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Murcko scaffold

Ring system with 3 rings and 21 atoms

10 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
10
With full pages
1
Scaffold SMILES

O=C(NCc1coc(-c2ccccc2)n1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCc1coc(-c2ccccc2)n1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

N-[2-(4-Difluoromethoxy-3-isobutoxyphenyl)oxazol-4-ylmethyl]-2-ethoxybenzamide chemical structure, C24H26F2N2O5, CAS 937782-01-9
N-[2-(4-Difluoromethoxy-3-isobutoxyphenyl)oxazol-4-ylmethyl]-2-ethoxybenzamide
CAS 937782-01-9C24H26F2N2O5
N-[2-(4-Difluoromethoxy-3-ethoxyphenyl)oxazol-4-ylmethyl]-2-ethoxybenzamide chemical structure, C22H22F2N2O5, CAS 937782-02-0
N-[2-(4-Difluoromethoxy-3-ethoxyphenyl)oxazol-4-ylmethyl]-2-ethoxybenzamide
CAS 937782-02-0C22H22F2N2O5
Difamilast chemical structure, C23H24F2N2O5, CAS 937782-05-3
Difamilast
CAS 937782-05-3C23H24F2N2O5
N-[2-(4-Difluoromethoxy-3-hydroxyphenyl)oxazol-4-ylmethyl]-2-ethoxybenzamide chemical structure, C20H18F2N2O5, CAS 937782-00-8
N-[2-(4-Difluoromethoxy-3-hydroxyphenyl)oxazol-4-ylmethyl]-2-ethoxybenzamide
CAS 937782-00-8C20H18F2N2O5
Difamilast impurity 5 chemical structure, C21H20F2N2O6, CAS 2103190-81-2
Difamilast impurity 5
CAS 2103190-81-2C21H20F2N2O6
Difamilast impurity 2 chemical structure, C23H24F2N2O6, CAS 2103190-94-7
Difamilast impurity 2
CAS 2103190-94-7C23H24F2N2O6
Difamilast impurity 11 chemical structure, C23H24F2N2O7, CAS 2103190-98-1
Difamilast impurity 11
CAS 2103190-98-1C23H24F2N2O7
Difamilast impurity 8 chemical structure, C21H20F2N2O6, CAS 2103190-85-6
Difamilast impurity 8
CAS 2103190-85-6C21H20F2N2O6
Difamilast impurity 10 chemical structure, C21H20F2N2O5, CAS 2103190-58-3
Difamilast impurity 10
CAS 2103190-58-3C21H20F2N2O5
Difamilast impurity 4 chemical structure, C23H24F2N2O6, CAS 2103190-65-2
Difamilast impurity 4
CAS 2103190-65-2C23H24F2N2O6