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Murcko scaffold

N-Phenethyl phthalimide scaffold

119 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
119
With full pages
19
Scaffold SMILES

O=C1c2ccccc2C(=O)N1CCc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-Phenethyl phthalimide page
Murcko scaffold O=C1c2ccccc2C(=O)N1CCc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 119 chemicals

2-Isoindolineacetic acid, 1,3-dioxo-alpha-(4-hydroxy-3-nitrobenzyl)- chemical structure, C17H12N2O7, CAS 73837-59-9
2-Isoindolineacetic acid, 1,3-dioxo-alpha-(4-hydroxy-3-nitrobenzyl)-
CAS 73837-59-9C17H12N2O7
Ethyl 2-(1,3-dioxoisoindol-2-yl)-3-(4-nitrophenyl)propanoate chemical structure, C19H16N2O6, CAS 17451-67-1
Ethyl 2-(1,3-dioxoisoindol-2-yl)-3-(4-nitrophenyl)propanoate
CAS 17451-67-1C19H16N2O6
Ethyl 3-(4-aminophenyl)-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propanoate chemical structure, C19H18N2O4, CAS 6957-96-6
Ethyl 3-(4-aminophenyl)-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propanoate
CAS 6957-96-6C19H18N2O4
2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-(4-nitrophenyl)propanoic acid chemical structure, C17H12N2O6, CAS 5467-31-2
2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-(4-nitrophenyl)propanoic acid
CAS 5467-31-2C17H12N2O6
N-Phthaloyl-DL-phenylalanine chemical structure, C17H13NO4, CAS 38229-08-2
N-Phthaloyl-DL-phenylalanine
CAS 38229-08-2C17H13NO4
Methyl 2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-phenylpropanoate chemical structure, C18H15NO4, CAS 7146-63-6
Methyl 2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-phenylpropanoate
CAS 7146-63-6C18H15NO4
2-(1,3-Dioxoisoindol-2-yl)-3-(3-nitrophenyl)propanoic acid chemical structure, C17H12N2O6, CAS 5461-86-9
2-(1,3-Dioxoisoindol-2-yl)-3-(3-nitrophenyl)propanoic acid
CAS 5461-86-9C17H12N2O6
Methyl 2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-(3-nitrophenyl)propanoate chemical structure, C18H14N2O6, CAS 5461-87-0
Methyl 2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-(3-nitrophenyl)propanoate
CAS 5461-87-0C18H14N2O6
Methyl 3-{3-[bis(2-chloroethyl)amino]phenyl}-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propanoate chemical structure, C22H22Cl2N2O4, CAS 6970-44-1
Methyl 3-{3-[bis(2-chloroethyl)amino]phenyl}-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propanoate
CAS 6970-44-1C22H22Cl2N2O4
Methyl 3-{3-[bis(2-hydroxyethyl)amino]phenyl}-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propanoate chemical structure, C22H24N2O6, CAS 5461-88-1
Methyl 3-{3-[bis(2-hydroxyethyl)amino]phenyl}-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propanoate
CAS 5461-88-1C22H24N2O6
Methyl 2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-(4-nitrophenyl)propanoate chemical structure, C18H14N2O6, CAS 5472-61-7
Methyl 2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-(4-nitrophenyl)propanoate
CAS 5472-61-7C18H14N2O6
2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-(4-hydroxyphenyl)propanoic acid chemical structure, C17H13NO5, CAS 98029-78-8
2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-(4-hydroxyphenyl)propanoic acid
CAS 98029-78-8C17H13NO5
Methyl 3-[4-(chloromethyl)phenyl]-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propanoate chemical structure, C19H16ClNO4, CAS 6336-18-1
Methyl 3-[4-(chloromethyl)phenyl]-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propanoate
CAS 6336-18-1C19H16ClNO4
2-(1,3-Dioxoisoindol-2-yl)-3-(2-nitrophenyl)propanoic acid chemical structure, C17H12N2O6, CAS 7150-50-7
2-(1,3-Dioxoisoindol-2-yl)-3-(2-nitrophenyl)propanoic acid
CAS 7150-50-7C17H12N2O6
N-(2-Hydroxy-1-benzylethyl)phthalimide chemical structure, C17H15NO3, CAS 93316-45-1
N-(2-Hydroxy-1-benzylethyl)phthalimide
CAS 93316-45-1C17H15NO3
2-[2-(2-Bromophenyl)ethyl]isoindole-1,3-dione chemical structure, C16H12BrNO2, CAS 75767-95-2
2-[2-(2-Bromophenyl)ethyl]isoindole-1,3-dione
CAS 75767-95-2C16H12BrNO2
(2S)-2-(1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl)-3-phenylpropanoic acid chemical structure, C17H13NO4, CAS 5123-55-7
(2S)-2-(1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl)-3-phenylpropanoic acid
CAS 5123-55-7C17H13NO4
N-Phenethyl phthalimide chemical structure, C16H13NO2, CAS 7501-05-5
N-Phenethyl phthalimide
CAS 7501-05-5C16H13NO2
2-[2-(4-Hydroxyphenyl)ethyl]-1H-isoindole-1,3(2H)-dione chemical structure, C16H13NO3, CAS 64985-42-8
2-[2-(4-Hydroxyphenyl)ethyl]-1H-isoindole-1,3(2H)-dione
CAS 64985-42-8C16H13NO3
(R)-2-(1,3-Dioxoisoindolin-2-yl)-3-phenylpropanoic acid chemical structure, C17H13NO4, CAS 32150-90-6
(R)-2-(1,3-Dioxoisoindolin-2-yl)-3-phenylpropanoic acid
CAS 32150-90-6C17H13NO4
1,3-Dioxo-2-(2-phenylethyl)-2,3-dihydro-1H-isoindole-5-carboxylic acid chemical structure, C17H13NO4, CAS 166096-57-7
1,3-Dioxo-2-(2-phenylethyl)-2,3-dihydro-1H-isoindole-5-carboxylic acid
CAS 166096-57-7C17H13NO4
Ethyl (alphaS)-alpha-((4-aminophenyl)methyl)-1,3-dihydro-1,3-dioxo-2H-isoindole-2-acetate chemical structure, C19H18N2O4, CAS 74743-23-0
Ethyl (alphaS)-alpha-((4-aminophenyl)methyl)-1,3-dihydro-1,3-dioxo-2H-isoindole-2-acetate
CAS 74743-23-0C19H18N2O4
2-[2-(3,4-Diethoxyphenyl)ethyl]-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxylic acid chemical structure, C21H21NO6, CAS 669704-43-2
2-[2-(3,4-Diethoxyphenyl)ethyl]-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxylic acid
CAS 669704-43-2C21H21NO6
4-(2-(1,3-Dioxoisoindolin-2-yl)ethyl)phenyl pivalate chemical structure, C21H21NO4, CAS 785849-99-2
4-(2-(1,3-Dioxoisoindolin-2-yl)ethyl)phenyl pivalate
CAS 785849-99-2C21H21NO4