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Murcko scaffold

1-Benzyl-6-oxo-N-phenyl-1,6-dihydro-3-pyridinecarboxamide scaffold

580 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
580
With full pages
3
Scaffold SMILES

O=C(Nc1ccccc1)c1ccc(=O)n(Cc2ccccc2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-Benzyl-6-oxo-N-phenyl-1,6-dihydro-3-pyridinecarboxamide page
Murcko scaffold O=C(Nc1ccccc1)c1ccc(=O)n(Cc2ccccc2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 580 chemicals

6-Oxo-N-[4-(trifluoromethyl)phenyl]-1-[[4-(trifluoromethyl)phenyl]methyl]pyridine-3-carboxamide chemical structure, C21H14F6N2O2, CAS 339008-58-1
6-Oxo-N-[4-(trifluoromethyl)phenyl]-1-[[4-(trifluoromethyl)phenyl]methyl]pyridine-3-carboxamide
CAS 339008-58-1C21H14F6N2O2
6-Oxo-N-phenyl-1-[4-(trifluoromethyl)benzyl]-1,6-dihydro-3-pyridinecarboxamide chemical structure, C20H15F3N2O2, CAS 339008-59-2
6-Oxo-N-phenyl-1-[4-(trifluoromethyl)benzyl]-1,6-dihydro-3-pyridinecarboxamide
CAS 339008-59-2C20H15F3N2O2
1-(2,6-Dichlorobenzyl)-6-oxo-N-phenyl-1,6-dihydro-3-pyridinecarboxamide chemical structure, C19H14Cl2N2O2, CAS 339008-60-5
1-(2,6-Dichlorobenzyl)-6-oxo-N-phenyl-1,6-dihydro-3-pyridinecarboxamide
CAS 339008-60-5C19H14Cl2N2O2
1-[(2,6-Dichlorophenyl)methyl]-N-(2,4-difluorophenyl)-6-oxopyridine-3-carboxamide chemical structure, C19H12Cl2F2N2O2, CAS 339008-61-6
1-[(2,6-Dichlorophenyl)methyl]-N-(2,4-difluorophenyl)-6-oxopyridine-3-carboxamide
CAS 339008-61-6C19H12Cl2F2N2O2
N-(4-Chlorophenyl)-1-[(2,6-dichlorophenyl)methyl]-6-oxopyridine-3-carboxamide chemical structure, C19H13Cl3N2O2, CAS 339008-62-7
N-(4-Chlorophenyl)-1-[(2,6-dichlorophenyl)methyl]-6-oxopyridine-3-carboxamide
CAS 339008-62-7C19H13Cl3N2O2
1-[(2,6-Dichlorophenyl)methyl]-6-oxo-N-[3-(trifluoromethyl)phenyl]pyridine-3-carboxamide chemical structure, C20H13Cl2F3N2O2, CAS 339008-63-8
1-[(2,6-Dichlorophenyl)methyl]-6-oxo-N-[3-(trifluoromethyl)phenyl]pyridine-3-carboxamide
CAS 339008-63-8C20H13Cl2F3N2O2
N-(2,4-Difluorophenyl)-6-oxo-1-[[4-(trifluoromethyl)phenyl]methyl]pyridine-3-carboxamide chemical structure, C20H13F5N2O2, CAS 339008-66-1
N-(2,4-Difluorophenyl)-6-oxo-1-[[4-(trifluoromethyl)phenyl]methyl]pyridine-3-carboxamide
CAS 339008-66-1C20H13F5N2O2
N-(4-Chlorophenyl)-6-oxo-1-(4-(trifluoromethyl)benzyl)-1,6-dihydro-3-pyridinecarboxamide chemical structure, C20H14ClF3N2O2, CAS 339008-67-2
N-(4-Chlorophenyl)-6-oxo-1-(4-(trifluoromethyl)benzyl)-1,6-dihydro-3-pyridinecarboxamide
CAS 339008-67-2C20H14ClF3N2O2
1-[(3-Chlorophenyl)methyl]-6-oxo-N-phenylpyridine-3-carboxamide chemical structure, C19H15ClN2O2, CAS 478065-95-1
1-[(3-Chlorophenyl)methyl]-6-oxo-N-phenylpyridine-3-carboxamide
CAS 478065-95-1C19H15ClN2O2
1-[(3-Chlorophenyl)methyl]-N-(2,4-difluorophenyl)-6-oxopyridine-3-carboxamide chemical structure, C19H13ClF2N2O2, CAS 478065-96-2
1-[(3-Chlorophenyl)methyl]-N-(2,4-difluorophenyl)-6-oxopyridine-3-carboxamide
CAS 478065-96-2C19H13ClF2N2O2
1-Benzyl-6-oxo-N-[4-(trifluoromethyl)phenyl]-1,6-dihydropyridine-3-carboxamide chemical structure, C20H15F3N2O2, CAS 478065-98-4
1-Benzyl-6-oxo-N-[4-(trifluoromethyl)phenyl]-1,6-dihydropyridine-3-carboxamide
CAS 478065-98-4C20H15F3N2O2
