CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 19 atoms

28 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
28
With full pages
6
Scaffold SMILES

O=C(Nc1ccccc1)c1cnc2ccccc2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1)c1cnc2ccccc2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 28 of 28 chemicals

2-Amino-N-phenylquinoline-3-carboxamide chemical structure, C16H13N3O, CAS 121217-60-5
2-Amino-N-phenylquinoline-3-carboxamide
CAS 121217-60-5C16H13N3O
3-Quinolinecarboxamide, 2-amino-N-(4-fluorophenyl)- chemical structure, C16H12FN3O, CAS 524036-16-6
3-Quinolinecarboxamide, 2-amino-N-(4-fluorophenyl)-
CAS 524036-16-6C16H12FN3O
2-Amino-6,7-dimethoxy-N-phenylquinoline-3-carboxamide chemical structure, C18H17N3O3, CAS 405277-62-5
2-Amino-6,7-dimethoxy-N-phenylquinoline-3-carboxamide
CAS 405277-62-5C18H17N3O3
2-Amino-N-(3-chlorophenyl)quinoline-3-carboxamide chemical structure, C16H12ClN3O, CAS 446052-45-5
2-Amino-N-(3-chlorophenyl)quinoline-3-carboxamide
CAS 446052-45-5C16H12ClN3O
AF-399/42255561 chemical structure, C17H13ClN2O, CAS 6432-52-6
AF-399/42255561
CAS 6432-52-6C17H13ClN2O
N-(2-Fluorophenyl)-2-methylquinoline-3-carboxamide chemical structure, C17H13FN2O, CAS 720677-42-9
N-(2-Fluorophenyl)-2-methylquinoline-3-carboxamide
CAS 720677-42-9C17H13FN2O
3-[(2-Chlorophenyl)carbamoyl]-2-methylquinoline-4-carboxylic acid chemical structure, C18H13ClN2O3, CAS 681472-46-8
3-[(2-Chlorophenyl)carbamoyl]-2-methylquinoline-4-carboxylic acid
CAS 681472-46-8C18H13ClN2O3
3-[(2-Methoxyphenyl)carbamoyl]-2-methylquinoline-4-carboxylic acid chemical structure, C19H16N2O4, CAS 681472-44-6
3-[(2-Methoxyphenyl)carbamoyl]-2-methylquinoline-4-carboxylic acid
CAS 681472-44-6C19H16N2O4
2-Chloro-N-[2-chloro-5-(trifluoromethyl)phenyl]quinoline-3-carboxamide chemical structure, C17H9Cl2F3N2O, CAS 325742-97-0
2-Chloro-N-[2-chloro-5-(trifluoromethyl)phenyl]quinoline-3-carboxamide
CAS 325742-97-0C17H9Cl2F3N2O
2-Chloro-N-(2-nitrophenyl)quinoline-3-carboxamide chemical structure, C16H10ClN3O3, CAS 325731-75-7
2-Chloro-N-(2-nitrophenyl)quinoline-3-carboxamide
CAS 325731-75-7C16H10ClN3O3
N-(2-Bromo-4-nitrophenyl)-2-chloroquinoline-3-carboxamide chemical structure, C16H9BrClN3O3, CAS 325747-60-2
N-(2-Bromo-4-nitrophenyl)-2-chloroquinoline-3-carboxamide
CAS 325747-60-2C16H9BrClN3O3
2-Chloro-N-(4-chloro-2-nitrophenyl)quinoline-3-carboxamide chemical structure, C16H9Cl2N3O3, CAS 325742-75-4
2-Chloro-N-(4-chloro-2-nitrophenyl)quinoline-3-carboxamide
CAS 325742-75-4C16H9Cl2N3O3
2-Chloro-N-(4-nitrophenyl)quinoline-3-carboxamide chemical structure, C16H10ClN3O3, CAS 325731-70-2
2-Chloro-N-(4-nitrophenyl)quinoline-3-carboxamide
CAS 325731-70-2C16H10ClN3O3
2-Amino-N-(4-methylphenyl)-3-quinolinecarboxamide chemical structure, C17H15N3O, CAS 121217-61-6
2-Amino-N-(4-methylphenyl)-3-quinolinecarboxamide
CAS 121217-61-6C17H15N3O
2-Amino-N-(4-methoxyphenyl)quinoline-3-carboxamide chemical structure, C17H15N3O2, CAS 121217-62-7
2-Amino-N-(4-methoxyphenyl)quinoline-3-carboxamide
CAS 121217-62-7C17H15N3O2
N-(3-Nitrophenyl)-3-quinolinecarboxamide chemical structure, C16H11N3O3, CAS 176033-45-7
N-(3-Nitrophenyl)-3-quinolinecarboxamide
CAS 176033-45-7C16H11N3O3
N-(3-Hydroxy-4-tert-butyl-phenyl)-4-methoxy-quinoline-3-carboxamide chemical structure, C21H22N2O3, CAS 873054-26-3
N-(3-Hydroxy-4-tert-butyl-phenyl)-4-methoxy-quinoline-3-carboxamide
CAS 873054-26-3C21H22N2O3
2,4-Dimethoxy-N-(2-tert-butylphenyl)-quinoline-3-carboxamide chemical structure, C22H24N2O3, CAS 873053-09-9
2,4-Dimethoxy-N-(2-tert-butylphenyl)-quinoline-3-carboxamide
CAS 873053-09-9C22H24N2O3
2-Chloro-N-(2-chloro-5-propanamidophenyl)-6-methoxyquinoline-3-carboxamide chemical structure, C20H17Cl2N3O3, CAS 1427678-83-8
2-Chloro-N-(2-chloro-5-propanamidophenyl)-6-methoxyquinoline-3-carboxamide
CAS 1427678-83-8C20H17Cl2N3O3
2,4-Dichloro-N-(3-chloro-4-methylphenyl)quinoline-3-carboxamide chemical structure, C17H11Cl3N2O, CAS 1427678-21-4
2,4-Dichloro-N-(3-chloro-4-methylphenyl)quinoline-3-carboxamide
CAS 1427678-21-4C17H11Cl3N2O
2-Amino-N-(2,3-dichlorophenyl)quinoline-3-carboxamide chemical structure, C16H11Cl2N3O, CAS 2096986-35-3
2-Amino-N-(2,3-dichlorophenyl)quinoline-3-carboxamide
CAS 2096986-35-3C16H11Cl2N3O
2-Chloro-N-(2,4-difluorophenyl)-6-methoxyquinoline-3-carboxamide chemical structure, C17H11ClF2N2O2, CAS 1808766-71-3
2-Chloro-N-(2,4-difluorophenyl)-6-methoxyquinoline-3-carboxamide
CAS 1808766-71-3C17H11ClF2N2O2
N-(3-acetylphenyl)-3-Quinolinecarboxamide chemical structure, C18H14N2O2, CAS 1039454-73-3
N-(3-acetylphenyl)-3-Quinolinecarboxamide
CAS 1039454-73-3C18H14N2O2
N-(4-acetylphenyl)-3-Quinolinecarboxamide chemical structure, C18H14N2O2, CAS 1039454-75-5
N-(4-acetylphenyl)-3-Quinolinecarboxamide
CAS 1039454-75-5C18H14N2O2