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Murcko scaffold

4-Phenyl-2-(1H-pyrazol-1-yl)-1,3-thiazole scaffold

148 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
148
With full pages
16
Scaffold SMILES

c1ccc(-c2csc(-n3cccn3)n2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-Phenyl-2-(1H-pyrazol-1-yl)-1,3-thiazole page
Murcko scaffold c1ccc(-c2csc(-n3cccn3)n2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 97 to 144 of 148 chemicals

Ethyl 2-((3-methyl-1-(4-(p-tolyl)thiazol-2-yl)-1H-pyrazol-5-yl)amino)-2-oxoacetate chemical structure, C18H18N4O3S, CAS 1019103-46-8
Ethyl 2-((3-methyl-1-(4-(p-tolyl)thiazol-2-yl)-1H-pyrazol-5-yl)amino)-2-oxoacetate
CAS 1019103-46-8C18H18N4O3S
Ethyl 4-((3-methyl-1-(4-(p-tolyl)thiazol-2-yl)-1H-pyrazol-5-yl)amino)-4-oxobutanoate chemical structure, C20H22N4O3S, CAS 1019103-48-0
Ethyl 4-((3-methyl-1-(4-(p-tolyl)thiazol-2-yl)-1H-pyrazol-5-yl)amino)-4-oxobutanoate
CAS 1019103-48-0C20H22N4O3S
Ethyl (3-methyl-1-(4-(p-tolyl)thiazol-2-yl)-1H-pyrazol-5-yl)carbamate chemical structure, C17H18N4O2S, CAS 1019103-50-4
Ethyl (3-methyl-1-(4-(p-tolyl)thiazol-2-yl)-1H-pyrazol-5-yl)carbamate
CAS 1019103-50-4C17H18N4O2S
N-{1-[4-(4-Fluorophenyl)-1,3-thiazol-2-yl]-3-methyl-1H-pyrazol-5-yl}acetamide chemical structure, C15H13FN4OS, CAS 1019103-53-7
N-{1-[4-(4-Fluorophenyl)-1,3-thiazol-2-yl]-3-methyl-1H-pyrazol-5-yl}acetamide
CAS 1019103-53-7C15H13FN4OS
N-(1-(4-(4-Fluorophenyl)thiazol-2-yl)-3-methyl-1H-pyrazol-5-yl)pivalamide chemical structure, C18H19FN4OS, CAS 1019103-55-9
N-(1-(4-(4-Fluorophenyl)thiazol-2-yl)-3-methyl-1H-pyrazol-5-yl)pivalamide
CAS 1019103-55-9C18H19FN4OS
N-(1-(4-(4-Fluorophenyl)thiazol-2-yl)-3-methyl-1H-pyrazol-5-yl)-3-methylbutanamide chemical structure, C18H19FN4OS, CAS 1019103-57-1
N-(1-(4-(4-Fluorophenyl)thiazol-2-yl)-3-methyl-1H-pyrazol-5-yl)-3-methylbutanamide
CAS 1019103-57-1C18H19FN4OS
(Z)-N-(1-(4-(4-Fluorophenyl)thiazol-2-yl)-3-methyl-1H-pyrazol-5-yl)but-2-enamide chemical structure, C17H15FN4OS, CAS 1019103-71-9
(Z)-N-(1-(4-(4-Fluorophenyl)thiazol-2-yl)-3-methyl-1H-pyrazol-5-yl)but-2-enamide
CAS 1019103-71-9C17H15FN4OS
N-{1-[4-(4-Fluorophenyl)-1,3-thiazol-2-yl]-3-methyl-1H-pyrazol-5-yl}-2-methoxyacetamide chemical structure, C16H15FN4O2S, CAS 1019103-73-1
N-{1-[4-(4-Fluorophenyl)-1,3-thiazol-2-yl]-3-methyl-1H-pyrazol-5-yl}-2-methoxyacetamide
CAS 1019103-73-1C16H15FN4O2S
2-Ethoxy-N-{1-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]-3-methyl-1H-pyrazol-5-yl}acetamide chemical structure, C17H17FN4O2S, CAS 1019103-75-3
2-Ethoxy-N-{1-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]-3-methyl-1H-pyrazol-5-yl}acetamide
CAS 1019103-75-3C17H17FN4O2S
Ethyl 2-((1-(4-(4-fluorophenyl)thiazol-2-yl)-3-methyl-1H-pyrazol-5-yl)amino)-2-oxoacetate chemical structure, C17H15FN4O3S, CAS 1019104-65-4
Ethyl 2-((1-(4-(4-fluorophenyl)thiazol-2-yl)-3-methyl-1H-pyrazol-5-yl)amino)-2-oxoacetate
CAS 1019104-65-4C17H15FN4O3S
Ethyl 4-((1-(4-(4-fluorophenyl)thiazol-2-yl)-3-methyl-1H-pyrazol-5-yl)amino)-4-oxobutanoate chemical structure, C19H19FN4O3S, CAS 1019104-68-7
Ethyl 4-((1-(4-(4-fluorophenyl)thiazol-2-yl)-3-methyl-1H-pyrazol-5-yl)amino)-4-oxobutanoate
