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Murcko scaffold

1-Oxa-3,8-diazaspiro(4.5)decan 2-one scaffold

35 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
35
With full pages
3
Scaffold SMILES

O=C1NCC2(CCNCC2)O1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-Oxa-3,8-diazaspiro(4.5)decan 2-one page
Murcko scaffold O=C1NCC2(CCNCC2)O1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 35 of 35 chemicals

1-Oxa-3,8-diazaspiro(4.5)decan-2-one, 8-dimethylsulfamoyl-, hydrochloride chemical structure, C9H18ClN3O4S, CAS 74195-70-3
1-Oxa-3,8-diazaspiro(4.5)decan-2-one, 8-dimethylsulfamoyl-, hydrochloride
CAS 74195-70-3C9H18ClN3O4S
tert-Butyl 2-oxo-1-oxa-3,8-diazaspiro[4.5]decane-8-carboxylate chemical structure, C12H20N2O4, CAS 169206-55-7
tert-Butyl 2-oxo-1-oxa-3,8-diazaspiro[4.5]decane-8-carboxylate
CAS 169206-55-7C12H20N2O4
1-Oxa-3,8-diazaspiro[4.5]decane-8-carboxylic acid, 3-methyl-2-oxo-, 1,1-dimethylethyl ester chemical structure, C13H22N2O4, CAS 613675-35-7
1-Oxa-3,8-diazaspiro[4.5]decane-8-carboxylic acid, 3-methyl-2-oxo-, 1,1-dimethylethyl ester
CAS 613675-35-7C13H22N2O4
3-Methyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one chemical structure, C8H14N2O2, CAS 77225-15-1
3-Methyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one
CAS 77225-15-1C8H14N2O2
1-Oxa-3,8-diazaspiro(4.5)decan 2-one chemical structure, C7H12N2O2, CAS 5052-95-9
1-Oxa-3,8-diazaspiro(4.5)decan 2-one
CAS 5052-95-9C7H12N2O2
4-Methyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one chemical structure, C8H14N2O2, CAS 40131-54-2
4-Methyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one
CAS 40131-54-2C8H14N2O2
3-tert-Butyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one chemical structure, C11H20N2O2, CAS 187397-04-2
3-tert-Butyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one
CAS 187397-04-2C11H20N2O2
4-Hydroxy-4-methyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one chemical structure, C8H14N2O3, CAS 134347-95-8
4-Hydroxy-4-methyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one
CAS 134347-95-8C8H14N2O3
3-Propyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one chemical structure, C10H18N2O2, CAS 77211-52-0
3-Propyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one
CAS 77211-52-0C10H18N2O2
3-Isopropyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one chemical structure, C10H18N2O2, CAS 77211-53-1
3-Isopropyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one
CAS 77211-53-1C10H18N2O2
3-Ethyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one chemical structure, C9H16N2O2, CAS 77211-51-9
3-Ethyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one
CAS 77211-51-9C9H16N2O2
4,4-Dimethyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one chemical structure, C9H16N2O2, CAS 77211-49-5
4,4-Dimethyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one
CAS 77211-49-5C9H16N2O2
3-Butyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one chemical structure, C11H20N2O2, CAS 77211-54-2
3-Butyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one
CAS 77211-54-2C11H20N2O2
4-Ethyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one chemical structure, C9H16N2O2, CAS 23484-71-1
4-Ethyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one
CAS 23484-71-1C9H16N2O2
tert-Butyl 2-{2-oxo-1-oxa-3,8-diazaspiro[4.5]decan-3-yl}acetate chemical structure, C13H22N2O4, CAS 189333-69-5
tert-Butyl 2-{2-oxo-1-oxa-3,8-diazaspiro[4.5]decan-3-yl}acetate
CAS 189333-69-5C13H22N2O4
2-{2-Oxo-1-oxa-3,8-diazaspiro[4.5]decan-3-yl}acetic acid chemical structure, C9H14N2O4, CAS 1785198-51-7
2-{2-Oxo-1-oxa-3,8-diazaspiro[4.5]decan-3-yl}acetic acid
CAS 1785198-51-7C9H14N2O4
4,8-Diethyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one chemical structure, C11H20N2O2, CAS 730911-77-0
4,8-Diethyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one
CAS 730911-77-0C11H20N2O2
1-Oxa-3,8-diazaspiro[4.5]decan-2-one, 6-ethyl- chemical structure, C9H16N2O2, CAS 79053-06-8
1-Oxa-3,8-diazaspiro[4.5]decan-2-one, 6-ethyl-
CAS 79053-06-8C9H16N2O2
3-Methyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one hydrochloride chemical structure, C8H15ClN2O2, CAS 613675-34-6
3-Methyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one hydrochloride
CAS 613675-34-6C8H15ClN2O2
1-Oxa-3,8-diazaspiro[4.5]decan-2-one hydrochloride chemical structure, C7H13ClN2O2, CAS 5052-96-0
1-Oxa-3,8-diazaspiro[4.5]decan-2-one hydrochloride
CAS 5052-96-0C7H13ClN2O2
8-Methyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one chemical structure, C8H14N2O2, CAS 5053-07-6
8-Methyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one
CAS 5053-07-6C8H14N2O2
3-(2-Methylpropyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one chemical structure, C11H20N2O2, CAS 1781903-70-5
3-(2-Methylpropyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one
CAS 1781903-70-5C11H20N2O2
3-Ethyl-1-oxa-3,8-diazaspiro(4.5)decan-2-one hydrochloride chemical structure, C9H17ClN2O2, CAS 1896915-28-8
3-Ethyl-1-oxa-3,8-diazaspiro(4.5)decan-2-one hydrochloride
CAS 1896915-28-8C9H17ClN2O2
8-Methyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one hydrochloride chemical structure, C8H15ClN2O2, CAS 5053-10-1
8-Methyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one hydrochloride
CAS 5053-10-1C8H15ClN2O2