Free for buyers, contact details stay privateFree for buyers. Your contact details stay private until you accept a quote.

Sign in Join free

Murcko scaffold

Ring system with 4 rings and 26 atoms

113 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 26
Chemicals: 113
With full pages: 3

Scaffold SMILES

O=C1C(=O)N(c2ccccc2)C(c2ccccc2)C1=Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C1C(=O)N(c2ccccc2)C(c2ccccc2)C1=Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 97 to 113 of 113 chemicals

5-(2-Fluorophenyl)-3-hydroxy-4-(4-methoxybenzoyl)-1-(4-methoxyphenyl)-1H-pyrrol-2(5H)-one chemical structure, C25H20FNO5, CAS 331751-35-0

5-(2-Fluorophenyl)-3-hydroxy-4-(4-methoxybenzoyl)-1-(4-methoxyphenyl)-1H-pyrrol-2(5H)-one

CAS 331751-35-0C₂₅H₂₀FNO₅

5-(4-Bromophenyl)-3-hydroxy-4-(4-methylbenzoyl)-1-phenyl-1H-pyrrol-2(5H)-one chemical structure, C24H18BrNO3, CAS 331751-54-3

5-(4-Bromophenyl)-3-hydroxy-4-(4-methylbenzoyl)-1-phenyl-1H-pyrrol-2(5H)-one

CAS 331751-54-3C₂₄H₁₈BrNO₃

(4E)-5-(4-Fluorophenyl)-4-[hydroxy-(4-nitrophenyl)methylidene]-1-(4-methoxyphenyl)pyrrolidine-2,3-dione chemical structure, C24H17FN2O6, CAS 425416-25-7

(4E)-5-(4-Fluorophenyl)-4-[hydroxy-(4-nitrophenyl)methylidene]-1-(4-methoxyphenyl)pyrrolidine-2,3-dione

CAS 425416-25-7C₂₄H₁₇FN₂O₆

3-Hydroxy-4-(4-methylbenzoyl)-5-(4-nitrophenyl)-1-phenyl-1H-pyrrol-2(5H)-one chemical structure, C24H18N2O5, CAS 331751-56-5

3-Hydroxy-4-(4-methylbenzoyl)-5-(4-nitrophenyl)-1-phenyl-1H-pyrrol-2(5H)-one

CAS 331751-56-5C₂₄H₁₈N₂O₅

(4E)-5-(4-Chlorophenyl)-4-[(4-chlorophenyl)(hydroxy)methylidene]-1-[3-(trifluoromethyl)phenyl]pyrrolidine-2,3-dione chemical structure, C24H14Cl2F3NO3, CAS 331751-27-0

(4E)-5-(4-Chlorophenyl)-4-[(4-chlorophenyl)(hydroxy)methylidene]-1-[3-(trifluoromethyl)phenyl]pyrrolidine-2,3-dione

CAS 331751-27-0C₂₄H₁₄Cl₂F₃NO₃

(4E)-1-(4-Chlorophenyl)-5-(2-fluorophenyl)-4-[hydroxy(phenyl)methylidene]pyrrolidine-2,3-dione chemical structure, C23H15ClFNO3, CAS 331751-34-9

(4E)-1-(4-Chlorophenyl)-5-(2-fluorophenyl)-4-[hydroxy(phenyl)methylidene]pyrrolidine-2,3-dione

CAS 331751-34-9C₂₃H₁₅ClFNO₃

(4E)-1-(4-Chlorophenyl)-5-(3,4-dimethoxyphenyl)-4-[hydroxy(phenyl)methylidene]pyrrolidine-2,3-dione chemical structure, C25H20ClNO5, CAS 425414-36-4

(4E)-1-(4-Chlorophenyl)-5-(3,4-dimethoxyphenyl)-4-[hydroxy(phenyl)methylidene]pyrrolidine-2,3-dione

CAS 425414-36-4C₂₅H₂₀ClNO₅

(4E)-1-(3-Bromophenyl)-4-[hydroxy(phenyl)methylidene]-5-(4-nitrophenyl)pyrrolidine-2,3-dione chemical structure, C23H15BrN2O5, CAS 371209-80-2

(4E)-1-(3-Bromophenyl)-4-[hydroxy(phenyl)methylidene]-5-(4-nitrophenyl)pyrrolidine-2,3-dione

CAS 371209-80-2C₂₃H₁₅BrN₂O₅

4-(4-Fluorobenzoyl)-3-hydroxy-5-phenyl-1-[3-(trifluoromethyl)phenyl]-1,5-dihydro-2H-pyrrol-2-one chemical structure, C24H15F4NO3, CAS 488122-55-0

