo[1,5-a]pyrimidine-3-sulfonamide chemical structure, C6H5ClN4O2S, CAS 2060045-98-7
5-Chloropyrazolo[1,5-a]pyrimidine-3-sulfonamide
CAS 2060045-98-7C6H5ClN4O2S
Pyrazolo[1,5-a]pyrimidine-2,7-dicarboxylic acid chemical structure, C8H5N3O4, CAS 2059944-29-3
Pyrazolo[1,5-a]pyrimidine-2,7-dicarboxylic acid
CAS 2059944-29-3C8H5N3O4
2-Bromopyrazolo[1,5-a]pyrimidine-7-carboxylic acid chemical structure, C7H4BrN3O2, CAS 2060048-43-1
2-Bromopyrazolo[1,5-a]pyrimidine-7-carboxylic acid
CAS 2060048-43-1C7H4BrN3O2
2-(Aminomethyl)pyrazolo[1,5-a]pyrimidine-7-carboxylic acid chemical structure, C8H8N4O2, CAS 2059954-42-4
2-(Aminomethyl)pyrazolo[1,5-a]pyrimidine-7-carboxylic acid
CAS 2059954-42-4C8H8N4O2
2-Chloropyrazolo[1,5-a]pyrimidine-7-carboxylic acid chemical structure, C7H4ClN3O2, CAS 2060061-39-2
2-Chloropyrazolo[1,5-a]pyrimidine-7-carboxylic acid
CAS 2060061-39-2C7H4ClN3O2
2-Formylpyrazolo[1,5-a]pyrimidine-7-carboxylic acid chemical structure, C8H5N3O3, CAS 2059987-45-8
2-Formylpyrazolo[1,5-a]pyrimidine-7-carboxylic acid
CAS 2059987-45-8C8H5N3O3
5-Chloropyrazolo(1,5-a)pyrimidine-3-sulfonyl fluoride chemical structure, C6H3ClFN3O2S, CAS 2059948-79-5
5-Chloropyrazolo(1,5-a)pyrimidine-3-sulfonyl fluoride
CAS 2059948-79-5C6H3ClFN3O2S
6-Chloropyrazolo[1,5-a]pyrimidine-3-sulfonamide chemical structure, C6H5ClN4O2S, CAS 2060038-40-4
6-Chloropyrazolo[1,5-a]pyrimidine-3-sulfonamide
CAS 2060038-40-4C6H5ClN4O2S
2-Aminopyrazolo[1,5-a]pyrimidine-7-carboxylic acid chemical structure, C7H6N4O2, CAS 2060031-45-8
2-Aminopyrazolo[1,5-a]pyrimidine-7-carboxylic acid
CAS 2060031-45-8C7H6N4O2
5-Fluoropyrazolo[1,5-a]pyrimidine chemical structure, C6H4FN3, CAS 2059932-25-9
5-Fluoropyrazolo[1,5-a]pyrimidine
CAS 2059932-25-9C6H4FN3
2-Chloro-7-(1,1-dimethylethyl)pyrazolo[1,5-a]pyrimidine-6-carboxylic acid chemical structure, C11H12ClN3O2, CAS 1832580-92-3
2-Chloro-7-(1,1-dimethylethyl)pyrazolo[1,5-a]pyrimidine-6-carboxylic acid
CAS 1832580-92-3C11H12ClN3O2
tert-Butyl 3-bromopyrazolo[1,5-a]pyrimidin-6-ylcarbamate chemical structure, C11H13BrN4O2, CAS 2007920-62-7
tert-Butyl 3-bromopyrazolo[1,5-a]pyrimidin-6-ylcarbamate
CAS 2007920-62-7C11H13BrN4O2
6-Bromo-3-chloropyrazolo(1,5-a)pyrimidine chemical structure, C6H3BrClN3, CAS 1958106-07-4
6-Bromo-3-chloropyrazolo(1,5-a)pyrimidine
CAS 1958106-07-4C6H3BrClN3
Ethyl 2,6-dimethylpyrazolo[1,5-A]pyrimidine-3-carboxylate chemical structure, C11H13N3O2, CAS 2093956-44-4
Ethyl 2,6-dimethylpyrazolo[1,5-A]pyrimidine-3-carboxylate
CAS 2093956-44-4C11H13N3O2
6-Bromo-2-methoxypyrazolo[1,5-a]pyrimidine chemical structure, C7H6BrN3O, CAS 2092310-45-5
6-Bromo-2-methoxypyrazolo[1,5-a]pyrimidine
CAS 2092310-45-5C7H6BrN3O
6-Bromo-3-iodo-2-methoxypyrazolo[1,5-a]pyrimidine chemical structure, C7H5BrIN3O, CAS 2094638-75-0
6-Bromo-3-iodo-2-methoxypyrazolo[1,5-a]pyrimidine
CAS 2094638-75-0C7H5BrIN3O
5-Methyl-7-(prop-2-en-1-yloxy)pyrazolo[1,5-a]pyrimidine chemical structure, C10H11N3O, CAS 2168204-20-2
5-Methyl-7-(prop-2-en-1-yloxy)pyrazolo[1,5-a]pyrimidine
CAS 2168204-20-2C10H11N3O
5-Methyl-7-[(1,1,1-trifluoropropan-2-yl)oxy]pyrazolo[1,5-a]pyrimidine chemical structure, C10H10F3N3O, CAS 2200617-67-8
5-Methyl-7-[(1,1,1-trifluoropropan-2-yl)oxy]pyrazolo[1,5-a]pyrimidine
CAS 2200617-67-8C10H10F3N3O
2,5-Dimethyl-7-(prop-2-en-1-yloxy)pyrazolo[1,5-a]pyrimidine chemical structure, C11H13N3O, CAS 2168281-59-0
2,5-Dimethyl-7-(prop-2-en-1-yloxy)pyrazolo[1,5-a]pyrimidine
CAS 2168281-59-0C11H13N3O
5-Chloro-2-fluoro-3-iodopyrazolo[1,5-a]pyrimidine chemical structure, C6H2ClFIN3, CAS 1638771-79-5
5-Chloro-2-fluoro-3-iodopyrazolo[1,5-a]pyrimidine
CAS 1638771-79-5C6H2ClFIN3
6-Chloro-5,7-dimethylpyrazolo[1,5-a]pyrimidin-2-yl acetate chemical structure, C10H10ClN3O2, CAS 89355-79-3
6-Chloro-5,7-dimethylpyrazolo[1,5-a]pyrimidin-2-yl acetate
CAS 89355-79-3C10H10ClN3O2
6-Chloro-5-methylpyrazolo[1,5-a]pyrimidin-2-yl acetate chemical structure, C9H8ClN3O2, CAS 89355-95-3
6-Chloro-5-methylpyrazolo[1,5-a]pyrimidin-2-yl acetate
CAS 89355-95-3C9H8ClN3O2
3-Bromo-2,5-dimethylpyrazolo[1,5-a]pyrimidine chemical structure, C8H8BrN3, CAS 1975118-29-6
3-Bromo-2,5-dimethylpyrazolo[1,5-a]pyrimidine
CAS 1975118-29-6C8H8BrN3