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Murcko scaffold

2-(Phenoxymethyl)-5-phenyl-1,3,4-oxadiazole scaffold

32 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
32
With full pages
9
Scaffold SMILES

c1ccc(OCc2nnc(-c3ccccc3)o2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(Phenoxymethyl)-5-phenyl-1,3,4-oxadiazole page
Murcko scaffold c1ccc(OCc2nnc(-c3ccccc3)o2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 32 of 32 chemicals

2-(4-Chlorophenyl)-5-[(2,4-dichlorophenoxy)methyl]-1,3,4-oxadiazole chemical structure, C15H9Cl3N2O2, CAS 338395-84-9
2-(4-Chlorophenyl)-5-[(2,4-dichlorophenoxy)methyl]-1,3,4-oxadiazole
CAS 338395-84-9C15H9Cl3N2O2
2-[(2-Chlorophenoxy)methyl]-5-(2-chlorophenyl)-1,3,4-oxadiazole chemical structure, C15H10Cl2N2O2, CAS 261962-56-5
2-[(2-Chlorophenoxy)methyl]-5-(2-chlorophenyl)-1,3,4-oxadiazole
CAS 261962-56-5C15H10Cl2N2O2
2-[(4-Chloro-2-methylphenoxy)methyl]-5-(3,4,5-trimethoxyphenyl)-1,3,4-oxadiazole chemical structure, C19H19ClN2O5, CAS 433975-41-8
2-[(4-Chloro-2-methylphenoxy)methyl]-5-(3,4,5-trimethoxyphenyl)-1,3,4-oxadiazole
CAS 433975-41-8C19H19ClN2O5
2-(4-Bromophenyl)-5-[(4-chloro-2-methylphenoxy)methyl]-1,3,4-oxadiazole chemical structure, C16H12BrClN2O2, CAS 565166-79-2
2-(4-Bromophenyl)-5-[(4-chloro-2-methylphenoxy)methyl]-1,3,4-oxadiazole
CAS 565166-79-2C16H12BrClN2O2
2-((2,4-Dichlorophenoxy)methyl)-5-(3,4,5-trimethoxyphenyl)-1,3,4-oxadiazole chemical structure, C18H16Cl2N2O5, CAS 433705-59-0
2-((2,4-Dichlorophenoxy)methyl)-5-(3,4,5-trimethoxyphenyl)-1,3,4-oxadiazole
CAS 433705-59-0C18H16Cl2N2O5
N-{2-[(5-Phenyl-1,3,4-oxadiazol-2-yl)methoxy]phenyl}acetamide chemical structure, C17H15N3O3, CAS 831244-59-8
N-{2-[(5-Phenyl-1,3,4-oxadiazol-2-yl)methoxy]phenyl}acetamide
CAS 831244-59-8C17H15N3O3
4-[[5-(2-Bromophenyl)-1,3,4-oxadiazol-2-yl]methoxy]benzaldehyde chemical structure, C16H11BrN2O3, CAS 735306-27-1
4-[[5-(2-Bromophenyl)-1,3,4-oxadiazol-2-yl]methoxy]benzaldehyde
CAS 735306-27-1C16H11BrN2O3
N-(4-((5-(4-Chlorophenyl)-1,3,4-oxadiazol-2-yl)methoxy)phenyl)acetamide chemical structure, C17H14ClN3O3, CAS 204651-69-4
N-(4-((5-(4-Chlorophenyl)-1,3,4-oxadiazol-2-yl)methoxy)phenyl)acetamide
CAS 204651-69-4C17H14ClN3O3
N-[2-[[5-(4-Chlorophenyl)-1,3,4-oxadiazol-2-yl]methoxy]phenyl]acetamide chemical structure, C17H14ClN3O3, CAS 850018-53-0
N-[2-[[5-(4-Chlorophenyl)-1,3,4-oxadiazol-2-yl]methoxy]phenyl]acetamide
CAS 850018-53-0C17H14ClN3O3
2-[(4-tert-Butylphenoxy)methyl]-5-(2-chlorophenyl)-1,3,4-oxadiazole chemical structure, C19H19ClN2O2, CAS 831239-62-4
2-[(4-tert-Butylphenoxy)methyl]-5-(2-chlorophenyl)-1,3,4-oxadiazole
CAS 831239-62-4C19H19ClN2O2
1-[3-[(5-Phenyl-1,3,4-oxadiazol-2-yl)methoxy]phenyl]ethanone chemical structure, C17H14N2O3, CAS 847240-28-2