4-(4-Fluorobenzoyl)-3-hydroxy-5-phenyl-1-[3-(trifluoromethyl)phenyl]-1,5-dihydro-2H-pyrrol-2-one

CAS 488122-55-0C₂₄H₁₅F₄NO₃

4-(2-(4-Chlorophenyl)-4-hydroxy-3-(4-methylbenzoyl)-5-oxo-2,5-dihydro-1H-pyrrol-1-yl)benzenesulfonamide chemical structure, C24H19ClN2O5S, CAS 307541-88-4

4-(2-(4-Chlorophenyl)-4-hydroxy-3-(4-methylbenzoyl)-5-oxo-2,5-dihydro-1H-pyrrol-1-yl)benzenesulfonamide

CAS 307541-88-4C₂₄H₁₉ClN₂O₅S

4-Benzoyl-5-(2,4-dimethoxyphenyl)-3-hydroxy-1-(3-nitrophenyl)-1,5-dihydro-2H-pyrrol-2-one chemical structure, C25H20N2O7, CAS 423739-53-1

4-Benzoyl-5-(2,4-dimethoxyphenyl)-3-hydroxy-1-(3-nitrophenyl)-1,5-dihydro-2H-pyrrol-2-one

CAS 423739-53-1C₂₅H₂₀N₂O₇

3-Hydroxy-4-(4-methylbenzoyl)-5-(3-nitrophenyl)-1-phenyl-1H-pyrrol-2(5H)-one chemical structure, C24H18N2O5, CAS 331751-57-6

3-Hydroxy-4-(4-methylbenzoyl)-5-(3-nitrophenyl)-1-phenyl-1H-pyrrol-2(5H)-one

CAS 331751-57-6C₂₄H₁₈N₂O₅

4-(2-(3-Chlorophenyl)-4-hydroxy-3-(4-methylbenzoyl)-5-oxo-2,5-dihydro-1H-pyrrol-1-yl)benzenesulfonamide chemical structure, C24H19ClN2O5S, CAS 406200-42-8

4-(2-(3-Chlorophenyl)-4-hydroxy-3-(4-methylbenzoyl)-5-oxo-2,5-dihydro-1H-pyrrol-1-yl)benzenesulfonamide

CAS 406200-42-8C₂₄H₁₉ClN₂O₅S

4-[2-(3-Chlorophenyl)-3-[hydroxy-(4-methylphenyl)methylidene]-4,5-dioxopyrrolidin-1-yl]benzenesulfonamide chemical structure, C24H19ClN2O5S

4-[2-(3-Chlorophenyl)-3-[hydroxy-(4-methylphenyl)methylidene]-4,5-dioxopyrrolidin-1-yl]benzenesulfonamide

C₂₄H₁₉ClN₂O₅S

2H-Pyrrol-2-one, 4-(4-bromobenzoyl)-1-(4-butylphenyl)-5-(4-ethoxyphenyl)-1,5-dihydro-3-hydroxy- chemical structure, C29H28BrNO4, CAS 2121970-00-9

2H-Pyrrol-2-one, 4-(4-bromobenzoyl)-1-(4-butylphenyl)-5-(4-ethoxyphenyl)-1,5-dihydro-3-hydroxy-

CAS 2121970-00-9C₂₉H₂₈BrNO₄

4-[2-(3-Chlorophenyl)-4-hydroxy-3-(4-methylbenzoyl)-5-oxo-2,5-dihydro-1H-pyrrol-1-yl]benzene-1-sulfonamide chemical structure, C24H19ClN2O5S

4-[2-(3-Chlorophenyl)-4-hydroxy-3-(4-methylbenzoyl)-5-oxo-2,5-dihydro-1H-pyrrol-1-yl]benzene-1-sulfonamide

C₂₄H₁₉ClN₂O₅S

2H-Pyrrol-2-one, 1-[4-(1,1-dimethylethyl)phenyl]-4-(3-ethoxybenzoyl)-1,5-dihydro-3-hydroxy-5-[3-methoxy-4-(1-methylethoxy)phenyl]- chemical structure, C33H37NO6, CAS 2121991-20-4

2H-Pyrrol-2-one, 1-[4-(1,1-dimethylethyl)phenyl]-4-(3-ethoxybenzoyl)-1,5-dihydro-3-hydroxy-5-[3-methoxy-4-(1-methylethoxy)phenyl]-

CAS 2121991-20-4C₃₃H₃₇NO₆