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Murcko scaffold

Ring system with 3 rings and 20 atoms

9 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
9
With full pages
6
Scaffold SMILES

O=c1c(NCc2ccccc2)c[nH]n1-c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1c(NCc2ccccc2)c[nH]n1-c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

4-(Benzylamino)-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one chemical structure, C18H19N3O, CAS 23934-85-2
4-(Benzylamino)-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one
CAS 23934-85-2C18H19N3O
4-[(2-Hydroxy-3-prop-2-enylphenyl)methylamino]-1,5-dimethyl-2-phenylpyrazol-3-one chemical structure, C21H23N3O2, CAS 663217-38-7
4-[(2-Hydroxy-3-prop-2-enylphenyl)methylamino]-1,5-dimethyl-2-phenylpyrazol-3-one
CAS 663217-38-7C21H23N3O2
4-[(3,5-Dichloro-2-hydroxyphenyl)methylamino]-1,5-dimethyl-2-phenyl-3-pyrazolone chemical structure, C18H17Cl2N3O2, CAS 385421-64-7
4-[(3,5-Dichloro-2-hydroxyphenyl)methylamino]-1,5-dimethyl-2-phenyl-3-pyrazolone
CAS 385421-64-7C18H17Cl2N3O2
4-Bromo-2-[[(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)azaniumyl]methyl]phenolate chemical structure, C18H18BrN3O2, CAS 385418-41-7
4-Bromo-2-[[(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)azaniumyl]methyl]phenolate
CAS 385418-41-7C18H18BrN3O2
1,2-Dihydro-4-[[(2-hydroxy-3-methoxyphenyl)methyl]amino]-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one chemical structure, C19H21N3O3, CAS 385418-76-8
1,2-Dihydro-4-[[(2-hydroxy-3-methoxyphenyl)methyl]amino]-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one
CAS 385418-76-8C19H21N3O3
4-[1-(2-Hydroxyphenyl)ethylamino]-1,5-dimethyl-2-phenylpyrazol-3-one chemical structure, C19H21N3O2, CAS 385391-90-2
4-[1-(2-Hydroxyphenyl)ethylamino]-1,5-dimethyl-2-phenylpyrazol-3-one
CAS 385391-90-2C19H21N3O2
4-{[1-(5-Chloro-2-hydroxyphenyl)ethyl]amino}-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one chemical structure, C19H20ClN3O2, CAS 364623-87-0
4-{[1-(5-Chloro-2-hydroxyphenyl)ethyl]amino}-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one
CAS 364623-87-0C19H20ClN3O2
4-[(2-Hydroxybenzyl)amino]-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one chemical structure, C18H19N3O2, CAS 385387-37-1
4-[(2-Hydroxybenzyl)amino]-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one
CAS 385387-37-1C18H19N3O2
N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-N-(3-methylbenzyl)methanesulfonamide chemical structure, C20H23N3O3S, CAS 905800-41-1
N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-N-(3-methylbenzyl)methanesulfonamide
CAS 905800-41-1C20H23N3O3S