1-[3-[(5-Phenyl-1,3,4-oxadiazol-2-yl)methoxy]phenyl]ethanone
CAS 847240-28-2C17H14N2O3
2-(2-Chlorophenyl)-5-[(2-methoxyphenoxy)methyl]-1,3,4-oxadiazole chemical structure, C16H13ClN2O3, CAS 853752-00-8
2-(2-Chlorophenyl)-5-[(2-methoxyphenoxy)methyl]-1,3,4-oxadiazole
CAS 853752-00-8C16H13ClN2O3
N-(2-{[5-(2-Chlorophenyl)-1,3,4-oxadiazol-2-yl]methoxy}phenyl)acetamide chemical structure, C17H14ClN3O3, CAS 853752-01-9
N-(2-{[5-(2-Chlorophenyl)-1,3,4-oxadiazol-2-yl]methoxy}phenyl)acetamide
CAS 853752-01-9C17H14ClN3O3
2-(Phenoxymethyl)-5-phenyl-1,3,4-oxadiazole chemical structure, C15H12N2O2, CAS 325804-03-3
2-(Phenoxymethyl)-5-phenyl-1,3,4-oxadiazole
CAS 325804-03-3C15H12N2O2
2-[(4-Methylphenoxy)methyl]-5-phenyl-1,3,4-oxadiazole chemical structure, C16H14N2O2, CAS 723325-25-5
2-[(4-Methylphenoxy)methyl]-5-phenyl-1,3,4-oxadiazole
CAS 723325-25-5C16H14N2O2
2-[(4-Chlorophenoxy)methyl]-5-phenyl-1,3,4-oxadiazole chemical structure, C15H11ClN2O2, CAS 325804-04-4
2-[(4-Chlorophenoxy)methyl]-5-phenyl-1,3,4-oxadiazole
CAS 325804-04-4C15H11ClN2O2
2-[(3-Methylphenoxy)methyl]-5-phenyl-1,3,4-oxadiazole chemical structure, C16H14N2O2, CAS 853752-02-0
2-[(3-Methylphenoxy)methyl]-5-phenyl-1,3,4-oxadiazole
CAS 853752-02-0C16H14N2O2
2-[(2,4-Dichlorophenoxy)methyl]-5-phenyl-1,3,4-oxadiazole chemical structure, C15H10Cl2N2O2, CAS 325804-05-5
2-[(2,4-Dichlorophenoxy)methyl]-5-phenyl-1,3,4-oxadiazole
CAS 325804-05-5C15H10Cl2N2O2
2-Phenyl-5-[(2,4,6-trichlorophenoxy)methyl]-1,3,4-oxadiazole chemical structure, C15H9Cl3N2O2, CAS 402939-29-1
2-Phenyl-5-[(2,4,6-trichlorophenoxy)methyl]-1,3,4-oxadiazole
CAS 402939-29-1C15H9Cl3N2O2
2-[1-(2-Bromo-4-chlorophenoxy)ethyl]-5-phenyl-1,3,4-oxadiazole chemical structure, C16H12BrClN2O2, CAS 924382-25-2
2-[1-(2-Bromo-4-chlorophenoxy)ethyl]-5-phenyl-1,3,4-oxadiazole
CAS 924382-25-2C16H12BrClN2O2
2-[1-(3,5-Dimethylphenoxy)propyl]-5-(4-methylphenyl)-1,3,4-oxadiazole chemical structure, C20H22N2O2, CAS 955288-41-2
2-[1-(3,5-Dimethylphenoxy)propyl]-5-(4-methylphenyl)-1,3,4-oxadiazole
CAS 955288-41-2C20H22N2O2
2-(2-Chlorophenyl)-5-[1-(3,5-dimethylphenoxy)propyl]-1,3,4-oxadiazole chemical structure, C19H19ClN2O2, CAS 955288-47-8
2-(2-Chlorophenyl)-5-[1-(3,5-dimethylphenoxy)propyl]-1,3,4-oxadiazole
CAS 955288-47-8C19H19ClN2O2
N-{3-Acetyl-4-[(5-phenyl-1,3,4-oxadiazol-2-yl)methoxy]phenyl}butanamide chemical structure, C21H21N3O4, CAS 924385-94-4
N-{3-Acetyl-4-[(5-phenyl-1,3,4-oxadiazol-2-yl)methoxy]phenyl}butanamide
CAS 924385-94-4C21H21N3O4
2-(2-Chlorophenyl)-5-((m-tolyloxy)methyl)-1,3,4-oxadiazole chemical structure, C16H13ClN2O2, CAS 761408-16-6
2-(2-Chlorophenyl)-5-((m-tolyloxy)methyl)-1,3,4-oxadiazole
CAS 761408-16-6C16H13ClN2O2