1-[(2,6-Dichlorophenyl)methyl]-N-methyl-6-oxo-N-phenylpyridine-3-carboxamide chemical structure, C20H16Cl2N2O2, CAS 478065-99-5
1-[(2,6-Dichlorophenyl)methyl]-N-methyl-6-oxo-N-phenylpyridine-3-carboxamide
CAS 478065-99-5C20H16Cl2N2O2
1-Benzyl-6-oxo-N-phenyl-1,6-dihydro-3-pyridinecarboxamide chemical structure, C19H16N2O2, CAS 339008-77-4
1-Benzyl-6-oxo-N-phenyl-1,6-dihydro-3-pyridinecarboxamide
CAS 339008-77-4C19H16N2O2
1-Benzyl-6-oxo-N-[4-(trifluoromethoxy)phenyl]-1,6-dihydro-3-pyridinecarboxamide chemical structure, C20H15F3N2O3, CAS 339008-78-5
1-Benzyl-6-oxo-N-[4-(trifluoromethoxy)phenyl]-1,6-dihydro-3-pyridinecarboxamide
CAS 339008-78-5C20H15F3N2O3
1-Benzyl-N-(2,4-difluorophenyl)-6-oxo-1,6-dihydro-3-pyridinecarboxamide chemical structure, C19H14F2N2O2, CAS 339008-84-3
1-Benzyl-N-(2,4-difluorophenyl)-6-oxo-1,6-dihydro-3-pyridinecarboxamide
CAS 339008-84-3C19H14F2N2O2
5-Chloro-1-(3,4-dichlorobenzyl)-6-oxo-N-phenyl-1,6-dihydro-3-pyridinecarboxamide chemical structure, C19H13Cl3N2O2, CAS 400086-06-8
5-Chloro-1-(3,4-dichlorobenzyl)-6-oxo-N-phenyl-1,6-dihydro-3-pyridinecarboxamide
CAS 400086-06-8C19H13Cl3N2O2
5-Chloro-N-(4-chlorophenyl)-1-(3,4-dichlorobenzyl)-6-oxo-1,6-dihydro-3-pyridinecarboxamide chemical structure, C19H12Cl4N2O2, CAS 866051-40-3
5-Chloro-N-(4-chlorophenyl)-1-(3,4-dichlorobenzyl)-6-oxo-1,6-dihydro-3-pyridinecarboxamide
CAS 866051-40-3C19H12Cl4N2O2
5-Chloro-1-(3,4-dichlorobenzyl)-N-methyl-6-oxo-N-phenyl-1,6-dihydro-3-pyridinecarboxamide chemical structure, C20H15Cl3N2O2, CAS 339009-05-1
5-Chloro-1-(3,4-dichlorobenzyl)-N-methyl-6-oxo-N-phenyl-1,6-dihydro-3-pyridinecarboxamide
CAS 339009-05-1C20H15Cl3N2O2
5-Chloro-1-(2,6-dichlorobenzyl)-6-oxo-N-phenyl-1,6-dihydro-3-pyridinecarboxamide chemical structure, C19H13Cl3N2O2, CAS 400086-12-6
5-Chloro-1-(2,6-dichlorobenzyl)-6-oxo-N-phenyl-1,6-dihydro-3-pyridinecarboxamide
CAS 400086-12-6C19H13Cl3N2O2
5-Chloro-N-(4-chlorophenyl)-1-(2,6-dichlorobenzyl)-6-oxo-1,6-dihydro-3-pyridinecarboxamide chemical structure, C19H12Cl4N2O2, CAS 339023-91-5
5-Chloro-N-(4-chlorophenyl)-1-(2,6-dichlorobenzyl)-6-oxo-1,6-dihydro-3-pyridinecarboxamide
CAS 339023-91-5C19H12Cl4N2O2
5-Chloro-1-(3,4-dichlorobenzyl)-N-(4-methoxyphenyl)-6-oxo-1,6-dihydro-3-pyridinecarboxamide chemical structure, C20H15Cl3N2O3, CAS 339023-93-7
5-Chloro-1-(3,4-dichlorobenzyl)-N-(4-methoxyphenyl)-6-oxo-1,6-dihydro-3-pyridinecarboxamide
CAS 339023-93-7C20H15Cl3N2O3
5-Chloro-1-[(2,6-dichlorophenyl)methyl]-N-methyl-6-oxo-N-phenylpyridine-3-carboxamide chemical structure, C20H15Cl3N2O2, CAS 339024-00-9
5-Chloro-1-[(2,6-dichlorophenyl)methyl]-N-methyl-6-oxo-N-phenylpyridine-3-carboxamide
CAS 339024-00-9C20H15Cl3N2O2
5-Chloro-6-oxo-N-phenyl-1-[3-(trifluoromethyl)benzyl]-1,6-dihydro-3-pyridinecarboxamide chemical structure, C20H14ClF3N2O2, CAS 339024-10-1
5-Chloro-6-oxo-N-phenyl-1-[3-(trifluoromethyl)benzyl]-1,6-dihydro-3-pyridinecarboxamide
CAS 339024-10-1C20H14ClF3N2O2
5-Chloro-N-(4-chlorophenyl)-6-oxo-1-[[3-(trifluoromethyl)phenyl]methyl]pyridine-3-carboxamide chemical structure, C20H13Cl2F3N2O2, CAS 339024-12-3
5-Chloro-N-(4-chlorophenyl)-6-oxo-1-[[3-(trifluoromethyl)phenyl]methyl]pyridine-3-carboxamide
CAS 339024-12-3C20H13Cl2F3N2O2