CAS 1019104-68-7C19H19FN4O3S
Ethyl (1-(4-(4-fluorophenyl)thiazol-2-yl)-3-methyl-1H-pyrazol-5-yl)carbamate chemical structure, C16H15FN4O2S, CAS 1019104-71-2
Ethyl (1-(4-(4-fluorophenyl)thiazol-2-yl)-3-methyl-1H-pyrazol-5-yl)carbamate
CAS 1019104-71-2C16H15FN4O2S
N-(1-(4-(3-Methoxyphenyl)thiazol-2-yl)-3-methyl-1H-pyrazol-5-yl)pentanamide chemical structure, C19H22N4O2S, CAS 1019104-74-5
N-(1-(4-(3-Methoxyphenyl)thiazol-2-yl)-3-methyl-1H-pyrazol-5-yl)pentanamide
CAS 1019104-74-5C19H22N4O2S
N-(1-(4-(3-Methoxyphenyl)thiazol-2-yl)-3-methyl-1H-pyrazol-5-yl)-3-methylbutanamide chemical structure, C19H22N4O2S, CAS 1019104-77-8
N-(1-(4-(3-Methoxyphenyl)thiazol-2-yl)-3-methyl-1H-pyrazol-5-yl)-3-methylbutanamide
CAS 1019104-77-8C19H22N4O2S
(Z)-N-(1-(4-(3-Methoxyphenyl)thiazol-2-yl)-3-methyl-1H-pyrazol-5-yl)but-2-enamide chemical structure, C18H18N4O2S, CAS 1019104-83-6
(Z)-N-(1-(4-(3-Methoxyphenyl)thiazol-2-yl)-3-methyl-1H-pyrazol-5-yl)but-2-enamide
CAS 1019104-83-6C18H18N4O2S
Ethyl ({1-[4-(3-methoxyphenyl)-1,3-thiazol-2-yl]-3-methyl-1H-pyrazol-5-yl}carbamoyl)formate chemical structure, C18H18N4O4S, CAS 1019095-44-3
Ethyl ({1-[4-(3-methoxyphenyl)-1,3-thiazol-2-yl]-3-methyl-1H-pyrazol-5-yl}carbamoyl)formate
CAS 1019095-44-3C18H18N4O4S
Ethyl N-{1-[4-(3-methoxyphenyl)-1,3-thiazol-2-yl]-3-methyl-1H-pyrazol-5-yl}carbamate chemical structure, C17H18N4O3S, CAS 1019095-45-4
Ethyl N-{1-[4-(3-methoxyphenyl)-1,3-thiazol-2-yl]-3-methyl-1H-pyrazol-5-yl}carbamate
CAS 1019095-45-4C17H18N4O3S
N-{1-[4-(4-Methoxyphenyl)-1,3-thiazol-2-yl]-3-methyl-1H-pyrazol-5-yl}butanamide chemical structure, C18H20N4O2S, CAS 1019095-46-5
N-{1-[4-(4-Methoxyphenyl)-1,3-thiazol-2-yl]-3-methyl-1H-pyrazol-5-yl}butanamide
CAS 1019095-46-5C18H20N4O2S
2-Ethyl-N-{1-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-3-methyl-1H-pyrazol-5-yl}butanamide chemical structure, C20H24N4O2S, CAS 1019095-47-6
2-Ethyl-N-{1-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-3-methyl-1H-pyrazol-5-yl}butanamide
CAS 1019095-47-6C20H24N4O2S
N-{1-[4-(4-Ethoxyphenyl)-1,3-thiazol-2-yl]-3-methyl-1H-pyrazol-5-yl}acetamide chemical structure, C17H18N4O2S, CAS 1019095-50-1
N-{1-[4-(4-Ethoxyphenyl)-1,3-thiazol-2-yl]-3-methyl-1H-pyrazol-5-yl}acetamide
CAS 1019095-50-1C17H18N4O2S
N-(1-(4-(4-Ethoxyphenyl)thiazol-2-yl)-3-methyl-1H-pyrazol-5-yl)pentanamide chemical structure, C20H24N4O2S, CAS 1019095-51-2
N-(1-(4-(4-Ethoxyphenyl)thiazol-2-yl)-3-methyl-1H-pyrazol-5-yl)pentanamide
CAS 1019095-51-2C20H24N4O2S
N-(1-(4-(4-Ethoxyphenyl)thiazol-2-yl)-3-methyl-1H-pyrazol-5-yl)pivalamide chemical structure, C20H24N4O2S, CAS 1019095-52-3
N-(1-(4-(4-Ethoxyphenyl)thiazol-2-yl)-3-methyl-1H-pyrazol-5-yl)pivalamide
CAS 1019095-52-3C20H24N4O2S
N-(1-(4-(4-Ethoxyphenyl)thiazol-2-yl)-3-methyl-1H-pyrazol-5-yl)-2-ethylbutanamide chemical structure, C21H26N4O2S, CAS 1019095-53-4
N-(1-(4-(4-Ethoxyphenyl)thiazol-2-yl)-3-methyl-1H-pyrazol-5-yl)-2-ethylbutanamide
CAS 1019095-53-4C21H26N4O2S
(Z)-N-(1-(4-(4-Ethoxyphenyl)thiazol-2-yl)-3-methyl-1H-pyrazol-5-yl)but-2-enamide chemical structure, C19H20N4O2S, CAS 1019095-56-7
(Z)-N-(1-(4-(4-Ethoxyphenyl)thiazol-2-yl)-3-methyl-1H-pyrazol-5-yl)but-2-enamide
CAS 1019095-56-7C19H20N4O2S