Murcko scaffold
2-Azetidinone scaffold
485 chemicals on CompoundList share this ring system.
- Rings
- 1
- Scaffold atoms
- 5
- Chemicals
- 485
- With full pages
- 48
Scaffold SMILES
O=C1CCN1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 97 to 144 of 485 chemicals
4-Methyl-4-carboxymethylazetidin-2-one
CAS 70997-75-0C6H9NO3
4-(Hydroxymethyl)azetidin-2-one
CAS 74694-48-7C4H7NO2
4-(Iodomethyl)azetidin-2-one
CAS 74694-50-1C4H6INO
(4S)-4-(Iodomethyl)azetidin-2-one
CAS 72776-09-1C4H6INO
4-Butylazetidin-2-one
CAS 30217-27-7C7H13NO
4-Ethylazetidin-2-one
CAS 5303-67-3C5H9NO
2-Azetidinone, 4-(ethoxyethynyl)-
CAS 74614-69-0C7H9NO2
tert-Butyl (1-hydroxy-2-oxoazetidin-3-yl)carbamate
CAS 146275-25-4C8H14N2O4
(S)-3-(N-Boc-amino)-1-hydroxy-2-azetidinone
CAS 71405-01-1C8H14N2O4
tert-Butyl (2-oxoazetidin-3-yl)carbamate
CAS 1779427-28-9C8H14N2O3
tert-Butyl N-(1-methoxy-2-oxoazetidin-3-yl)carbamate
CAS 1822344-58-0C9H16N2O4
(2S,3S)-3-Ethyl-4-oxoazetidin-2-yl acetate
CAS 73660-86-3C7H11NO3
(3R)-3-Ethyl-4-oxoazetidin-2-yl acetate
CAS 301154-81-4C7H11NO3
4-(Methylsulfanyl)azetidin-2-one
CAS 68290-18-6C4H7NOS
Ethyl (2-oxoazetidin-1-yl)acetate
CAS 54643-14-0C7H11NO3
Methyl 3-(2-oxoazetidin-1-yl)propanoate
CAS 79353-58-5C7H11NO3
4-Oxo-1-(trimethylsilyl)azetidin-2-yl acetate
CAS 80675-59-8C8H15NO3Si
Ethyl 2-(4-oxo-2-azetidinyl)propanoate
CAS 79261-32-8C8H13NO3
2-(4-Oxoazetidin-2-yl)ethyl acetate
CAS 64066-60-0C7H11NO3
4-(2-Hydroxyethyl)-2-azetidinone
CAS 64066-62-2C5H9NO2
(4R)-4-(2-Hydroxyethyl)azetidin-2-one
CAS 80559-22-4C5H9NO2
(4S)-4-(2-Hydroxyethyl)azetidin-2-one
CAS 88669-15-2C5H9NO2
Methyl 2-methyl-2-(4-oxoazetidin-2-yl)propanoate
CAS 127054-77-7C8H13NO3
2-(4-Oxoazetidin-2-yl)acetic acid
CAS 77960-43-1C5H7NO3
- 4-(2-Acetoxyethyl)-4-methyl-2-azetidinone78327-50-1C8H13NO3
- 4-(2-Hydroxyethyl)-4-methylazetidin-2-one78327-51-2C6H11NO2
- 1-[tert-Butyl(dimethyl)silyl]-4-(prop-2-en-1-yl)azetidin-2-one74819-64-0C12H23NOSi
- (4-Oxoazetidin-2-yl)methyl methanesulfonate103883-23-4C5H9NO4S
- [(2S)-4-Oxoazetidin-2-yl]methyl methanesulfonate72776-08-0C5H9NO4S
- 1-[tert-Butyl(dimethyl)silyl]-4-(iodomethyl)azetidin-2-one85390-50-7C10H20INOSi
- (4S)-1-(t-Butyldimethylsilyl)-4-iodomethyl-azetidin-2-one74288-30-5C10H20INOSi
- tert-Butyl N-[(2S,3S)-1-hydroxy-2-methyl-4-oxoazetidin-3-yl]carbamate80542-48-9C9H16N2O4
- Tts3VJ5ulf745074-59-3C4H8N2O
- tert-Butyl ((2R,3R)-2-methyl-4-oxoazetidin-3-yl)carbamate745074-60-6C9H16N2O3
- (3R)-3-Amino-3-methoxyazetidin-2-one78115-09-0C4H8N2O2
- 3-Aminoazetidin-2-one62634-84-8C3H6N2O
- (3S)-3-Aminoazetidin-2-one80582-10-1C3H6N2O
- (3S)-3-Aminoazetidin-2-one, acetic acid113791-14-3C5H10N2O3
- 3-Amino-2-oxoazetidine-1-sulfonic acid78611-11-7C3H6N2O4S
- (3S)-3-Amino-2-oxoazetidine-1-sulfonic acid79720-18-6C3H6N2O4S
- (4S)-4-({[tert-Butyl(dimethyl)silyl]oxy}methyl)azetidin-2-one87633-95-2C10H21NO2Si
- 4-Pentylazetidin-2-one109742-00-9C8H15NO
- Faropenem impurity 48104527-11-9C13H25NO4Si
- (3R,4R)-4-Acetoxy-3-((R)-(tert-butyldimethylsilyloxy)ethyl)-2-azetidinone85954-95-6C13H25NO4Si
- (3R,4R)-4-Acetoxy-3-[(R)-1-(tert-butyldimethylsilyloxy) ethyl]azetidin-2-one78963-60-7C13H25NO4Si
- Tebipenem pivoxil impurity 18C13H25NO4Si
- 4-(Chloromethyl)-4-methylazetidin-2-one53598-88-2C5H8ClNO
- 4-[(2-Hydroxyethyl)sulfanyl]azetidin-2-one73845-13-3C5H9NO2S
Related scaffolds
Same ring framework with different atoms or bond orders
